Tags

Type your tag names separated by a space and hit enter

Reassortment of pandemic H1N1/2009 influenza A virus in swine.
Science 2010; 328(5985):1529Sci

Abstract

The emergence of pandemic H1N1/2009 influenza demonstrated that pandemic viruses could be generated in swine. Subsequent reintroduction of H1N1/2009 to swine has occurred in multiple countries. Through systematic surveillance of influenza viruses in swine from a Hong Kong abattoir, we characterize a reassortant progeny of H1N1/2009 with swine viruses. Swine experimentally infected with this reassortant developed mild illness and transmitted infection to contact animals. Continued reassortment of H1N1/2009 with swine influenza viruses could produce variants with transmissibility and altered virulence for humans. Global systematic surveillance of influenza viruses in swine is warranted.

Authors+Show Affiliations

State Key Laboratory of Emerging Infectious Diseases and Department of Microbiology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong Special Administrative Region, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20558710

Citation

Vijaykrishna, D, et al. "Reassortment of Pandemic H1N1/2009 Influenza a Virus in Swine." Science (New York, N.Y.), vol. 328, no. 5985, 2010, p. 1529.
Vijaykrishna D, Poon LL, Zhu HC, et al. Reassortment of pandemic H1N1/2009 influenza A virus in swine. Science. 2010;328(5985):1529.
Vijaykrishna, D., Poon, L. L., Zhu, H. C., Ma, S. K., Li, O. T., Cheung, C. L., ... Guan, Y. (2010). Reassortment of pandemic H1N1/2009 influenza A virus in swine. Science (New York, N.Y.), 328(5985), p. 1529. doi:10.1126/science.1189132.
Vijaykrishna D, et al. Reassortment of Pandemic H1N1/2009 Influenza a Virus in Swine. Science. 2010 Jun 18;328(5985):1529. PubMed PMID: 20558710.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Reassortment of pandemic H1N1/2009 influenza A virus in swine. AU - Vijaykrishna,D, AU - Poon,L L M, AU - Zhu,H C, AU - Ma,S K, AU - Li,O T W, AU - Cheung,C L, AU - Smith,G J D, AU - Peiris,J S M, AU - Guan,Y, PY - 2010/6/19/entrez PY - 2010/6/19/pubmed PY - 2010/7/2/medline SP - 1529 EP - 1529 JF - Science (New York, N.Y.) JO - Science VL - 328 IS - 5985 N2 - The emergence of pandemic H1N1/2009 influenza demonstrated that pandemic viruses could be generated in swine. Subsequent reintroduction of H1N1/2009 to swine has occurred in multiple countries. Through systematic surveillance of influenza viruses in swine from a Hong Kong abattoir, we characterize a reassortant progeny of H1N1/2009 with swine viruses. Swine experimentally infected with this reassortant developed mild illness and transmitted infection to contact animals. Continued reassortment of H1N1/2009 with swine influenza viruses could produce variants with transmissibility and altered virulence for humans. Global systematic surveillance of influenza viruses in swine is warranted. SN - 1095-9203 UR - https://www.unboundmedicine.com/medline/citation/20558710/Reassortment_of_pandemic_H1N1/2009_influenza_A_virus_in_swine_ L2 - http://www.sciencemag.org/cgi/pmidlookup?view=long&pmid=20558710 DB - PRIME DP - Unbound Medicine ER -