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Renal artery stenting in patients with chronic ischemic heart disease.
Catheter Cardiovasc Interv. 2010 Jul 01; 76(1):26-34.CC

Abstract

OBJECTIVES

To investigate the role of renal stenting in selected patients with chronic ischemic heart disease and renal artery stenosis.

METHODS

Consecutive patients, with chronic ischemic heart disease and severe hypertension and/or impaired renal function undergoing renal stenting, were prospectively enrolled. Mid-term (at least 2 years) follow-up was performed to assess both changes in renal function [serum creatinine and estimated glomerular filtrate rate (eGFR)] and blood pressure (BP) control (number of required drugs) and to record the incidence of clinical major adverse events. Moreover, in the first consecutive 24 patients, out-of-range pressure values at 24-hr BP monitoring and GFR at renal scintigraphy were measured at baseline and 1 month after stenting.

RESULTS

Seventy patients treated by stenting on 86 renal arteries entered the study. Procedural success rate was 99% and no major complication occurred. At 2-year follow-up, both mean serum creatinine (-0.1 +/- 0.7 mg/dl at follow-up compared to baseline, P = 0.6) and eGFR (+3.7 +/- 23.5 ml/min/1.73m(2) at follow-up compared to baseline, P = 0.2) did not significantly change while the number of drugs required to control BP significantly decreased (2.7 +/- 0.8 to 2.2 +/- 0.7, P < 0.0001). In the subset of 24 patients evaluated at 1 month, GFR significantly increased (62 +/- 20 ml/min to 67 +/- 21 ml/min; P = 0.008) and the rate of the out-of-range systolic pressure values at 24-hr monitoring significantly decreased (51-33%, P = 0.005). Elevated baseline creatinine values and the presence of global renal ischemia were identified as predictors of poor outcome at the multivariate analysis.

CONCLUSIONS

In selected patients with chronic ischemic heart disease and hypertension and/or renal insufficiency, renal stenting may be performed with very low periprocedural complications and results in unchanged renal function and improved BP control.

Authors+Show Affiliations

Department of Cardiology, Catholic University of the Sacred Heart, Viale G. Rossini 74, Rome, Italy. carlotrani@rm.unicatt.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20578190

Citation

Trani, Carlo, et al. "Renal Artery Stenting in Patients With Chronic Ischemic Heart Disease." Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions, vol. 76, no. 1, 2010, pp. 26-34.
Trani C, Tommasino A, Giammarinaro M, et al. Renal artery stenting in patients with chronic ischemic heart disease. Catheter Cardiovasc Interv. 2010;76(1):26-34.
Trani, C., Tommasino, A., Giammarinaro, M., Burzotta, F., Coroleu, S. F., Rufini, V., Mazzari, M. A., Porto, I., Niccoli, G., Leone, A. M., Mongiardo, R., Gabrielli, F. A., Schiavoni, G., Biamino, G., & Crea, F. (2010). Renal artery stenting in patients with chronic ischemic heart disease. Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions, 76(1), 26-34. https://doi.org/10.1002/ccd.22525
Trani C, et al. Renal Artery Stenting in Patients With Chronic Ischemic Heart Disease. Catheter Cardiovasc Interv. 2010 Jul 1;76(1):26-34. PubMed PMID: 20578190.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Renal artery stenting in patients with chronic ischemic heart disease. AU - Trani,Carlo, AU - Tommasino,Antonella, AU - Giammarinaro,Maura, AU - Burzotta,Francesco, AU - Coroleu,Santiago Federico, AU - Rufini,Vittoria, AU - Mazzari,Mario Attilio, AU - Porto,Italo, AU - Niccoli,Giampaolo, AU - Leone,Antonio Maria, AU - Mongiardo,Rocco, AU - Gabrielli,Francesca Augusta, AU - Schiavoni,Giovanni, AU - Biamino,Giancarlo, AU - Crea,Filippo, PY - 2010/6/26/entrez PY - 2010/6/26/pubmed PY - 2010/10/16/medline SP - 26 EP - 34 JF - Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions JO - Catheter Cardiovasc Interv VL - 76 IS - 1 N2 - OBJECTIVES: To investigate the role of renal stenting in selected patients with chronic ischemic heart disease and renal artery stenosis. METHODS: Consecutive patients, with chronic ischemic heart disease and severe hypertension and/or impaired renal function undergoing renal stenting, were prospectively enrolled. Mid-term (at least 2 years) follow-up was performed to assess both changes in renal function [serum creatinine and estimated glomerular filtrate rate (eGFR)] and blood pressure (BP) control (number of required drugs) and to record the incidence of clinical major adverse events. Moreover, in the first consecutive 24 patients, out-of-range pressure values at 24-hr BP monitoring and GFR at renal scintigraphy were measured at baseline and 1 month after stenting. RESULTS: Seventy patients treated by stenting on 86 renal arteries entered the study. Procedural success rate was 99% and no major complication occurred. At 2-year follow-up, both mean serum creatinine (-0.1 +/- 0.7 mg/dl at follow-up compared to baseline, P = 0.6) and eGFR (+3.7 +/- 23.5 ml/min/1.73m(2) at follow-up compared to baseline, P = 0.2) did not significantly change while the number of drugs required to control BP significantly decreased (2.7 +/- 0.8 to 2.2 +/- 0.7, P < 0.0001). In the subset of 24 patients evaluated at 1 month, GFR significantly increased (62 +/- 20 ml/min to 67 +/- 21 ml/min; P = 0.008) and the rate of the out-of-range systolic pressure values at 24-hr monitoring significantly decreased (51-33%, P = 0.005). Elevated baseline creatinine values and the presence of global renal ischemia were identified as predictors of poor outcome at the multivariate analysis. CONCLUSIONS: In selected patients with chronic ischemic heart disease and hypertension and/or renal insufficiency, renal stenting may be performed with very low periprocedural complications and results in unchanged renal function and improved BP control. SN - 1522-726X UR - https://www.unboundmedicine.com/medline/citation/20578190/Renal_artery_stenting_in_patients_with_chronic_ischemic_heart_disease_ L2 - https://doi.org/10.1002/ccd.22525 DB - PRIME DP - Unbound Medicine ER -