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Hollow fiber-based liquid-liquid-liquid microextraction combined with electrospray ionization-ion mobility spectrometry for the determination of pentazocine in biological samples.
J Chromatogr A. 2010 Aug 06; 1217(32):5173-8.JC

Abstract

A new method based on liquid-liquid-liquid microextraction combined with electrospray ionization-ion mobility spectrometry (LLLME-ESI-IMS) was used for the determination of pentazocine in urine and plasma samples. Experimental parameters which control the performance of LLLME, such as selection of composition of donor and acceptor phase, type of organic solvent, ionic strength of the sample, extraction temperature and extraction time were studied. The limit of detection and relative standard deviation of the method were 2 ng/mL and 5.3%, respectively. The linear calibration ranged from 10 to 500 ng/mL with r(2)=0.998. Pentazocine was successfully determined in urine and plasma samples without any significant matrix effect.

Authors+Show Affiliations

Department of Chemistry, Isfahan University of Technology, Isfahan 84156-83111, Iran. saraji@cc.iut.ac.irNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20605025

Citation

Saraji, Mohammad, et al. "Hollow Fiber-based Liquid-liquid-liquid Microextraction Combined With Electrospray Ionization-ion Mobility Spectrometry for the Determination of Pentazocine in Biological Samples." Journal of Chromatography. A, vol. 1217, no. 32, 2010, pp. 5173-8.
Saraji M, Jafari MT, Sherafatmand H. Hollow fiber-based liquid-liquid-liquid microextraction combined with electrospray ionization-ion mobility spectrometry for the determination of pentazocine in biological samples. J Chromatogr A. 2010;1217(32):5173-8.
Saraji, M., Jafari, M. T., & Sherafatmand, H. (2010). Hollow fiber-based liquid-liquid-liquid microextraction combined with electrospray ionization-ion mobility spectrometry for the determination of pentazocine in biological samples. Journal of Chromatography. A, 1217(32), 5173-8. https://doi.org/10.1016/j.chroma.2010.06.035
Saraji M, Jafari MT, Sherafatmand H. Hollow Fiber-based Liquid-liquid-liquid Microextraction Combined With Electrospray Ionization-ion Mobility Spectrometry for the Determination of Pentazocine in Biological Samples. J Chromatogr A. 2010 Aug 6;1217(32):5173-8. PubMed PMID: 20605025.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hollow fiber-based liquid-liquid-liquid microextraction combined with electrospray ionization-ion mobility spectrometry for the determination of pentazocine in biological samples. AU - Saraji,Mohammad, AU - Jafari,Mohammad Taghi, AU - Sherafatmand,Hossein, Y1 - 2010/06/18/ PY - 2010/01/18/received PY - 2010/05/08/revised PY - 2010/06/11/accepted PY - 2010/7/8/entrez PY - 2010/7/8/pubmed PY - 2010/10/20/medline SP - 5173 EP - 8 JF - Journal of chromatography. A JO - J Chromatogr A VL - 1217 IS - 32 N2 - A new method based on liquid-liquid-liquid microextraction combined with electrospray ionization-ion mobility spectrometry (LLLME-ESI-IMS) was used for the determination of pentazocine in urine and plasma samples. Experimental parameters which control the performance of LLLME, such as selection of composition of donor and acceptor phase, type of organic solvent, ionic strength of the sample, extraction temperature and extraction time were studied. The limit of detection and relative standard deviation of the method were 2 ng/mL and 5.3%, respectively. The linear calibration ranged from 10 to 500 ng/mL with r(2)=0.998. Pentazocine was successfully determined in urine and plasma samples without any significant matrix effect. SN - 1873-3778 UR - https://www.unboundmedicine.com/medline/citation/20605025/Hollow_fiber_based_liquid_liquid_liquid_microextraction_combined_with_electrospray_ionization_ion_mobility_spectrometry_for_the_determination_of_pentazocine_in_biological_samples_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0021-9673(10)00805-8 DB - PRIME DP - Unbound Medicine ER -