[Depression and diabetes].Duodecim. 2010; 126(5):521-7.D
11 to 31% of patients with diabetes have depression or clinically significant depressive symptoms. Self-care and compliance of a depressive patient are not always optimal, and depression is independently associated with weakening blood glucose homeostasis. Depression remains undiagnosed in as many as 50 to 75% of cases. Poor glucose homeostasis may exacerbate depression. Treatment of depression in a diabetic patient with the currently most commonly used antidepressants is problematic, since long-term use of these drugs may involve deleterious metabolic effects with regard to diabetes.