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The effect of farmed trout on cardiovascular risk markers in healthy men.
Br J Nutr. 2010 Nov; 104(10):1528-36.BJ

Abstract

Increased intake of marine long-chain n-3 PUFA (n-3 LCPUFA) may decrease the risk of CVD and reduce mortality by lowering serum TAG and blood pressure (BP). Furthermore, n-3 LCPUFA may affect novel CVD risk markers related to inflammation and vascular function. The objective of the present study was to examine the effect of farmed trout on novel and traditional CVD risk markers in healthy men, and to evaluate whether this was affected by the aquacultural feed regime. We performed a parallel, 8-week intervention study in which sixty-eight healthy male volunteers were randomised to consume either a daily meal with 150 g farmed trout raised on either marine or vegetable-based feed, or a reference meal containing 150 g chicken. Twenty-four hour BP, pulse wave velocity, augmentation index, fatty acid composition of erythrocyte (RBC), and concentrations of TAG, HDL-cholesterol, LDL-cholesterol, glucose, insulin, C-reactive protein (CRP) and other markers of inflammation were measured at weeks 0 and 8. RBC content of total n-3 LCPUFA, both EPA and DHA, was significantly higher among men consuming trout raised on marine feed compared with men consuming the vegetable-fed trout or chicken. The three intervention groups did not differ significantly with respect to any of the other outcome variables, although there were trends towards associations between the changes in RBC n-3 LCPUFA and those in BP and CRP. In the present study, we conclude that we could not confirm the fish oil-induced reduction in CVD risk markers after daily consumption of trout with high or low n-3 LCPUFA content. However, trout raised on vegetable-based feed had less pronounced impact on RBC n-3 LCPUFA status.

Authors+Show Affiliations

Department of Human Nutrition, Faculty of Life Sciences, University of Copenhagen, Rolighedsvej 30, DK-1958 Frederiksberg C, Denmark.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20594395

Citation

Hallund, Jesper, et al. "The Effect of Farmed Trout On Cardiovascular Risk Markers in Healthy Men." The British Journal of Nutrition, vol. 104, no. 10, 2010, pp. 1528-36.
Hallund J, Madsen BO, Bügel SH, et al. The effect of farmed trout on cardiovascular risk markers in healthy men. Br J Nutr. 2010;104(10):1528-36.
Hallund, J., Madsen, B. O., Bügel, S. H., Jacobsen, C., Jakobsen, J., Krarup, H., Holm, J., Nielsen, H. H., & Lauritzen, L. (2010). The effect of farmed trout on cardiovascular risk markers in healthy men. The British Journal of Nutrition, 104(10), 1528-36. https://doi.org/10.1017/S0007114510002527
Hallund J, et al. The Effect of Farmed Trout On Cardiovascular Risk Markers in Healthy Men. Br J Nutr. 2010;104(10):1528-36. PubMed PMID: 20594395.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The effect of farmed trout on cardiovascular risk markers in healthy men. AU - Hallund,Jesper, AU - Madsen,Birgitte Overgaard, AU - Bügel,Susanne H, AU - Jacobsen,Charlotte, AU - Jakobsen,Jette, AU - Krarup,Henrik, AU - Holm,Jørgen, AU - Nielsen,Henrik H, AU - Lauritzen,Lotte, Y1 - 2010/07/02/ PY - 2010/7/3/entrez PY - 2010/7/3/pubmed PY - 2010/12/17/medline SP - 1528 EP - 36 JF - The British journal of nutrition JO - Br. J. Nutr. VL - 104 IS - 10 N2 - Increased intake of marine long-chain n-3 PUFA (n-3 LCPUFA) may decrease the risk of CVD and reduce mortality by lowering serum TAG and blood pressure (BP). Furthermore, n-3 LCPUFA may affect novel CVD risk markers related to inflammation and vascular function. The objective of the present study was to examine the effect of farmed trout on novel and traditional CVD risk markers in healthy men, and to evaluate whether this was affected by the aquacultural feed regime. We performed a parallel, 8-week intervention study in which sixty-eight healthy male volunteers were randomised to consume either a daily meal with 150 g farmed trout raised on either marine or vegetable-based feed, or a reference meal containing 150 g chicken. Twenty-four hour BP, pulse wave velocity, augmentation index, fatty acid composition of erythrocyte (RBC), and concentrations of TAG, HDL-cholesterol, LDL-cholesterol, glucose, insulin, C-reactive protein (CRP) and other markers of inflammation were measured at weeks 0 and 8. RBC content of total n-3 LCPUFA, both EPA and DHA, was significantly higher among men consuming trout raised on marine feed compared with men consuming the vegetable-fed trout or chicken. The three intervention groups did not differ significantly with respect to any of the other outcome variables, although there were trends towards associations between the changes in RBC n-3 LCPUFA and those in BP and CRP. In the present study, we conclude that we could not confirm the fish oil-induced reduction in CVD risk markers after daily consumption of trout with high or low n-3 LCPUFA content. However, trout raised on vegetable-based feed had less pronounced impact on RBC n-3 LCPUFA status. SN - 1475-2662 UR - https://www.unboundmedicine.com/medline/citation/20594395/The_effect_of_farmed_trout_on_cardiovascular_risk_markers_in_healthy_men_ L2 - https://www.cambridge.org/core/product/identifier/S0007114510002527/type/journal_article DB - PRIME DP - Unbound Medicine ER -