Tags

Type your tag names separated by a space and hit enter

Bioactivity of major components from the seeds of Bunium persicum (Boiss.) Fedtch.
Pak J Pharm Sci. 2010 Jul; 23(3):300-4.PJ

Abstract

Zire Kermani (Bunium persicum) is an Iranian plant which is commonly used as antispasmodic, carminative, anti obesity and lactogage. The essential oil and different extracts of the seeds of this plant were evaluated for antioxidant activity by three complementary methods: DPPH assay, beta-carotene bleaching and ammonium thiocyanate methods. The oil and methanolic extract of B. persicum exhibited the highest antioxidant activity with IC50 = 23.4 +/- 1.6 and 45.7 +/- 3.6 microg mL(-1) in DPPH assay and the most inhibition of beta-carotene oxidation and lipid peroxidation. The GC/MS analysis of the essential oil of B. persicum indicated the gamma-Terpinene (46.1%) and cuminaldehyde (15.5%) as the major components of the oil. Furthermore the active methanol extract of the plant was fractioned by column chromatography to afford several fractions, of which in more purification, kaempferol, caffeic acid and p-coumaric acid were found to be the antioxidant components of this extract. These results confirm the in vitro antioxidant and radical scavenging activity of the essential oil and methanolic extract of B. persicum, which warranty the use of the plant in many traditional uses.

Authors+Show Affiliations

Sharififar F
Kerman University of Medical Sciences, Pharmaceutics Research Center, Department of Pharmacognosy, School of Pharmacy, Kerman, Iran. fsharififar@Kmu.ac.ir
Yassa N
No affiliation info available
Mozaffarian V
No affiliation info available

MeSH

AntioxidantsApiaceaeCyclohexane MonoterpenesMonoterpenesOils, VolatilePlant ExtractsSeeds

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20566444

Citation

Sharififar, Fariba, et al. "Bioactivity of Major Components From the Seeds of Bunium Persicum (Boiss.) Fedtch." Pakistan Journal of Pharmaceutical Sciences, vol. 23, no. 3, 2010, pp. 300-4.
Sharififar F, Yassa N, Mozaffarian V. Bioactivity of major components from the seeds of Bunium persicum (Boiss.) Fedtch. Pak J Pharm Sci. 2010;23(3):300-4.
Sharififar, F., Yassa, N., & Mozaffarian, V. (2010). Bioactivity of major components from the seeds of Bunium persicum (Boiss.) Fedtch. Pakistan Journal of Pharmaceutical Sciences, 23(3), 300-4.
Sharififar F, Yassa N, Mozaffarian V. Bioactivity of Major Components From the Seeds of Bunium Persicum (Boiss.) Fedtch. Pak J Pharm Sci. 2010;23(3):300-4. PubMed PMID: 20566444.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Bioactivity of major components from the seeds of Bunium persicum (Boiss.) Fedtch. AU - Sharififar,Fariba, AU - Yassa,Narguess, AU - Mozaffarian,Valiolah, PY - 2010/6/23/entrez PY - 2010/6/23/pubmed PY - 2010/8/6/medline SP - 300 EP - 4 JF - Pakistan journal of pharmaceutical sciences JO - Pak J Pharm Sci VL - 23 IS - 3 N2 - Zire Kermani (Bunium persicum) is an Iranian plant which is commonly used as antispasmodic, carminative, anti obesity and lactogage. The essential oil and different extracts of the seeds of this plant were evaluated for antioxidant activity by three complementary methods: DPPH assay, beta-carotene bleaching and ammonium thiocyanate methods. The oil and methanolic extract of B. persicum exhibited the highest antioxidant activity with IC50 = 23.4 +/- 1.6 and 45.7 +/- 3.6 microg mL(-1) in DPPH assay and the most inhibition of beta-carotene oxidation and lipid peroxidation. The GC/MS analysis of the essential oil of B. persicum indicated the gamma-Terpinene (46.1%) and cuminaldehyde (15.5%) as the major components of the oil. Furthermore the active methanol extract of the plant was fractioned by column chromatography to afford several fractions, of which in more purification, kaempferol, caffeic acid and p-coumaric acid were found to be the antioxidant components of this extract. These results confirm the in vitro antioxidant and radical scavenging activity of the essential oil and methanolic extract of B. persicum, which warranty the use of the plant in many traditional uses. SN - 1011-601X UR - https://www.unboundmedicine.com/medline/citation/20566444/Bioactivity_of_major_components_from_the_seeds_of_Bunium_persicum__Boiss___Fedtch_ L2 - https://medlineplus.gov/antioxidants.html DB - PRIME DP - Unbound Medicine ER -