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Childhood EEG as a predictor of adult attention-deficit/hyperactivity disorder.
Clin Neurophysiol 2011; 122(1):73-80CN

Abstract

OBJECTIVE

The aim of this study was to determine whether EEG differences exist between children with attention-deficit/hyperactivity disorder (AD/HD) who later outgrow the disorder and those who continue to be symptomatic as adults.

METHODS

Thirty-eight boys, diagnosed with AD/HD as children, were reassessed 11 years later to determine who met criteria for adult AD/HD. At the childhood assessment, an EEG was recorded from the AD/HD group and a control group, during an eyes-closed resting condition. This was analysed for absolute and relative power in the delta, theta, alpha and beta bands, and the theta/beta ratio.

RESULTS

At the childhood assessment, the AD/HD group had an EEG profile typical of the disorder, with increased absolute and relative theta, reduced relative alpha, and increased theta/beta ratio. EEG differences were found between those who outgrew the disorder and those who did not - the adult AD/HD group had greater childhood global relative beta, reduced frontal relative theta, and increased frontal absolute and relative beta.

CONCLUSIONS

These results suggest the existence of specific CNS differences in childhood AD/HD that may be used to predict the developmental course of the disorder.

SIGNIFICANCE

This is the first study to investigate childhood EEG markers of adult AD/HD.

Authors+Show Affiliations

School of Psychology, University of Wollongong, Wollongong 2522, Australia. aclarke@uow.edu.auNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20598939

Citation

Clarke, Adam R., et al. "Childhood EEG as a Predictor of Adult Attention-deficit/hyperactivity Disorder." Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology, vol. 122, no. 1, 2011, pp. 73-80.
Clarke AR, Barry RJ, Dupuy FE, et al. Childhood EEG as a predictor of adult attention-deficit/hyperactivity disorder. Clin Neurophysiol. 2011;122(1):73-80.
Clarke, A. R., Barry, R. J., Dupuy, F. E., McCarthy, R., Selikowitz, M., & Heaven, P. C. (2011). Childhood EEG as a predictor of adult attention-deficit/hyperactivity disorder. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology, 122(1), pp. 73-80. doi:10.1016/j.clinph.2010.05.032.
Clarke AR, et al. Childhood EEG as a Predictor of Adult Attention-deficit/hyperactivity Disorder. Clin Neurophysiol. 2011;122(1):73-80. PubMed PMID: 20598939.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Childhood EEG as a predictor of adult attention-deficit/hyperactivity disorder. AU - Clarke,Adam R, AU - Barry,Robert J, AU - Dupuy,Franca E, AU - McCarthy,Rory, AU - Selikowitz,Mark, AU - Heaven,Patrick C L, Y1 - 2010/07/03/ PY - 2009/05/12/received PY - 2010/05/03/revised PY - 2010/05/30/accepted PY - 2010/7/6/entrez PY - 2010/7/6/pubmed PY - 2011/1/22/medline SP - 73 EP - 80 JF - Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology JO - Clin Neurophysiol VL - 122 IS - 1 N2 - OBJECTIVE: The aim of this study was to determine whether EEG differences exist between children with attention-deficit/hyperactivity disorder (AD/HD) who later outgrow the disorder and those who continue to be symptomatic as adults. METHODS: Thirty-eight boys, diagnosed with AD/HD as children, were reassessed 11 years later to determine who met criteria for adult AD/HD. At the childhood assessment, an EEG was recorded from the AD/HD group and a control group, during an eyes-closed resting condition. This was analysed for absolute and relative power in the delta, theta, alpha and beta bands, and the theta/beta ratio. RESULTS: At the childhood assessment, the AD/HD group had an EEG profile typical of the disorder, with increased absolute and relative theta, reduced relative alpha, and increased theta/beta ratio. EEG differences were found between those who outgrew the disorder and those who did not - the adult AD/HD group had greater childhood global relative beta, reduced frontal relative theta, and increased frontal absolute and relative beta. CONCLUSIONS: These results suggest the existence of specific CNS differences in childhood AD/HD that may be used to predict the developmental course of the disorder. SIGNIFICANCE: This is the first study to investigate childhood EEG markers of adult AD/HD. SN - 1872-8952 UR - https://www.unboundmedicine.com/medline/citation/20598939/Childhood_EEG_as_a_predictor_of_adult_attention_deficit/hyperactivity_disorder_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1388-2457(10)00522-5 DB - PRIME DP - Unbound Medicine ER -