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Newly described translocation (18;19)(q23;q13.2) in abdominal wall soft-tissue tumor resembling Ewing sarcoma/primitive neuroectodermal tumor.
Cancer Genet Cytogenet. 2010 Aug; 201(1):1-5.CG

Abstract

From a morphologic standpoint, Ewing sarcoma (EWS) is one of a number of pediatric malignancies that are characterized by sheets of small, round, blue cells. Ewing sarcoma can usually be differentiated from other small round blue cell tumors by the presence of a gene rearrangement having a consistent breakpoint within the Ewing sarcoma gene (EWSR1) at 22q12. Although the most common translocation partner is FLI1, located at 11q24, there is a growing list of alternate rearrangements involving different loci. We describe the first example of a soft-tissue sarcoma morphologically and immunohistochemically similar to Ewing sarcoma, but with a novel t(18;19)(q23;q13.2).

Authors+Show Affiliations

Department of Orthopedics, Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

20633761

Citation

Riccardi, Gina F., et al. "Newly Described Translocation (18;19)(q23;q13.2) in Abdominal Wall Soft-tissue Tumor Resembling Ewing Sarcoma/primitive Neuroectodermal Tumor." Cancer Genetics and Cytogenetics, vol. 201, no. 1, 2010, pp. 1-5.
Riccardi GF, Stein C, de la Roza G, et al. Newly described translocation (18;19)(q23;q13.2) in abdominal wall soft-tissue tumor resembling Ewing sarcoma/primitive neuroectodermal tumor. Cancer Genet Cytogenet. 2010;201(1):1-5.
Riccardi, G. F., Stein, C., de la Roza, G., & Damron, T. A. (2010). Newly described translocation (18;19)(q23;q13.2) in abdominal wall soft-tissue tumor resembling Ewing sarcoma/primitive neuroectodermal tumor. Cancer Genetics and Cytogenetics, 201(1), 1-5. https://doi.org/10.1016/j.cancergencyto.2010.04.012
Riccardi GF, et al. Newly Described Translocation (18;19)(q23;q13.2) in Abdominal Wall Soft-tissue Tumor Resembling Ewing Sarcoma/primitive Neuroectodermal Tumor. Cancer Genet Cytogenet. 2010;201(1):1-5. PubMed PMID: 20633761.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Newly described translocation (18;19)(q23;q13.2) in abdominal wall soft-tissue tumor resembling Ewing sarcoma/primitive neuroectodermal tumor. AU - Riccardi,Gina F, AU - Stein,Constance, AU - de la Roza,Gustavo, AU - Damron,Timothy A, PY - 2010/01/19/received PY - 2010/04/15/revised PY - 2010/04/18/accepted PY - 2010/7/17/entrez PY - 2010/7/17/pubmed PY - 2010/7/30/medline SP - 1 EP - 5 JF - Cancer genetics and cytogenetics JO - Cancer Genet. Cytogenet. VL - 201 IS - 1 N2 - From a morphologic standpoint, Ewing sarcoma (EWS) is one of a number of pediatric malignancies that are characterized by sheets of small, round, blue cells. Ewing sarcoma can usually be differentiated from other small round blue cell tumors by the presence of a gene rearrangement having a consistent breakpoint within the Ewing sarcoma gene (EWSR1) at 22q12. Although the most common translocation partner is FLI1, located at 11q24, there is a growing list of alternate rearrangements involving different loci. We describe the first example of a soft-tissue sarcoma morphologically and immunohistochemically similar to Ewing sarcoma, but with a novel t(18;19)(q23;q13.2). SN - 1873-4456 UR - https://www.unboundmedicine.com/medline/citation/20633761/Newly_described_translocation__18/primitive_neuroectodermal_tumor_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0165-4608(10)00164-0 DB - PRIME DP - Unbound Medicine ER -