Tags

Type your tag names separated by a space and hit enter

Cycloartane-type glycosides from the roots of Astragalus caspicus Bieb.
Nat Prod Res. 2010 Jul; 24(11):1069-78.NP

Abstract

Two new cycloartane-type glycosides, caspicuside I and caspicuside II, were isolated along with two known saponins, cycloastragenol and astragaloside IV, from the roots of Astragalus caspicus. As the aglycon group, caspicuside I possesses 3beta,6alpha,16beta,(24S),25-pentahydroxycycloartane (cyclocanthagenol), while caspicuside II owns (20R, 24S)-epoxy-3beta, 6alpha,16beta, 25-tetrahydroxycycloartane (cycloastragenol). The chemical structures of these new cycloartane-type glycosides were established as 3-O-alpha-L-rhamnopyranosyl-16-O-beta-D-xylopyranosyl-cyclocanthogenol and 3-O-[beta-D-xylopyranosyl(1 --> 3)-beta-D-glucopyranosyl]-6-O-beta-xylopyranosyl-cycloastragenol, respectively. These findings add to a growing body of literature demonstrating the high variation of cycloartane-type triterpene glycosides in different species of Astragalus.

Authors+Show Affiliations

Department of Pharmacognosy, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran. fathiazad@tbzmed.ac.irNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20552530

Citation

Fathiazad, F, et al. "Cycloartane-type Glycosides From the Roots of Astragalus Caspicus Bieb." Natural Product Research, vol. 24, no. 11, 2010, pp. 1069-78.
Fathiazad F, Khosropanah MK, Movafeghi A. Cycloartane-type glycosides from the roots of Astragalus caspicus Bieb. Nat Prod Res. 2010;24(11):1069-78.
Fathiazad, F., Khosropanah, M. K., & Movafeghi, A. (2010). Cycloartane-type glycosides from the roots of Astragalus caspicus Bieb. Natural Product Research, 24(11), 1069-78. https://doi.org/10.1080/14786410902975582
Fathiazad F, Khosropanah MK, Movafeghi A. Cycloartane-type Glycosides From the Roots of Astragalus Caspicus Bieb. Nat Prod Res. 2010;24(11):1069-78. PubMed PMID: 20552530.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cycloartane-type glycosides from the roots of Astragalus caspicus Bieb. AU - Fathiazad,F, AU - Khosropanah,M K, AU - Movafeghi,A, PY - 2010/6/17/entrez PY - 2010/6/17/pubmed PY - 2010/9/15/medline SP - 1069 EP - 78 JF - Natural product research JO - Nat Prod Res VL - 24 IS - 11 N2 - Two new cycloartane-type glycosides, caspicuside I and caspicuside II, were isolated along with two known saponins, cycloastragenol and astragaloside IV, from the roots of Astragalus caspicus. As the aglycon group, caspicuside I possesses 3beta,6alpha,16beta,(24S),25-pentahydroxycycloartane (cyclocanthagenol), while caspicuside II owns (20R, 24S)-epoxy-3beta, 6alpha,16beta, 25-tetrahydroxycycloartane (cycloastragenol). The chemical structures of these new cycloartane-type glycosides were established as 3-O-alpha-L-rhamnopyranosyl-16-O-beta-D-xylopyranosyl-cyclocanthogenol and 3-O-[beta-D-xylopyranosyl(1 --> 3)-beta-D-glucopyranosyl]-6-O-beta-xylopyranosyl-cycloastragenol, respectively. These findings add to a growing body of literature demonstrating the high variation of cycloartane-type triterpene glycosides in different species of Astragalus. SN - 1478-6427 UR - https://www.unboundmedicine.com/medline/citation/20552530/Cycloartane_type_glycosides_from_the_roots_of_Astragalus_caspicus_Bieb_ L2 - https://www.tandfonline.com/doi/full/10.1080/14786410902975582 DB - PRIME DP - Unbound Medicine ER -