Citation
Litaker, R Wayne, et al. "Global Distribution of Ciguatera Causing Dinoflagellates in the Genus Gambierdiscus." Toxicon : Official Journal of the International Society On Toxinology, vol. 56, no. 5, 2010, pp. 711-30.
Litaker RW, Vandersea MW, Faust MA, et al. Global distribution of ciguatera causing dinoflagellates in the genus Gambierdiscus. Toxicon. 2010;56(5):711-30.
Litaker, R. W., Vandersea, M. W., Faust, M. A., Kibler, S. R., Nau, A. W., Holland, W. C., Chinain, M., Holmes, M. J., & Tester, P. A. (2010). Global distribution of ciguatera causing dinoflagellates in the genus Gambierdiscus. Toxicon : Official Journal of the International Society On Toxinology, 56(5), 711-30. https://doi.org/10.1016/j.toxicon.2010.05.017
Litaker RW, et al. Global Distribution of Ciguatera Causing Dinoflagellates in the Genus Gambierdiscus. Toxicon. 2010;56(5):711-30. PubMed PMID: 20561539.
TY - JOUR
T1 - Global distribution of ciguatera causing dinoflagellates in the genus Gambierdiscus.
AU - Litaker,R Wayne,
AU - Vandersea,Mark W,
AU - Faust,Maria A,
AU - Kibler,Steven R,
AU - Nau,Amy W,
AU - Holland,William C,
AU - Chinain,Mireille,
AU - Holmes,Michael J,
AU - Tester,Patricia A,
Y1 - 2010/06/16/
PY - 2009/07/14/received
PY - 2010/05/21/revised
PY - 2010/05/28/accepted
PY - 2010/6/22/entrez
PY - 2010/6/22/pubmed
PY - 2010/12/25/medline
SP - 711
EP - 30
JF - Toxicon : official journal of the International Society on Toxinology
JO - Toxicon
VL - 56
IS - 5
N2 - Dinoflagellates in the genus Gambierdiscus produce toxins that bioaccumulate in tropical and sub-tropical fishes causing ciguatera fish poisoning (CFP). Little is known about the diversity and distribution of Gambierdiscus species, the degree to which individual species vary in toxicity, and the role each plays in causing CFP. This paper presents the first global distribution of Gambierdiscus species. Phylogenetic analyses of the existing isolates indicate that five species are endemic to the Atlantic (including the Caribbean/West Indies and Gulf of Mexico), five are endemic to the tropical Pacific, and that two species, Gambierdiscus carpenteri and Gambierdiscus caribaeus are globally distributed. The differences in Gambierdiscus species composition in the Atlantic and Pacific correlated with structural differences in the ciguatoxins reported from Atlantic and Pacific fish. This correlation supports the hypothesis that Gambierdiscus species in each region produce different toxin suites. A literature survey indicated a >100-fold variation in toxicity among species compared with a 2 to 9-fold within species variation due to changing growth conditions. These observations suggest that CFP events are driven more by inherent differences in species toxicity than by environmental modulation. How variations in species toxicity may affect the development of an early warning system for CFP is discussed.
SN - 1879-3150
UR - https://www.unboundmedicine.com/medline/citation/20561539/Global_distribution_of_ciguatera_causing_dinoflagellates_in_the_genus_Gambierdiscus_
L2 - https://linkinghub.elsevier.com/retrieve/pii/S0041-0101(10)00214-X
DB - PRIME
DP - Unbound Medicine
ER -