Nutrition and aging skin: sugar and glycation.Clin Dermatol. 2010 Jul-Aug; 28(4):409-11.CD
Abstract
The effect of sugars on aging skin is governed by the simple act of covalently cross-linking two collagen fibers, which renders both of them incapable of easy repair. Glucose and fructose link the amino acids present in the collagen and elastin that support the dermis, producing advanced glycation end products or "AGEs." This process is accelerated in all body tissues when sugar is elevated and is further stimulated by ultraviolet light in the skin. The effect on vascular, renal, retinal, coronary, and cutaneous tissues is being defined, as are methods of reducing the glycation load through careful diet and use of supplements.
Links
MeSH
Pub Type(s)
Journal Article
Language
eng
PubMed ID
20620757
Citation
Danby, F William. "Nutrition and Aging Skin: Sugar and Glycation." Clinics in Dermatology, vol. 28, no. 4, 2010, pp. 409-11.
Danby FW. Nutrition and aging skin: sugar and glycation. Clin Dermatol. 2010;28(4):409-11.
Danby, F. W. (2010). Nutrition and aging skin: sugar and glycation. Clinics in Dermatology, 28(4), 409-11. https://doi.org/10.1016/j.clindermatol.2010.03.018
Danby FW. Nutrition and Aging Skin: Sugar and Glycation. Clin Dermatol. 2010 Jul-Aug;28(4):409-11. PubMed PMID: 20620757.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Nutrition and aging skin: sugar and glycation.
A1 - Danby,F William,
PY - 2010/7/13/entrez
PY - 2010/7/14/pubmed
PY - 2010/10/21/medline
SP - 409
EP - 11
JF - Clinics in dermatology
JO - Clin Dermatol
VL - 28
IS - 4
N2 - The effect of sugars on aging skin is governed by the simple act of covalently cross-linking two collagen fibers, which renders both of them incapable of easy repair. Glucose and fructose link the amino acids present in the collagen and elastin that support the dermis, producing advanced glycation end products or "AGEs." This process is accelerated in all body tissues when sugar is elevated and is further stimulated by ultraviolet light in the skin. The effect on vascular, renal, retinal, coronary, and cutaneous tissues is being defined, as are methods of reducing the glycation load through careful diet and use of supplements.
SN - 1879-1131
UR - https://www.unboundmedicine.com/medline/citation/20620757/Nutrition_and_aging_skin:_sugar_and_glycation_
L2 - https://linkinghub.elsevier.com/retrieve/pii/S0738-081X(10)00042-8
DB - PRIME
DP - Unbound Medicine
ER -