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Prolonged coma in a child due to hashish ingestion with quantitation of THC metabolites in urine.
J Emerg Med 2011; 41(3):e69-71JE

Abstract

BACKGROUND

Cannabinoid-containing substances are commonly abused worldwide. Significant toxicity from these substances is uncommon in adults but can result in significant symptoms in children; these symptoms are usually short-lived.

OBJECTIVES

To report a case of prolonged mental status alteration of more than 2 days in a child who ingested hashish.

CASE REPORT

A 14-month-old child presented comatose to a pediatric emergency department after ingestion of hashish; she did not regain consciousness for more than 48 h. Quantitative testing of the child's urine for a tetrahydrocannabinol metabolite revealed a markedly elevated level, the decline of which coincided with the child's clinical improvement.

CONCLUSIONS

Significant ingestion of cannabinoid-containing substances is capable of causing prolonged symptoms (including coma) in children.

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    Authors+Show Affiliations

    Carstairs SD
    Department of Emergency Medicine, Division of Medical Toxicology, University of California San Diego, San Diego, California, USA.
    Fujinaka MK
    No affiliation info available
    Keeney GE
    No affiliation info available
    Ly BT
    No affiliation info available

    MeSH

    Administration, OralBiomarkersCannabisComaDronabinolFemaleHumansInfant

    Pub Type(s)

    Case Reports
    Journal Article

    Language

    eng

    PubMed ID

    20634020

    Citation

    Carstairs, Shaun D., et al. "Prolonged Coma in a Child Due to Hashish Ingestion With Quantitation of THC Metabolites in Urine." The Journal of Emergency Medicine, vol. 41, no. 3, 2011, pp. e69-71.
    Carstairs SD, Fujinaka MK, Keeney GE, et al. Prolonged coma in a child due to hashish ingestion with quantitation of THC metabolites in urine. J Emerg Med. 2011;41(3):e69-71.
    Carstairs, S. D., Fujinaka, M. K., Keeney, G. E., & Ly, B. T. (2011). Prolonged coma in a child due to hashish ingestion with quantitation of THC metabolites in urine. The Journal of Emergency Medicine, 41(3), pp. e69-71. doi:10.1016/j.jemermed.2010.05.032.
    Carstairs SD, et al. Prolonged Coma in a Child Due to Hashish Ingestion With Quantitation of THC Metabolites in Urine. J Emerg Med. 2011;41(3):e69-71. PubMed PMID: 20634020.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Prolonged coma in a child due to hashish ingestion with quantitation of THC metabolites in urine. AU - Carstairs,Shaun D, AU - Fujinaka,Michael K, AU - Keeney,Grant E, AU - Ly,Binh T, Y1 - 2010/07/15/ PY - 2010/01/25/received PY - 2010/04/17/revised PY - 2010/05/18/accepted PY - 2010/7/17/entrez PY - 2010/7/17/pubmed PY - 2011/12/15/medline SP - e69 EP - 71 JF - The Journal of emergency medicine JO - J Emerg Med VL - 41 IS - 3 N2 - BACKGROUND: Cannabinoid-containing substances are commonly abused worldwide. Significant toxicity from these substances is uncommon in adults but can result in significant symptoms in children; these symptoms are usually short-lived. OBJECTIVES: To report a case of prolonged mental status alteration of more than 2 days in a child who ingested hashish. CASE REPORT: A 14-month-old child presented comatose to a pediatric emergency department after ingestion of hashish; she did not regain consciousness for more than 48 h. Quantitative testing of the child's urine for a tetrahydrocannabinol metabolite revealed a markedly elevated level, the decline of which coincided with the child's clinical improvement. CONCLUSIONS: Significant ingestion of cannabinoid-containing substances is capable of causing prolonged symptoms (including coma) in children. SN - 0736-4679 UR - https://www.unboundmedicine.com/medline/citation/20634020/abstract/Prolonged_coma_in_a_child_due_to_hashish_ingestion_with_quantitation_of_THC_metabolites_in_urine_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0736-4679(10)00406-3 DB - PRIME DP - Unbound Medicine ER -