Tags

Type your tag names separated by a space and hit enter

Impact of multivessel coronary artery disease and noninfarct-related artery revascularization on outcome of patients with ST-elevation myocardial infarction transferred for primary percutaneous coronary intervention (from the EUROTRANSFER Registry).
Am J Cardiol. 2010 Aug 01; 106(3):342-7.AJ

Abstract

The aim of the study was to assess the impact of multivessel coronary artery disease (MVD) and noninfarct-related artery (non-IRA) revascularization during index percutaneous coronary intervention (PCI) on outcomes of patients with ST-segment elevation myocardial infarction (STEMI). Data on 1,598 of 1,650 patients with complete angiographic data, with >or=1 significantly stenosed epicardial coronary artery, and without previous coronary artery bypass grafting were retrieved from the EUROTRANSFER Registry database. Patients with 1-, 2-, and 3-vessel disease made up 48.5%, 32.0%, and 19.5% of the registry population, respectively. Patients with MVD were less likely to achieve final Thrombolysis In Myocardial Infarction grade 3 flow (1- vs 2- vs 3-vessel disease, 93.6% vs 89.3% vs 87.9%, respectively, p = 0.003) and ST-segment resolution >50% within 60 minutes after PCI (1- vs 2- vs 3-vessel disease, 80.9% vs 77.5% vs 69.3%, respectively, p <0.001). They were also at higher risk of death during 1-year follow-up (1- vs 2- vs 3-vessel disease, 4.9% vs 7.4% vs 13.5%, respectively, p <0.001), and MVD was identified as an independent predictor of 1-year death. In 70 patients (9%) non-IRA PCI was performed during index PCI. These patients were at higher risk of 30-day and 1-year death compared to patients without non-IRA PCI, but this difference in mortality was no longer significant after adjustment for covariates. In conclusion, patients with MVD have decreased epicardial and myocardial reperfusion success and had worse prognosis after primary PCI for STEMI compared to patients with 1-vessel disease. In this large multicenter registry, non-IRA PCI during the index procedure was performed in 9% of patients with MVD and it was associated with increased 1-year mortality.

Authors+Show Affiliations

2nd Department of Cardiology, Jagiellonian University, Medical College, Krakow, Poland.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20643243

Citation

Dziewierz, Artur, et al. "Impact of Multivessel Coronary Artery Disease and Noninfarct-related Artery Revascularization On Outcome of Patients With ST-elevation Myocardial Infarction Transferred for Primary Percutaneous Coronary Intervention (from the EUROTRANSFER Registry)." The American Journal of Cardiology, vol. 106, no. 3, 2010, pp. 342-7.
Dziewierz A, Siudak Z, Rakowski T, et al. Impact of multivessel coronary artery disease and noninfarct-related artery revascularization on outcome of patients with ST-elevation myocardial infarction transferred for primary percutaneous coronary intervention (from the EUROTRANSFER Registry). Am J Cardiol. 2010;106(3):342-7.
Dziewierz, A., Siudak, Z., Rakowski, T., Zasada, W., Dubiel, J. S., & Dudek, D. (2010). Impact of multivessel coronary artery disease and noninfarct-related artery revascularization on outcome of patients with ST-elevation myocardial infarction transferred for primary percutaneous coronary intervention (from the EUROTRANSFER Registry). The American Journal of Cardiology, 106(3), 342-7. https://doi.org/10.1016/j.amjcard.2010.03.029
Dziewierz A, et al. Impact of Multivessel Coronary Artery Disease and Noninfarct-related Artery Revascularization On Outcome of Patients With ST-elevation Myocardial Infarction Transferred for Primary Percutaneous Coronary Intervention (from the EUROTRANSFER Registry). Am J Cardiol. 2010 Aug 1;106(3):342-7. PubMed PMID: 20643243.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Impact of multivessel coronary artery disease and noninfarct-related artery revascularization on outcome of patients with ST-elevation myocardial infarction transferred for primary percutaneous coronary intervention (from the EUROTRANSFER Registry). AU - Dziewierz,Artur, AU - Siudak,Zbigniew, AU - Rakowski,Tomasz, AU - Zasada,Wojciech, AU - Dubiel,Jacek S, AU - Dudek,Dariusz, Y1 - 2010/06/18/ PY - 2010/01/25/received PY - 2010/03/22/revised PY - 2010/03/22/accepted PY - 2010/7/21/entrez PY - 2010/7/21/pubmed PY - 2010/8/13/medline SP - 342 EP - 7 JF - The American journal of cardiology JO - Am J Cardiol VL - 106 IS - 3 N2 - The aim of the study was to assess the impact of multivessel coronary artery disease (MVD) and noninfarct-related artery (non-IRA) revascularization during index percutaneous coronary intervention (PCI) on outcomes of patients with ST-segment elevation myocardial infarction (STEMI). Data on 1,598 of 1,650 patients with complete angiographic data, with >or=1 significantly stenosed epicardial coronary artery, and without previous coronary artery bypass grafting were retrieved from the EUROTRANSFER Registry database. Patients with 1-, 2-, and 3-vessel disease made up 48.5%, 32.0%, and 19.5% of the registry population, respectively. Patients with MVD were less likely to achieve final Thrombolysis In Myocardial Infarction grade 3 flow (1- vs 2- vs 3-vessel disease, 93.6% vs 89.3% vs 87.9%, respectively, p = 0.003) and ST-segment resolution >50% within 60 minutes after PCI (1- vs 2- vs 3-vessel disease, 80.9% vs 77.5% vs 69.3%, respectively, p <0.001). They were also at higher risk of death during 1-year follow-up (1- vs 2- vs 3-vessel disease, 4.9% vs 7.4% vs 13.5%, respectively, p <0.001), and MVD was identified as an independent predictor of 1-year death. In 70 patients (9%) non-IRA PCI was performed during index PCI. These patients were at higher risk of 30-day and 1-year death compared to patients without non-IRA PCI, but this difference in mortality was no longer significant after adjustment for covariates. In conclusion, patients with MVD have decreased epicardial and myocardial reperfusion success and had worse prognosis after primary PCI for STEMI compared to patients with 1-vessel disease. In this large multicenter registry, non-IRA PCI during the index procedure was performed in 9% of patients with MVD and it was associated with increased 1-year mortality. SN - 1879-1913 UR - https://www.unboundmedicine.com/medline/citation/20643243/Impact_of_multivessel_coronary_artery_disease_and_noninfarct_related_artery_revascularization_on_outcome_of_patients_with_ST_elevation_myocardial_infarction_transferred_for_primary_percutaneous_coronary_intervention__from_the_EUROTRANSFER_Registry__ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9149(10)00778-2 DB - PRIME DP - Unbound Medicine ER -