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Prevalence of and risk factors for primary open-angle glaucoma in central Sri Lanka: the Kandy eye study.
Ophthalmic Epidemiol. 2010 Aug; 17(4):211-6.OE

Abstract

PURPOSE

To report the prevalence and risk factors associated with primary open-angle glaucoma (POAG) in the Kandy district of central Sri Lanka.

METHODS

A cross-sectional, population-based ophthalmic survey of the inhabitants >or= 40 years of age from villages in the Kandy District, Sri Lanka was conducted. Selection was randomized using a cluster sampling process; 1721 eligible participants were identified, 1375 participated in the study and sufficient examination data to diagnose glaucoma in at least one eye was obtained in 1244 participants. A detailed ophthalmic history and examination including ocular biometry was made of each participant. Primary open-angle glaucoma was classified into three levels according to diagnostic evidence.

RESULTS

The overall prevalence of POAG was 2.3% (95% CI 1.5-3.2). In the univariate analyses, increasing age (P = 0.001), intraocular pressure (IOP) (P < 0.001), myopia (P < 0.001) and axial length (P = 0.003) were significantly associated with POAG. In the multivariate analysis, age (P = 0.001), mean IOP (P < 0.001) and mean axial length (P = 0.008) were significant risk factors of POAG.

CONCLUSIONS

The prevalence of POAG in the population aged >or=40 years in central Sri Lanka was 2.3%. POAG in this population was independently associated with increasing age, IOP and axial length.

Authors+Show Affiliations

University of Adelaide, Adelaide, Australia. daviditsia@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20642343

Citation

Sia, David I T., et al. "Prevalence of and Risk Factors for Primary Open-angle Glaucoma in Central Sri Lanka: the Kandy Eye Study." Ophthalmic Epidemiology, vol. 17, no. 4, 2010, pp. 211-6.
Sia DI, Edussuriya K, Sennanayake S, et al. Prevalence of and risk factors for primary open-angle glaucoma in central Sri Lanka: the Kandy eye study. Ophthalmic Epidemiol. 2010;17(4):211-6.
Sia, D. I., Edussuriya, K., Sennanayake, S., Senaratne, T., Selva, D., & Casson, R. J. (2010). Prevalence of and risk factors for primary open-angle glaucoma in central Sri Lanka: the Kandy eye study. Ophthalmic Epidemiology, 17(4), 211-6. https://doi.org/10.3109/09286586.2010.483753
Sia DI, et al. Prevalence of and Risk Factors for Primary Open-angle Glaucoma in Central Sri Lanka: the Kandy Eye Study. Ophthalmic Epidemiol. 2010;17(4):211-6. PubMed PMID: 20642343.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of and risk factors for primary open-angle glaucoma in central Sri Lanka: the Kandy eye study. AU - Sia,David I T, AU - Edussuriya,Kapila, AU - Sennanayake,Saman, AU - Senaratne,Tissa, AU - Selva,Dinesh, AU - Casson,Robert J, PY - 2010/7/21/entrez PY - 2010/7/21/pubmed PY - 2010/9/4/medline SP - 211 EP - 6 JF - Ophthalmic epidemiology JO - Ophthalmic Epidemiol VL - 17 IS - 4 N2 - PURPOSE: To report the prevalence and risk factors associated with primary open-angle glaucoma (POAG) in the Kandy district of central Sri Lanka. METHODS: A cross-sectional, population-based ophthalmic survey of the inhabitants >or= 40 years of age from villages in the Kandy District, Sri Lanka was conducted. Selection was randomized using a cluster sampling process; 1721 eligible participants were identified, 1375 participated in the study and sufficient examination data to diagnose glaucoma in at least one eye was obtained in 1244 participants. A detailed ophthalmic history and examination including ocular biometry was made of each participant. Primary open-angle glaucoma was classified into three levels according to diagnostic evidence. RESULTS: The overall prevalence of POAG was 2.3% (95% CI 1.5-3.2). In the univariate analyses, increasing age (P = 0.001), intraocular pressure (IOP) (P < 0.001), myopia (P < 0.001) and axial length (P = 0.003) were significantly associated with POAG. In the multivariate analysis, age (P = 0.001), mean IOP (P < 0.001) and mean axial length (P = 0.008) were significant risk factors of POAG. CONCLUSIONS: The prevalence of POAG in the population aged >or=40 years in central Sri Lanka was 2.3%. POAG in this population was independently associated with increasing age, IOP and axial length. SN - 1744-5086 UR - https://www.unboundmedicine.com/medline/citation/20642343/Prevalence_of_and_risk_factors_for_primary_open_angle_glaucoma_in_central_Sri_Lanka:_the_Kandy_eye_study_ L2 - http://www.tandfonline.com/doi/full/10.3109/09286586.2010.483753 DB - PRIME DP - Unbound Medicine ER -