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[Clinical course of premature and newborn infants of mothers with HELLP syndrome].
Z Geburtshilfe Perinatol. 1991 Jan-Feb; 195(1):16-20.ZG

Abstract

The HELLP-syndrome is complicated by a maternal mortality of 3.5% and a perinatal mortality between 9.5 and 60%. It is a variant of severe preeclampsia which includes hemolysis, elevated liver enzymes and low platelets. It is described in the literature that neonates of mothers with HELLP-syndrome show characteristic symptoms especially thrombocytopenia, leukocytopenia and prenatal somatic dystrophy. In this retrospective investigation of 36 preterm and term infants of mothers with HELLP-syndrome we found the following results: 1. Thrombocytopenia was seen in 11% and leucocytopenia in 12% of the analysed cases. Anemia was seen in 10% of the analysed neonates. They needed transfusion of blood. The rate of prenatal somatic dystrophy was increased (58%). 2. Elevated blood pressure was observed in 29% of the neonates within the analysed interval. The time of artificial ventilation of preterm infants with maternal HELLP-syndrome was in 37% extended in comparison with infants without HELLP-syndrome in pregnancy. 3. The perinatal mortality was 8%. All observed infants during delivery and of the neonatal period in our collective survived.

Authors+Show Affiliations

Abt. Allgemeine Pädiatrie, Universitäts-Kinderklinik Kiel.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

2053379

Citation

Nikischin, W, et al. "[Clinical Course of Premature and Newborn Infants of Mothers With HELLP Syndrome]." Zeitschrift Fur Geburtshilfe Und Perinatologie, vol. 195, no. 1, 1991, pp. 16-20.
Nikischin W, Conradt A, Schröder H. [Clinical course of premature and newborn infants of mothers with HELLP syndrome]. Z Geburtshilfe Perinatol. 1991;195(1):16-20.
Nikischin, W., Conradt, A., & Schröder, H. (1991). [Clinical course of premature and newborn infants of mothers with HELLP syndrome]. Zeitschrift Fur Geburtshilfe Und Perinatologie, 195(1), 16-20.
Nikischin W, Conradt A, Schröder H. [Clinical Course of Premature and Newborn Infants of Mothers With HELLP Syndrome]. Z Geburtshilfe Perinatol. 1991 Jan-Feb;195(1):16-20. PubMed PMID: 2053379.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Clinical course of premature and newborn infants of mothers with HELLP syndrome]. AU - Nikischin,W, AU - Conradt,A, AU - Schröder,H, PY - 1991/1/1/pubmed PY - 1991/1/1/medline PY - 1991/1/1/entrez SP - 16 EP - 20 JF - Zeitschrift fur Geburtshilfe und Perinatologie JO - Z Geburtshilfe Perinatol VL - 195 IS - 1 N2 - The HELLP-syndrome is complicated by a maternal mortality of 3.5% and a perinatal mortality between 9.5 and 60%. It is a variant of severe preeclampsia which includes hemolysis, elevated liver enzymes and low platelets. It is described in the literature that neonates of mothers with HELLP-syndrome show characteristic symptoms especially thrombocytopenia, leukocytopenia and prenatal somatic dystrophy. In this retrospective investigation of 36 preterm and term infants of mothers with HELLP-syndrome we found the following results: 1. Thrombocytopenia was seen in 11% and leucocytopenia in 12% of the analysed cases. Anemia was seen in 10% of the analysed neonates. They needed transfusion of blood. The rate of prenatal somatic dystrophy was increased (58%). 2. Elevated blood pressure was observed in 29% of the neonates within the analysed interval. The time of artificial ventilation of preterm infants with maternal HELLP-syndrome was in 37% extended in comparison with infants without HELLP-syndrome in pregnancy. 3. The perinatal mortality was 8%. All observed infants during delivery and of the neonatal period in our collective survived. SN - 0300-967X UR - https://www.unboundmedicine.com/medline/citation/2053379/[Clinical_course_of_premature_and_newborn_infants_of_mothers_with_HELLP_syndrome]_ DB - PRIME DP - Unbound Medicine ER -