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Tea and coffee consumption and cardiovascular morbidity and mortality.
Arterioscler Thromb Vasc Biol 2010; 30(8):1665-71AT

Abstract

OBJECTIVE

To examine the associations of coffee and tea consumption with risk of morbidity and mortality of stroke and coronary heart disease (CHD) and with all-cause mortality.

METHODS AND RESULTS

Coffee and tea consumption were assessed with a validated food-frequency questionnaire, and 37 514 participants were observed for 13 years for the occurrence of cardiovascular morbidity and mortality. A U-shaped association between coffee and CHD was found, with the lowest hazard ratio (HR [95% CI]) for 2.1 to 3.0 cups per day (0.79 [0.65 to 0.96]; P(trend)=0.01). Tea was inversely associated with CHD, with the lowest HR (95% CI) for more than 6.0 cups per day (0.64 [0.46 to 0.90]; P(trend)=0.02). No associations between tea or coffee and stroke were found (P(trend)=0.63 and P(trend)=0.32, respectively). Although not significant, coffee slightly reduced the risk for CHD mortality (HR, 0.64; 95% CI, 0.37 to 1.11; P(trend)=0.12) for 3.1 to 6.0 cups per day. A U-shaped association between tea and CHD mortality was observed, with an HR of 0.55 (95% CI, 0.31 to 0.97; P(trend)=0.03) for 3.1 to 6.0 cups per day. Neither coffee nor tea was associated with stroke (P(trend)=0.22 and P(trend)=0.74, respectively) and all-cause mortality (P(trend)=0.33 and P(trend)=0.43, respectively).

CONCLUSIONS

High tea consumption is associated with a reduced risk of CHD mortality. Our results suggest a slight risk reduction for CHD mortality with moderate coffee consumption and strengthen the evidence on the lower risk of CHD with coffee and tea consumption.

Authors+Show Affiliations

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20562351

Citation

de Koning Gans, J Margot, et al. "Tea and Coffee Consumption and Cardiovascular Morbidity and Mortality." Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 30, no. 8, 2010, pp. 1665-71.
de Koning Gans JM, Uiterwaal CS, van der Schouw YT, et al. Tea and coffee consumption and cardiovascular morbidity and mortality. Arterioscler Thromb Vasc Biol. 2010;30(8):1665-71.
de Koning Gans, J. M., Uiterwaal, C. S., van der Schouw, Y. T., Boer, J. M., Grobbee, D. E., Verschuren, W. M., & Beulens, J. W. (2010). Tea and coffee consumption and cardiovascular morbidity and mortality. Arteriosclerosis, Thrombosis, and Vascular Biology, 30(8), pp. 1665-71. doi:10.1161/ATVBAHA.109.201939.
de Koning Gans JM, et al. Tea and Coffee Consumption and Cardiovascular Morbidity and Mortality. Arterioscler Thromb Vasc Biol. 2010;30(8):1665-71. PubMed PMID: 20562351.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Tea and coffee consumption and cardiovascular morbidity and mortality. AU - de Koning Gans,J Margot, AU - Uiterwaal,Cuno S P M, AU - van der Schouw,Yvonne T, AU - Boer,Jolanda M A, AU - Grobbee,Diederick E, AU - Verschuren,W M Monique, AU - Beulens,Joline W J, Y1 - 2010/06/18/ PY - 2010/6/22/entrez PY - 2010/6/22/pubmed PY - 2010/8/11/medline SP - 1665 EP - 71 JF - Arteriosclerosis, thrombosis, and vascular biology JO - Arterioscler. Thromb. Vasc. Biol. VL - 30 IS - 8 N2 - OBJECTIVE: To examine the associations of coffee and tea consumption with risk of morbidity and mortality of stroke and coronary heart disease (CHD) and with all-cause mortality. METHODS AND RESULTS: Coffee and tea consumption were assessed with a validated food-frequency questionnaire, and 37 514 participants were observed for 13 years for the occurrence of cardiovascular morbidity and mortality. A U-shaped association between coffee and CHD was found, with the lowest hazard ratio (HR [95% CI]) for 2.1 to 3.0 cups per day (0.79 [0.65 to 0.96]; P(trend)=0.01). Tea was inversely associated with CHD, with the lowest HR (95% CI) for more than 6.0 cups per day (0.64 [0.46 to 0.90]; P(trend)=0.02). No associations between tea or coffee and stroke were found (P(trend)=0.63 and P(trend)=0.32, respectively). Although not significant, coffee slightly reduced the risk for CHD mortality (HR, 0.64; 95% CI, 0.37 to 1.11; P(trend)=0.12) for 3.1 to 6.0 cups per day. A U-shaped association between tea and CHD mortality was observed, with an HR of 0.55 (95% CI, 0.31 to 0.97; P(trend)=0.03) for 3.1 to 6.0 cups per day. Neither coffee nor tea was associated with stroke (P(trend)=0.22 and P(trend)=0.74, respectively) and all-cause mortality (P(trend)=0.33 and P(trend)=0.43, respectively). CONCLUSIONS: High tea consumption is associated with a reduced risk of CHD mortality. Our results suggest a slight risk reduction for CHD mortality with moderate coffee consumption and strengthen the evidence on the lower risk of CHD with coffee and tea consumption. SN - 1524-4636 UR - https://www.unboundmedicine.com/medline/citation/20562351/Tea_and_coffee_consumption_and_cardiovascular_morbidity_and_mortality_ L2 - http://www.ahajournals.org/doi/full/10.1161/ATVBAHA.109.201939?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -