Newly described translocation (18;19)(q23;q13.2) in abdominal wall soft-tissue tumor resembling Ewing sarcoma/primitive neuroectodermal tumor.Cancer Genet Cytogenet. 2010 Aug; 201(1):1-5.CG
Abstract
From a morphologic standpoint, Ewing sarcoma (EWS) is one of a number of pediatric malignancies that are characterized by sheets of small, round, blue cells. Ewing sarcoma can usually be differentiated from other small round blue cell tumors by the presence of a gene rearrangement having a consistent breakpoint within the Ewing sarcoma gene (EWSR1) at 22q12. Although the most common translocation partner is FLI1, located at 11q24, there is a growing list of alternate rearrangements involving different loci. We describe the first example of a soft-tissue sarcoma morphologically and immunohistochemically similar to Ewing sarcoma, but with a novel t(18;19)(q23;q13.2).
Links
MeSH
Abdominal NeoplasmsAdolescentCalmodulin-Binding ProteinsChromosomes, Human, Pair 18Chromosomes, Human, Pair 19HumansIn Situ Hybridization, FluorescenceKaryotypingMaleNeuroectodermal TumorsProto-Oncogene Protein c-fli-1RNA-Binding Protein EWSRNA-Binding ProteinsSarcoma, EwingSoft Tissue NeoplasmsTranslocation, Genetic
Pub Type(s)
Case Reports
Journal Article
Language
eng
PubMed ID
20633761
Citation
Riccardi, Gina F., et al. "Newly Described Translocation (18;19)(q23;q13.2) in Abdominal Wall Soft-tissue Tumor Resembling Ewing Sarcoma/primitive Neuroectodermal Tumor." Cancer Genetics and Cytogenetics, vol. 201, no. 1, 2010, pp. 1-5.
Riccardi GF, Stein C, de la Roza G, et al. Newly described translocation (18;19)(q23;q13.2) in abdominal wall soft-tissue tumor resembling Ewing sarcoma/primitive neuroectodermal tumor. Cancer Genet Cytogenet. 2010;201(1):1-5.
Riccardi, G. F., Stein, C., de la Roza, G., & Damron, T. A. (2010). Newly described translocation (18;19)(q23;q13.2) in abdominal wall soft-tissue tumor resembling Ewing sarcoma/primitive neuroectodermal tumor. Cancer Genetics and Cytogenetics, 201(1), 1-5. https://doi.org/10.1016/j.cancergencyto.2010.04.012
Riccardi GF, et al. Newly Described Translocation (18;19)(q23;q13.2) in Abdominal Wall Soft-tissue Tumor Resembling Ewing Sarcoma/primitive Neuroectodermal Tumor. Cancer Genet Cytogenet. 2010;201(1):1-5. PubMed PMID: 20633761.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Newly described translocation (18;19)(q23;q13.2) in abdominal wall soft-tissue tumor resembling Ewing sarcoma/primitive neuroectodermal tumor.
AU - Riccardi,Gina F,
AU - Stein,Constance,
AU - de la Roza,Gustavo,
AU - Damron,Timothy A,
PY - 2010/01/19/received
PY - 2010/04/15/revised
PY - 2010/04/18/accepted
PY - 2010/7/17/entrez
PY - 2010/7/17/pubmed
PY - 2010/7/30/medline
SP - 1
EP - 5
JF - Cancer genetics and cytogenetics
JO - Cancer Genet. Cytogenet.
VL - 201
IS - 1
N2 - From a morphologic standpoint, Ewing sarcoma (EWS) is one of a number of pediatric malignancies that are characterized by sheets of small, round, blue cells. Ewing sarcoma can usually be differentiated from other small round blue cell tumors by the presence of a gene rearrangement having a consistent breakpoint within the Ewing sarcoma gene (EWSR1) at 22q12. Although the most common translocation partner is FLI1, located at 11q24, there is a growing list of alternate rearrangements involving different loci. We describe the first example of a soft-tissue sarcoma morphologically and immunohistochemically similar to Ewing sarcoma, but with a novel t(18;19)(q23;q13.2).
SN - 1873-4456
UR - https://www.unboundmedicine.com/medline/citation/20633761/Newly_described_translocation__18/primitive_neuroectodermal_tumor_
L2 - https://linkinghub.elsevier.com/retrieve/pii/S0165-4608(10)00164-0
DB - PRIME
DP - Unbound Medicine
ER -
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