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[Axial spondyloarthritis and ankylosing spondylitis].
Duodecim 2010; 126(12):1467-74D

Abstract

Current classification criteria for ankylosing spondylitis do not allow diagnosis before radiographic changes are visible in sacroiliacal joints. The the new axial spondyloarthropathy (SpA) criteria include axial SpA without radiographic changes as well as established ankylosing spondylitis, recognizing them as a continuum of the same disease. This is of major importance as the burden of early SpA is comparable to that of later stage disease. Diagnosis relies on inflammatory MRI findings which is the most significant change compared to earlier criteria. Emerging data on the efficacy of tumor necrosis factor (TNF) alpha blocking therapies already in early but also in established disease have given new promising alternatives for treatment of this often very cumbersome disease, that rarely responds to classic DMARDs.

Authors+Show Affiliations

HYKS:n yleissisätautien ja reumatologian klinikka, PL 340, 00029 HUS.No affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

fin

PubMed ID

20617750

Citation

Nordström, Dan, and Markku Kauppi. "[Axial Spondyloarthritis and Ankylosing Spondylitis]." Duodecim; Laaketieteellinen Aikakauskirja, vol. 126, no. 12, 2010, pp. 1467-74.
Nordström D, Kauppi M. [Axial spondyloarthritis and ankylosing spondylitis]. Duodecim. 2010;126(12):1467-74.
Nordström, D., & Kauppi, M. (2010). [Axial spondyloarthritis and ankylosing spondylitis]. Duodecim; Laaketieteellinen Aikakauskirja, 126(12), pp. 1467-74.
Nordström D, Kauppi M. [Axial Spondyloarthritis and Ankylosing Spondylitis]. Duodecim. 2010;126(12):1467-74. PubMed PMID: 20617750.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Axial spondyloarthritis and ankylosing spondylitis]. AU - Nordström,Dan, AU - Kauppi,Markku, PY - 2010/7/13/entrez PY - 2010/7/14/pubmed PY - 2010/8/14/medline SP - 1467 EP - 74 JF - Duodecim; laaketieteellinen aikakauskirja JO - Duodecim VL - 126 IS - 12 N2 - Current classification criteria for ankylosing spondylitis do not allow diagnosis before radiographic changes are visible in sacroiliacal joints. The the new axial spondyloarthropathy (SpA) criteria include axial SpA without radiographic changes as well as established ankylosing spondylitis, recognizing them as a continuum of the same disease. This is of major importance as the burden of early SpA is comparable to that of later stage disease. Diagnosis relies on inflammatory MRI findings which is the most significant change compared to earlier criteria. Emerging data on the efficacy of tumor necrosis factor (TNF) alpha blocking therapies already in early but also in established disease have given new promising alternatives for treatment of this often very cumbersome disease, that rarely responds to classic DMARDs. SN - 0012-7183 UR - https://www.unboundmedicine.com/medline/citation/20617750/[Axial_spondyloarthritis_and_ankylosing_spondylitis]_ L2 - http://www.diseaseinfosearch.org/result/482 DB - PRIME DP - Unbound Medicine ER -