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Validation of Addenbrooke's cognitive examination for detecting early dementia in a Japanese population.
Psychiatry Res. 2011 Jan 30; 185(1-2):211-4.PR

Abstract

There is a clear need for brief, but sensitive and specific, cognitive screening instruments for dementia. We assessed the diagnostic accuracy of the Japanese version of Addenbrooke's Cognitive Examination (ACE) in identifying early dementia in comparison with the conventional Mini-Mental State Examination (MMSE). Standard tests for evaluating dementia screening tests were applied. A total of 201 subjects (Alzheimer's disease (AD)=65, frontotemporal dementia (FTD)=24, vascular dementia=26, dementia with Lewy bodies=11, mild cognitive impairment (MCI)=13, and controls=62) participated in this study. The reliability of the ACE was very good (alpha coefficient=0.82). In our patient series, the sensitivity for diagnosing dementia with an ACE score of ≤74 was 0.889 with a specificity of 0.987, and the sensitivity of an ACE score of ≤80 was 0.984 with a specificity of 0.867. The Japanese version of the ACE is a very accurate instrument for the detection of early dementia, and should be widely used in clinical practice.

Authors+Show Affiliations

Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama 700-8558, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20537725

Citation

Yoshida, Hidenori, et al. "Validation of Addenbrooke's Cognitive Examination for Detecting Early Dementia in a Japanese Population." Psychiatry Research, vol. 185, no. 1-2, 2011, pp. 211-4.
Yoshida H, Terada S, Honda H, et al. Validation of Addenbrooke's cognitive examination for detecting early dementia in a Japanese population. Psychiatry Res. 2011;185(1-2):211-4.
Yoshida, H., Terada, S., Honda, H., Ata, T., Takeda, N., Kishimoto, Y., Oshima, E., Ishihara, T., & Kuroda, S. (2011). Validation of Addenbrooke's cognitive examination for detecting early dementia in a Japanese population. Psychiatry Research, 185(1-2), 211-4. https://doi.org/10.1016/j.psychres.2009.06.012
Yoshida H, et al. Validation of Addenbrooke's Cognitive Examination for Detecting Early Dementia in a Japanese Population. Psychiatry Res. 2011 Jan 30;185(1-2):211-4. PubMed PMID: 20537725.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Validation of Addenbrooke's cognitive examination for detecting early dementia in a Japanese population. AU - Yoshida,Hidenori, AU - Terada,Seishi, AU - Honda,Hajime, AU - Ata,Toshie, AU - Takeda,Naoya, AU - Kishimoto,Yuki, AU - Oshima,Etsuko, AU - Ishihara,Takeshi, AU - Kuroda,Shigetoshi, PY - 2008/01/15/received PY - 2009/05/16/revised PY - 2009/06/11/accepted PY - 2010/6/12/entrez PY - 2010/6/12/pubmed PY - 2011/3/4/medline SP - 211 EP - 4 JF - Psychiatry research JO - Psychiatry Res VL - 185 IS - 1-2 N2 - There is a clear need for brief, but sensitive and specific, cognitive screening instruments for dementia. We assessed the diagnostic accuracy of the Japanese version of Addenbrooke's Cognitive Examination (ACE) in identifying early dementia in comparison with the conventional Mini-Mental State Examination (MMSE). Standard tests for evaluating dementia screening tests were applied. A total of 201 subjects (Alzheimer's disease (AD)=65, frontotemporal dementia (FTD)=24, vascular dementia=26, dementia with Lewy bodies=11, mild cognitive impairment (MCI)=13, and controls=62) participated in this study. The reliability of the ACE was very good (alpha coefficient=0.82). In our patient series, the sensitivity for diagnosing dementia with an ACE score of ≤74 was 0.889 with a specificity of 0.987, and the sensitivity of an ACE score of ≤80 was 0.984 with a specificity of 0.867. The Japanese version of the ACE is a very accurate instrument for the detection of early dementia, and should be widely used in clinical practice. SN - 0165-1781 UR - https://www.unboundmedicine.com/medline/citation/20537725/Validation_of_Addenbrooke's_cognitive_examination_for_detecting_early_dementia_in_a_Japanese_population_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0165-1781(09)00221-2 DB - PRIME DP - Unbound Medicine ER -