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Xanthogranuloma of the sellar region--case report.
Neurol Med Chir (Tokyo). 2010; 50(6):488-91.NM

Abstract

A 55-year-old woman presented with a rare xanthogranuloma of the sellar region after complaining of severe headache and visual disturbance 3 months previously. Clinical examination showed she was alert with early signs of bitemporal hemianopsia. Endocrinological examination revealed hypopituitarism. Magnetic resonance imaging showed an intrasellar mass extending into the suprasellar region and compressing the optic chiasma, which appeared homogeneously hyperintense on T(1)-weighted images. Endonasal transsphenoidal resection of the tumor was performed. Histological examination disclosed granulomatous tissue with cholesterol clefts, hemosiderin deposits, fibrous tissues, and macrophages containing rich fat. The histological diagnosis was xanthogranuloma of the sellar region. Her visual symptoms recovered postoperatively although the hypopituitarism remained. Xanthogranuloma of the sellar region is rare, but must be considered in the differential diagnosis of tumors of the sellar region.

Authors+Show Affiliations

Arai A
Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan.
Nishihara M
No affiliation info available
Sasayama T
No affiliation info available
Aihara H
No affiliation info available
Hosoda K
No affiliation info available
Itoh T
No affiliation info available
Sakagami Y
No affiliation info available
Kuwamura K
No affiliation info available
Kohmura E
No affiliation info available

MeSH

FemaleHumansHypopituitarismMiddle AgedRadiographySella TurcicaSkull Base NeoplasmsTreatment OutcomeXanthogranuloma, Juvenile

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

20587976

Citation

Arai, Atsushi, et al. "Xanthogranuloma of the Sellar Region--case Report." Neurologia Medico-chirurgica, vol. 50, no. 6, 2010, pp. 488-91.
Arai A, Nishihara M, Sasayama T, et al. Xanthogranuloma of the sellar region--case report. Neurol Med Chir (Tokyo). 2010;50(6):488-91.
Arai, A., Nishihara, M., Sasayama, T., Aihara, H., Hosoda, K., Itoh, T., Sakagami, Y., Kuwamura, K., & Kohmura, E. (2010). Xanthogranuloma of the sellar region--case report. Neurologia Medico-chirurgica, 50(6), 488-91.
Arai A, et al. Xanthogranuloma of the Sellar Region--case Report. Neurol Med Chir (Tokyo). 2010;50(6):488-91. PubMed PMID: 20587976.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Xanthogranuloma of the sellar region--case report. AU - Arai,Atsushi, AU - Nishihara,Masamitsu, AU - Sasayama,Takashi, AU - Aihara,Hideo, AU - Hosoda,Kohkichi, AU - Itoh,Tomoo, AU - Sakagami,Yoshio, AU - Kuwamura,Keiichi, AU - Kohmura,Eiji, PY - 2010/7/1/entrez PY - 2010/7/1/pubmed PY - 2011/7/19/medline SP - 488 EP - 91 JF - Neurologia medico-chirurgica JO - Neurol Med Chir (Tokyo) VL - 50 IS - 6 N2 - A 55-year-old woman presented with a rare xanthogranuloma of the sellar region after complaining of severe headache and visual disturbance 3 months previously. Clinical examination showed she was alert with early signs of bitemporal hemianopsia. Endocrinological examination revealed hypopituitarism. Magnetic resonance imaging showed an intrasellar mass extending into the suprasellar region and compressing the optic chiasma, which appeared homogeneously hyperintense on T(1)-weighted images. Endonasal transsphenoidal resection of the tumor was performed. Histological examination disclosed granulomatous tissue with cholesterol clefts, hemosiderin deposits, fibrous tissues, and macrophages containing rich fat. The histological diagnosis was xanthogranuloma of the sellar region. Her visual symptoms recovered postoperatively although the hypopituitarism remained. Xanthogranuloma of the sellar region is rare, but must be considered in the differential diagnosis of tumors of the sellar region. SN - 1349-8029 UR - https://www.unboundmedicine.com/medline/citation/20587976/Xanthogranuloma_of_the_sellar_region__case_report_ DB - PRIME DP - Unbound Medicine ER -