Tags

Type your tag names separated by a space and hit enter

Antioxidant activity of Nepeta nuda L. ssp. nuda essential oil rich in nepetalactones from Greece.
J Med Food. 2010 Oct; 13(5):1176-81.JM

Abstract

Essential oils from air-dried leaves and verticillasters of Nepeta nuda ssp. nuda from Greece were analyzed by means of gas chromatography-flame ionization detection and gas chromatography-mass spectrometry. The dominant constituent in the verticillaster oils was 4aα,7α,7aβ-nepetalactone (75.7%). The main metabolites of the leaf oil were 1,8-cineole (16.7%), 4aα,7α,7aβ-nepetalactone (24.7%), and caryophyllene oxide (16.3%). The oils were examined for their antioxidant activity. Neutralization of stable 2,2-diphenyl-1-picrylhydrazyl radical ranged from 10.83% (2.50 μg/mL) to 58.64% (50.00 μg/mL) for verticillaster oil and from 6.25% (2.50 μg/mL) to 57.79% (50.00 μg/mL) for leaf oil. The essential oil from verticillasters had significant effects on lipid peroxidation (in the range of 41.18-59.23%), compared to tert-butylated hydroxytoluene (37.04%). In contrast, the essential oil from leaves exhibited pro-oxidant activity at the highest concentration applied.

Authors+Show Affiliations

Department of Pharmacognosy and Chemistry of Natural Products, School of Pharmacy, University of Athens, Athens, Greece.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20626246

Citation

Gkinis, George, et al. "Antioxidant Activity of Nepeta Nuda L. Ssp. Nuda Essential Oil Rich in Nepetalactones From Greece." Journal of Medicinal Food, vol. 13, no. 5, 2010, pp. 1176-81.
Gkinis G, Bozin B, Mimica-Dukic N, et al. Antioxidant activity of Nepeta nuda L. ssp. nuda essential oil rich in nepetalactones from Greece. J Med Food. 2010;13(5):1176-81.
Gkinis, G., Bozin, B., Mimica-Dukic, N., & Tzakou, O. (2010). Antioxidant activity of Nepeta nuda L. ssp. nuda essential oil rich in nepetalactones from Greece. Journal of Medicinal Food, 13(5), 1176-81. https://doi.org/10.1089/jmf.2009.0218
Gkinis G, et al. Antioxidant Activity of Nepeta Nuda L. Ssp. Nuda Essential Oil Rich in Nepetalactones From Greece. J Med Food. 2010;13(5):1176-81. PubMed PMID: 20626246.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antioxidant activity of Nepeta nuda L. ssp. nuda essential oil rich in nepetalactones from Greece. AU - Gkinis,George, AU - Bozin,Biljana, AU - Mimica-Dukic,Neda, AU - Tzakou,Olga, PY - 2010/7/15/entrez PY - 2010/7/16/pubmed PY - 2011/1/19/medline SP - 1176 EP - 81 JF - Journal of medicinal food JO - J Med Food VL - 13 IS - 5 N2 - Essential oils from air-dried leaves and verticillasters of Nepeta nuda ssp. nuda from Greece were analyzed by means of gas chromatography-flame ionization detection and gas chromatography-mass spectrometry. The dominant constituent in the verticillaster oils was 4aα,7α,7aβ-nepetalactone (75.7%). The main metabolites of the leaf oil were 1,8-cineole (16.7%), 4aα,7α,7aβ-nepetalactone (24.7%), and caryophyllene oxide (16.3%). The oils were examined for their antioxidant activity. Neutralization of stable 2,2-diphenyl-1-picrylhydrazyl radical ranged from 10.83% (2.50 μg/mL) to 58.64% (50.00 μg/mL) for verticillaster oil and from 6.25% (2.50 μg/mL) to 57.79% (50.00 μg/mL) for leaf oil. The essential oil from verticillasters had significant effects on lipid peroxidation (in the range of 41.18-59.23%), compared to tert-butylated hydroxytoluene (37.04%). In contrast, the essential oil from leaves exhibited pro-oxidant activity at the highest concentration applied. SN - 1557-7600 UR - https://www.unboundmedicine.com/medline/citation/20626246/Antioxidant_activity_of_Nepeta_nuda_L__ssp__nuda_essential_oil_rich_in_nepetalactones_from_Greece_ L2 - https://www.liebertpub.com/doi/10.1089/jmf.2009.0218?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -