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[CD80 and CD86 coreceptors expression on lymphocytes B in hypertrophied adenoids in children with otitis media with effusion].
Otolaryngol Pol. 2010 Mar-Apr; 64(2):93-7.OP

Abstract

AIM

The aim of this study was evaluation of the percentage and mean fluorescence intensity of lymphocytes B with expression CD80 and CD86 in hypertrophied adenoids in children with otitis media with effusion.

MATERIAL AND METHODS

Expression coreceptors CD80 and CD86 on lymphocytes B in adenoid tissue were estimated by flow cytometry method. 15 children with otitis media with effusion and 15 children with hypertrophied adenoid were tested.

RESULTS

This study showed significantly higher percentage of lymphocytes CD19+ CD80+ in children with otitis media with effusion (OME 1.42% +/- 0.91) than in comparative group with hypertrophied adenoids (AH 0.63% +/- 0.21). The receptor CD86 didn't show differences in expression on lymphocytes B between both examinated groups.

CONCLUSION

Low expression of CD80 and CD86 indicates that local immunity response in hypertrophied adenoids in children with otitis media with effusion is weakened. It can contribute to the otitis media with effusion.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Ratomski K
Zaklad Laboratoryjnej Diagnostyki, Pediatrycznej Uniwersytetu Medycznego w Białymstoku. karol.cam@interia.pl
Zelazowska-Rutkowska B
No affiliation info available
Wysocka J
No affiliation info available
Skotnicka B
No affiliation info available
Kasprzycka E
No affiliation info available
Ilona B
No affiliation info available

MeSH

AdenoidsAdolescentB-LymphocytesB7-1 AntigenB7-2 AntigenChildChild, PreschoolFemaleHumansHypertrophyMaleOtitis Media with EffusionPolandSeverity of Illness IndexStatistics, Nonparametric

Pub Type(s)

Journal Article

Language

pol

PubMed ID

20568537

Citation

Ratomski, Karol, et al. "[CD80 and CD86 Coreceptors Expression On Lymphocytes B in Hypertrophied Adenoids in Children With Otitis Media With Effusion]." Otolaryngologia Polska = the Polish Otolaryngology, vol. 64, no. 2, 2010, pp. 93-7.
Ratomski K, Zelazowska-Rutkowska B, Wysocka J, et al. [CD80 and CD86 coreceptors expression on lymphocytes B in hypertrophied adenoids in children with otitis media with effusion]. Otolaryngol Pol. 2010;64(2):93-7.
Ratomski, K., Zelazowska-Rutkowska, B., Wysocka, J., Skotnicka, B., Kasprzycka, E., & Ilona, B. (2010). [CD80 and CD86 coreceptors expression on lymphocytes B in hypertrophied adenoids in children with otitis media with effusion]. Otolaryngologia Polska = the Polish Otolaryngology, 64(2), 93-7. https://doi.org/10.1016/S0030-6657(10)70042-1
Ratomski K, et al. [CD80 and CD86 Coreceptors Expression On Lymphocytes B in Hypertrophied Adenoids in Children With Otitis Media With Effusion]. Otolaryngol Pol. 2010 Mar-Apr;64(2):93-7. PubMed PMID: 20568537.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [CD80 and CD86 coreceptors expression on lymphocytes B in hypertrophied adenoids in children with otitis media with effusion]. AU - Ratomski,Karol, AU - Zelazowska-Rutkowska,Beata, AU - Wysocka,Jolanta, AU - Skotnicka,Bozena, AU - Kasprzycka,Edwina, AU - Ilona,Bauer, PY - 2010/6/24/entrez PY - 2010/6/24/pubmed PY - 2010/8/21/medline SP - 93 EP - 7 JF - Otolaryngologia polska = The Polish otolaryngology JO - Otolaryngol Pol VL - 64 IS - 2 N2 - AIM: The aim of this study was evaluation of the percentage and mean fluorescence intensity of lymphocytes B with expression CD80 and CD86 in hypertrophied adenoids in children with otitis media with effusion. MATERIAL AND METHODS: Expression coreceptors CD80 and CD86 on lymphocytes B in adenoid tissue were estimated by flow cytometry method. 15 children with otitis media with effusion and 15 children with hypertrophied adenoid were tested. RESULTS: This study showed significantly higher percentage of lymphocytes CD19+ CD80+ in children with otitis media with effusion (OME 1.42% +/- 0.91) than in comparative group with hypertrophied adenoids (AH 0.63% +/- 0.21). The receptor CD86 didn't show differences in expression on lymphocytes B between both examinated groups. CONCLUSION: Low expression of CD80 and CD86 indicates that local immunity response in hypertrophied adenoids in children with otitis media with effusion is weakened. It can contribute to the otitis media with effusion. SN - 0030-6657 UR - https://www.unboundmedicine.com/medline/citation/20568537/[CD80_and_CD86_coreceptors_expression_on_lymphocytes_B_in_hypertrophied_adenoids_in_children_with_otitis_media_with_effusion]_ DB - PRIME DP - Unbound Medicine ER -