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Effects of a very-low-calorie diet on long-term glycemic control in obese type 2 diabetic subjects.
Arch Intern Med. 1991 Jul; 151(7):1334-40.AI

Abstract

We tested the hypothesis that the use of a very-low-calorie diet (VLCD) in combination with behavior modification would promote long-term glycemic control in obese type 2 diabetic subjects. Thirty-six diabetic subjects were randomly assigned to a standard behavior therapy program or to a behavior therapy program that included an 8-week period of VLCD. The behavior therapy group consumed a balanced diet of 4200 to 6300 J/d throughout the 20-week program. The VLCD group consumed a balanced diet of 4200 to 6300 J for weeks 1 to 4, followed by a VLCD (1680 J/d of lean meat, fish, and fowl) for weeks 5 to 12. The VLCD group then gradually reintroduced other foods during weeks 13 to 16 and consumed a balanced diet of 4200 to 6300 J/d for weeks 17 to 20. Thirty-three of the 36 subjects completed the 20-week program and the 1-year follow-up. Use of the VLCD produced greater decreases in fasting glucose at the end of the 20-week program and at 1-year follow-up and greater long-term reductions in HbA1. The VLCD group also had greater weight losses at week 20, but weight losses from pretreatment to 1-year follow-up were similar in the two treatment groups. The improved glycemic control with the VLCD appeared to be due to increased insulin secretion, but further research is needed to confirm this.

Authors+Show Affiliations

Wing RR
University of Pittsburgh, School of Medicine, PA.
Marcus MD
No affiliation info available
Salata R
No affiliation info available
Epstein LH
No affiliation info available
Miaskiewicz S
No affiliation info available
Blair EH
No affiliation info available

MeSH

AdultAgedBlood GlucoseDiabetes Mellitus, Type 2Diet, ReducingElectrocardiographyEnergy IntakeExerciseFemaleFollow-Up StudiesHemoglobin AHumansInsulinLipidsMaleMiddle AgedMonitoring, PhysiologicObesityPatient ComplianceWeight Loss

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

2064484

Citation

Wing, R R., et al. "Effects of a Very-low-calorie Diet On Long-term Glycemic Control in Obese Type 2 Diabetic Subjects." Archives of Internal Medicine, vol. 151, no. 7, 1991, pp. 1334-40.
Wing RR, Marcus MD, Salata R, et al. Effects of a very-low-calorie diet on long-term glycemic control in obese type 2 diabetic subjects. Arch Intern Med. 1991;151(7):1334-40.
Wing, R. R., Marcus, M. D., Salata, R., Epstein, L. H., Miaskiewicz, S., & Blair, E. H. (1991). Effects of a very-low-calorie diet on long-term glycemic control in obese type 2 diabetic subjects. Archives of Internal Medicine, 151(7), 1334-40.
Wing RR, et al. Effects of a Very-low-calorie Diet On Long-term Glycemic Control in Obese Type 2 Diabetic Subjects. Arch Intern Med. 1991;151(7):1334-40. PubMed PMID: 2064484.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of a very-low-calorie diet on long-term glycemic control in obese type 2 diabetic subjects. AU - Wing,R R, AU - Marcus,M D, AU - Salata,R, AU - Epstein,L H, AU - Miaskiewicz,S, AU - Blair,E H, PY - 1991/7/1/pubmed PY - 1991/7/1/medline PY - 1991/7/1/entrez SP - 1334 EP - 40 JF - Archives of internal medicine JO - Arch Intern Med VL - 151 IS - 7 N2 - We tested the hypothesis that the use of a very-low-calorie diet (VLCD) in combination with behavior modification would promote long-term glycemic control in obese type 2 diabetic subjects. Thirty-six diabetic subjects were randomly assigned to a standard behavior therapy program or to a behavior therapy program that included an 8-week period of VLCD. The behavior therapy group consumed a balanced diet of 4200 to 6300 J/d throughout the 20-week program. The VLCD group consumed a balanced diet of 4200 to 6300 J for weeks 1 to 4, followed by a VLCD (1680 J/d of lean meat, fish, and fowl) for weeks 5 to 12. The VLCD group then gradually reintroduced other foods during weeks 13 to 16 and consumed a balanced diet of 4200 to 6300 J/d for weeks 17 to 20. Thirty-three of the 36 subjects completed the 20-week program and the 1-year follow-up. Use of the VLCD produced greater decreases in fasting glucose at the end of the 20-week program and at 1-year follow-up and greater long-term reductions in HbA1. The VLCD group also had greater weight losses at week 20, but weight losses from pretreatment to 1-year follow-up were similar in the two treatment groups. The improved glycemic control with the VLCD appeared to be due to increased insulin secretion, but further research is needed to confirm this. SN - 0003-9926 UR - https://www.unboundmedicine.com/medline/citation/2064484/Effects_of_a_very_low_calorie_diet_on_long_term_glycemic_control_in_obese_type_2_diabetic_subjects_ DB - PRIME DP - Unbound Medicine ER -