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Skin cancer incidence is highly associated with ultraviolet-B radiation history.
Int J Hyg Environ Health 2010; 213(5):359-68IJ

Abstract

Recently, the increased amount of ultraviolet-B (UV-B) exposure due to ozone depletion has been found to be associated with increased incidence of skin cancer across the world. The quantification of individual, regional, and historical UV exposure directly affects establishment of the association between skin cancer and UV exposure, but accurate assessment and measurement have been challenging for decades. As a sequence, cumulative studies using different metrics reported conflicting results on whether UV radiation, including sunburns, early childhood sun exposure, and chronic exposure, increases melanoma risk. This paper aims to establish the relationship between UV-B and melanoma incidence across the continental U.S. using an ecological approach that incorporate more accurate UV-B exposure measured by the National Aeronautical and Space Administration Nimbus-7 total ozone mapping spectrometer, and the United State Department of Agriculture ground-based network. Using statistical linear mixed models, we found strong positive associations between the skin cancer and the past UV exposure or the past cumulative 3-year UV exposure 3 or 4 years ago. UV has regional distributions and its regional effects on the skin cancer incidence are still significant after adjusting the effect of UV exposure. Research findings yield deepened understanding of spatiotemporal distribution of melanoma incidence rates and a greater appreciation for the complexity and heterogeneity of melanoma risk factors especially the UV-B exposure at different temporal and spatial scales.

Authors+Show Affiliations

Department of Civil, Environmental, and Construction Engineering, University of Central Florida, Orlando, FL, USA. nchang@mail.ucf.eduNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Multicenter Study

Language

eng

PubMed ID

20619731

Citation

Chang, Ni-Bin, et al. "Skin Cancer Incidence Is Highly Associated With ultraviolet-B Radiation History." International Journal of Hygiene and Environmental Health, vol. 213, no. 5, 2010, pp. 359-68.
Chang NB, Feng R, Gao Z, et al. Skin cancer incidence is highly associated with ultraviolet-B radiation history. Int J Hyg Environ Health. 2010;213(5):359-68.
Chang, N. B., Feng, R., Gao, Z., & Gao, W. (2010). Skin cancer incidence is highly associated with ultraviolet-B radiation history. International Journal of Hygiene and Environmental Health, 213(5), pp. 359-68. doi:10.1016/j.ijheh.2010.06.006.
Chang NB, et al. Skin Cancer Incidence Is Highly Associated With ultraviolet-B Radiation History. Int J Hyg Environ Health. 2010;213(5):359-68. PubMed PMID: 20619731.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Skin cancer incidence is highly associated with ultraviolet-B radiation history. AU - Chang,Ni-Bin, AU - Feng,Rui, AU - Gao,Zhiqiang, AU - Gao,Wei, Y1 - 2010/07/08/ PY - 2010/02/28/received PY - 2010/05/30/revised PY - 2010/06/09/accepted PY - 2010/7/13/entrez PY - 2010/7/14/pubmed PY - 2010/12/14/medline SP - 359 EP - 68 JF - International journal of hygiene and environmental health JO - Int J Hyg Environ Health VL - 213 IS - 5 N2 - Recently, the increased amount of ultraviolet-B (UV-B) exposure due to ozone depletion has been found to be associated with increased incidence of skin cancer across the world. The quantification of individual, regional, and historical UV exposure directly affects establishment of the association between skin cancer and UV exposure, but accurate assessment and measurement have been challenging for decades. As a sequence, cumulative studies using different metrics reported conflicting results on whether UV radiation, including sunburns, early childhood sun exposure, and chronic exposure, increases melanoma risk. This paper aims to establish the relationship between UV-B and melanoma incidence across the continental U.S. using an ecological approach that incorporate more accurate UV-B exposure measured by the National Aeronautical and Space Administration Nimbus-7 total ozone mapping spectrometer, and the United State Department of Agriculture ground-based network. Using statistical linear mixed models, we found strong positive associations between the skin cancer and the past UV exposure or the past cumulative 3-year UV exposure 3 or 4 years ago. UV has regional distributions and its regional effects on the skin cancer incidence are still significant after adjusting the effect of UV exposure. Research findings yield deepened understanding of spatiotemporal distribution of melanoma incidence rates and a greater appreciation for the complexity and heterogeneity of melanoma risk factors especially the UV-B exposure at different temporal and spatial scales. SN - 1618-131X UR - https://www.unboundmedicine.com/medline/citation/20619731/Skin_cancer_incidence_is_highly_associated_with_ultraviolet_B_radiation_history_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1438-4639(10)00084-2 DB - PRIME DP - Unbound Medicine ER -