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Prolonged coma in a child due to hashish ingestion with quantitation of THC metabolites in urine.

Abstract

BACKGROUND

Cannabinoid-containing substances are commonly abused worldwide. Significant toxicity from these substances is uncommon in adults but can result in significant symptoms in children; these symptoms are usually short-lived.

OBJECTIVES

To report a case of prolonged mental status alteration of more than 2 days in a child who ingested hashish.

CASE REPORT

A 14-month-old child presented comatose to a pediatric emergency department after ingestion of hashish; she did not regain consciousness for more than 48 h. Quantitative testing of the child's urine for a tetrahydrocannabinol metabolite revealed a markedly elevated level, the decline of which coincided with the child's clinical improvement.

CONCLUSIONS

Significant ingestion of cannabinoid-containing substances is capable of causing prolonged symptoms (including coma) in children.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Emergency Medicine, Division of Medical Toxicology, University of California San Diego, San Diego, California, USA.

    , ,

    Source

    The Journal of emergency medicine 41:3 2011 Sep pg e69-71

    MeSH

    Administration, Oral
    Biomarkers
    Cannabis
    Coma
    Dronabinol
    Female
    Humans
    Infant

    Pub Type(s)

    Case Reports
    Journal Article

    Language

    eng

    PubMed ID

    20634020

    Citation

    * When formatting your citation, note that all book, journal, and database titles should be italicized* Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Prolonged coma in a child due to hashish ingestion with quantitation of THC metabolites in urine. AU - Carstairs,Shaun D, AU - Fujinaka,Michael K, AU - Keeney,Grant E, AU - Ly,Binh T, Y1 - 2010/07/15/ PY - 2010/01/25/received PY - 2010/04/17/revised PY - 2010/05/18/accepted PY - 2010/7/17/entrez PY - 2010/7/17/pubmed PY - 2011/12/15/medline SP - e69 EP - 71 JF - The Journal of emergency medicine JO - J Emerg Med VL - 41 IS - 3 N2 - BACKGROUND: Cannabinoid-containing substances are commonly abused worldwide. Significant toxicity from these substances is uncommon in adults but can result in significant symptoms in children; these symptoms are usually short-lived. OBJECTIVES: To report a case of prolonged mental status alteration of more than 2 days in a child who ingested hashish. CASE REPORT: A 14-month-old child presented comatose to a pediatric emergency department after ingestion of hashish; she did not regain consciousness for more than 48 h. Quantitative testing of the child's urine for a tetrahydrocannabinol metabolite revealed a markedly elevated level, the decline of which coincided with the child's clinical improvement. CONCLUSIONS: Significant ingestion of cannabinoid-containing substances is capable of causing prolonged symptoms (including coma) in children. SN - 0736-4679 UR - https://www.unboundmedicine.com/medline/citation/20634020/abstract/Prolonged_coma_in_a_child_due_to_hashish_ingestion_with_quantitation_of_THC_metabolites_in_urine_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0736-4679(10)00406-3 DB - PRIME DP - Unbound Medicine ER -