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The effects of alcohol and drug abuse on the skin.

Abstract

Skin changes associated with alcohol and drug abuse can be the earliest clinical manifestation of these disorders. The signs associated with these conditions may be distinctive and easily recognizable. Alcohol abuse can present with jaundice, pruritus, hyperpigmentation, and urticaria. Commonly associated vascular changes include spider telangiectasias, angiomas, caput medusas, flushing, and palmar erythema. Disease states related to alcohol abuse include psoriasis, porphyria cutanea tarda, and nutritional deficiencies. Alcohol abuse may predispose to the development of carcinomas of the skin, oropharynx, liver, pancreas, and breast. Cutaneous signs of drug abuse include skin granulomas, ulcerations, and recurrent infections. Specifically, oral disease and tooth decay are examples of stigmata often associated with methamphetamine abuse, a popular and inexpensive drug now on the scene. By being cognizant of these cutaneous markers of alcohol and drug abuse, dermatologists are often in the unique position of being able to recognize these changes, prompting early diagnosis and intervention, hopefully resulting in a better clinical outcome for these troubled patients and their families.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Dermatology and Cutaneous Surgery, University of South Florida College of Medicine, 12901 Bruce B. Downs Blvd, MDC 79, Tampa, FL 33612, USA.

    ,

    Source

    MeSH

    Alcoholism
    Female
    Humans
    Male
    Risk Factors
    Skin
    Skin Diseases
    Substance-Related Disorders

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    20620755

    Citation

    Liu, Stephanie W., et al. "The Effects of Alcohol and Drug Abuse On the Skin." Clinics in Dermatology, vol. 28, no. 4, 2010, pp. 391-9.
    Liu SW, Lien MH, Fenske NA. The effects of alcohol and drug abuse on the skin. Clin Dermatol. 2010;28(4):391-9.
    Liu, S. W., Lien, M. H., & Fenske, N. A. (2010). The effects of alcohol and drug abuse on the skin. Clinics in Dermatology, 28(4), pp. 391-9. doi:10.1016/j.clindermatol.2010.03.024.
    Liu SW, Lien MH, Fenske NA. The Effects of Alcohol and Drug Abuse On the Skin. Clin Dermatol. 2010;28(4):391-9. PubMed PMID: 20620755.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - The effects of alcohol and drug abuse on the skin. AU - Liu,Stephanie W, AU - Lien,Mary H, AU - Fenske,Neil Alan, PY - 2010/7/13/entrez PY - 2010/7/14/pubmed PY - 2010/10/21/medline SP - 391 EP - 9 JF - Clinics in dermatology JO - Clin. Dermatol. VL - 28 IS - 4 N2 - Skin changes associated with alcohol and drug abuse can be the earliest clinical manifestation of these disorders. The signs associated with these conditions may be distinctive and easily recognizable. Alcohol abuse can present with jaundice, pruritus, hyperpigmentation, and urticaria. Commonly associated vascular changes include spider telangiectasias, angiomas, caput medusas, flushing, and palmar erythema. Disease states related to alcohol abuse include psoriasis, porphyria cutanea tarda, and nutritional deficiencies. Alcohol abuse may predispose to the development of carcinomas of the skin, oropharynx, liver, pancreas, and breast. Cutaneous signs of drug abuse include skin granulomas, ulcerations, and recurrent infections. Specifically, oral disease and tooth decay are examples of stigmata often associated with methamphetamine abuse, a popular and inexpensive drug now on the scene. By being cognizant of these cutaneous markers of alcohol and drug abuse, dermatologists are often in the unique position of being able to recognize these changes, prompting early diagnosis and intervention, hopefully resulting in a better clinical outcome for these troubled patients and their families. SN - 1879-1131 UR - https://www.unboundmedicine.com/medline/citation/20620755/The_effects_of_alcohol_and_drug_abuse_on_the_skin_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0738-081X(10)00048-9 DB - PRIME DP - Unbound Medicine ER -