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Alcohol consumption and the long-term incidence of cataract and cataract surgery: the Blue Mountains Eye Study.
Am J Ophthalmol. 2010 Sep; 150(3):434-440.e1.AJ

Abstract

PURPOSE

To assess whether alcohol consumption is associated with the long-term incidence of cataract or cataract surgery.

DESIGN

Population-based prospective cohort study.

METHODS

A total of 3654 persons aged 49+ years were examined at baseline and 2564 were re-examined after 5 and/or 10 years. Lens photographs were taken at each visit and assessed using the Wisconsin Cataract Grading System by masked graders. An interviewer-administered questionnaire was used to collect information on alcohol consumption.

RESULTS

No significant associations were observed between alcohol consumption and long-term risk of nuclear, cortical, and posterior subcapsular cataract. However, after adjusting for age, gender, smoking, diabetes, myopia, socioeconomic status, and steroid use, total alcohol consumption of over 2 standard drinks per day was associated with a significantly increased likelihood of cataract surgery, when compared to total daily alcohol consumption of 1 to 2 standard drinks (adjusted odds ratio [OR] 2.10, 95% confidence interval [CI] 1.16-3.81). Abstinence from alcohol was also associated with increased likelihood of cataract surgery when compared to a total alcohol consumption of 1 to 2 standard drinks per day (adjusted OR 2.36, 95% CI 1.25-4.46).

CONCLUSION

A U-shaped association of alcohol consumption with the long-term risk of cataract surgery was found in this older cohort: moderate consumption was associated with 50% lower cataract surgery incidence, compared either to abstinence or heavy alcohol consumption.

Authors+Show Affiliations

Centre for Vision Research, Department of Ophthalmology and Westmead Millennium Institute, University of Sydney, Sydney, Australia.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20619390

Citation

Kanthan, Gowri L., et al. "Alcohol Consumption and the Long-term Incidence of Cataract and Cataract Surgery: the Blue Mountains Eye Study." American Journal of Ophthalmology, vol. 150, no. 3, 2010, pp. 434-440.e1.
Kanthan GL, Mitchell P, Burlutsky G, et al. Alcohol consumption and the long-term incidence of cataract and cataract surgery: the Blue Mountains Eye Study. Am J Ophthalmol. 2010;150(3):434-440.e1.
Kanthan, G. L., Mitchell, P., Burlutsky, G., & Wang, J. J. (2010). Alcohol consumption and the long-term incidence of cataract and cataract surgery: the Blue Mountains Eye Study. American Journal of Ophthalmology, 150(3), 434-e1. https://doi.org/10.1016/j.ajo.2010.04.020
Kanthan GL, et al. Alcohol Consumption and the Long-term Incidence of Cataract and Cataract Surgery: the Blue Mountains Eye Study. Am J Ophthalmol. 2010;150(3):434-440.e1. PubMed PMID: 20619390.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alcohol consumption and the long-term incidence of cataract and cataract surgery: the Blue Mountains Eye Study. AU - Kanthan,Gowri L, AU - Mitchell,Paul, AU - Burlutsky,George, AU - Wang,Jie Jin, Y1 - 2010/07/08/ PY - 2009/12/31/received PY - 2010/04/20/revised PY - 2010/04/21/accepted PY - 2010/7/13/entrez PY - 2010/7/14/pubmed PY - 2010/9/3/medline SP - 434 EP - 440.e1 JF - American journal of ophthalmology JO - Am. J. Ophthalmol. VL - 150 IS - 3 N2 - PURPOSE: To assess whether alcohol consumption is associated with the long-term incidence of cataract or cataract surgery. DESIGN: Population-based prospective cohort study. METHODS: A total of 3654 persons aged 49+ years were examined at baseline and 2564 were re-examined after 5 and/or 10 years. Lens photographs were taken at each visit and assessed using the Wisconsin Cataract Grading System by masked graders. An interviewer-administered questionnaire was used to collect information on alcohol consumption. RESULTS: No significant associations were observed between alcohol consumption and long-term risk of nuclear, cortical, and posterior subcapsular cataract. However, after adjusting for age, gender, smoking, diabetes, myopia, socioeconomic status, and steroid use, total alcohol consumption of over 2 standard drinks per day was associated with a significantly increased likelihood of cataract surgery, when compared to total daily alcohol consumption of 1 to 2 standard drinks (adjusted odds ratio [OR] 2.10, 95% confidence interval [CI] 1.16-3.81). Abstinence from alcohol was also associated with increased likelihood of cataract surgery when compared to a total alcohol consumption of 1 to 2 standard drinks per day (adjusted OR 2.36, 95% CI 1.25-4.46). CONCLUSION: A U-shaped association of alcohol consumption with the long-term risk of cataract surgery was found in this older cohort: moderate consumption was associated with 50% lower cataract surgery incidence, compared either to abstinence or heavy alcohol consumption. SN - 1879-1891 UR - https://www.unboundmedicine.com/medline/citation/20619390/Alcohol_consumption_and_the_long_term_incidence_of_cataract_and_cataract_surgery:_the_Blue_Mountains_Eye_Study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9394(10)00304-1 DB - PRIME DP - Unbound Medicine ER -