Tags

Type your tag names separated by a space and hit enter

[Hypertriglyceridemia-induced pancreatitis treated with insulin in a nondiabetic patient].
Korean J Gastroenterol. 2010 Jun; 55(6):399-403.KJ

Abstract

Heparin and/or insulin stimulate lipoprotein lipase and are known to decrease serum triglyceride level. However, their efficacy in hypertriglyceridemia-induced acute pancreatitis in nondiabetic patients is not well documented. We report a case of hypertriglyceridemia-induced pancreatitis in 43-year-old nondiabetic woman in whom treatment with insulin was accompanied by reduction in serum triglyceride level and the resolution of pancreatitis. She presented to the emergency department with abdominal pain and biochemical evidence of acute pancreatitis. Her medical history was unremarkable. There was no history of alcohol consumption, and biliary imaging was not remarkable. Subsequent laboratory investigation revealed marked hypertriglyceridemia (1,951 mg/dL), impaired fasting glucose, and normal HbAlc level. The Ransons score and APATCH II score were 1 and 4. Abdominal CT showed diffuse enlargement of pancreas, peripancreatic fat infiltration, and multiple fluid collections around the pancreas. We treated the patient with the infusion of 5% dextrose and 1.5 unit/hr regular insulin to reduce serum triglyceride level. The level of serum triglyceride was decreased to 305 mg/dL on day 5. During the remainder of hospitalization, her clinical symptoms and laboratory values gradually improved.

Authors+Show Affiliations

Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

kor

PubMed ID

20571309

Citation

Park, Seon Young, et al. "[Hypertriglyceridemia-induced Pancreatitis Treated With Insulin in a Nondiabetic Patient]." The Korean Journal of Gastroenterology = Taehan Sohwagi Hakhoe Chi, vol. 55, no. 6, 2010, pp. 399-403.
Park SY, Chung JO, Cho DK, et al. [Hypertriglyceridemia-induced pancreatitis treated with insulin in a nondiabetic patient]. Korean J Gastroenterol. 2010;55(6):399-403.
Park, S. Y., Chung, J. O., Cho, D. K., Lee, W. S., Kim, H. S., Choi, S. K., Rew, J. S., & Chung, M. Y. (2010). [Hypertriglyceridemia-induced pancreatitis treated with insulin in a nondiabetic patient]. The Korean Journal of Gastroenterology = Taehan Sohwagi Hakhoe Chi, 55(6), 399-403. https://doi.org/2010062509
Park SY, et al. [Hypertriglyceridemia-induced Pancreatitis Treated With Insulin in a Nondiabetic Patient]. Korean J Gastroenterol. 2010;55(6):399-403. PubMed PMID: 20571309.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Hypertriglyceridemia-induced pancreatitis treated with insulin in a nondiabetic patient]. AU - Park,Seon Young, AU - Chung,Jin Ook, AU - Cho,Dong Keun, AU - Lee,Wan Sik, AU - Kim,Hyun Soo, AU - Choi,Sung-Kyu, AU - Rew,Jong-Sun, AU - Chung,Min Young, PY - 2010/6/24/entrez PY - 2010/6/24/pubmed PY - 2010/8/13/medline SP - 399 EP - 403 JF - The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi JO - Korean J Gastroenterol VL - 55 IS - 6 N2 - Heparin and/or insulin stimulate lipoprotein lipase and are known to decrease serum triglyceride level. However, their efficacy in hypertriglyceridemia-induced acute pancreatitis in nondiabetic patients is not well documented. We report a case of hypertriglyceridemia-induced pancreatitis in 43-year-old nondiabetic woman in whom treatment with insulin was accompanied by reduction in serum triglyceride level and the resolution of pancreatitis. She presented to the emergency department with abdominal pain and biochemical evidence of acute pancreatitis. Her medical history was unremarkable. There was no history of alcohol consumption, and biliary imaging was not remarkable. Subsequent laboratory investigation revealed marked hypertriglyceridemia (1,951 mg/dL), impaired fasting glucose, and normal HbAlc level. The Ransons score and APATCH II score were 1 and 4. Abdominal CT showed diffuse enlargement of pancreas, peripancreatic fat infiltration, and multiple fluid collections around the pancreas. We treated the patient with the infusion of 5% dextrose and 1.5 unit/hr regular insulin to reduce serum triglyceride level. The level of serum triglyceride was decreased to 305 mg/dL on day 5. During the remainder of hospitalization, her clinical symptoms and laboratory values gradually improved. SN - 1598-9992 UR - https://www.unboundmedicine.com/medline/citation/20571309/[Hypertriglyceridemia_induced_pancreatitis_treated_with_insulin_in_a_nondiabetic_patient]_ L2 - http://old.gastrokorea.org/journal/viewJournal.html?year=2010&vol=55&iss=6&page=399 DB - PRIME DP - Unbound Medicine ER -