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Antifungal activity of essential oil from fruits of Indian Cuminum cyminum.
Pharm Biol. 2010 Jul; 48(7):834-8.PB

Abstract

The essential oil of fruits of Cuminum cyminum L. (Apiaceae), from India, was analyzed by GC and GC-MS, and its antifungal activity was tested on dermatophytes and phytopathogens, fungi, yeasts and some new Aspergilli. The most abundant components were cumin aldehyde, pinenes, and p-cymene, and a fraction of oxygenate compounds such as alcohol and epoxides. Because of the large amount of the highly volatile components in the cumin extract, we used a modified recent technique to evaluate the antifungal activity only of the volatile parts at doses from 5 to 20 microL of pure essential oil. Antifungal testing showed that Cuminum cyminum is active in general on all fungi but in particular on the dermatophytes, where Trichophyton rubrum was the most inhibited fungus also at the lowest dose of 5 microL. Less sensitive to treatment were the phytopathogens.

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Authors+Show Affiliations

Romagnoli C
Department of Paleobiology and Botanical Garden, University of Modena e Reggio Emilia, 41100 Modena, Italy. carlo.romagnoli@unimore.it
Andreotti E
No affiliation info available
Maietti S
No affiliation info available
Mahendra R
No affiliation info available
Mares D
No affiliation info available

MeSH

Antifungal AgentsArthrodermataceaeCuminumFungiMedicine, AyurvedicMicrobial Sensitivity TestsOils, VolatileTrichophytonYeasts

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20645785

Citation

Romagnoli, Carlo, et al. "Antifungal Activity of Essential Oil From Fruits of Indian Cuminum Cyminum." Pharmaceutical Biology, vol. 48, no. 7, 2010, pp. 834-8.
Romagnoli C, Andreotti E, Maietti S, et al. Antifungal activity of essential oil from fruits of Indian Cuminum cyminum. Pharm Biol. 2010;48(7):834-8.
Romagnoli, C., Andreotti, E., Maietti, S., Mahendra, R., & Mares, D. (2010). Antifungal activity of essential oil from fruits of Indian Cuminum cyminum. Pharmaceutical Biology, 48(7), 834-8. https://doi.org/10.3109/13880200903283715
Romagnoli C, et al. Antifungal Activity of Essential Oil From Fruits of Indian Cuminum Cyminum. Pharm Biol. 2010;48(7):834-8. PubMed PMID: 20645785.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antifungal activity of essential oil from fruits of Indian Cuminum cyminum. AU - Romagnoli,Carlo, AU - Andreotti,Elisa, AU - Maietti,Silvia, AU - Mahendra,Rai, AU - Mares,Donatella, PY - 2010/7/22/entrez PY - 2010/7/22/pubmed PY - 2010/12/14/medline SP - 834 EP - 8 JF - Pharmaceutical biology JO - Pharm Biol VL - 48 IS - 7 N2 - The essential oil of fruits of Cuminum cyminum L. (Apiaceae), from India, was analyzed by GC and GC-MS, and its antifungal activity was tested on dermatophytes and phytopathogens, fungi, yeasts and some new Aspergilli. The most abundant components were cumin aldehyde, pinenes, and p-cymene, and a fraction of oxygenate compounds such as alcohol and epoxides. Because of the large amount of the highly volatile components in the cumin extract, we used a modified recent technique to evaluate the antifungal activity only of the volatile parts at doses from 5 to 20 microL of pure essential oil. Antifungal testing showed that Cuminum cyminum is active in general on all fungi but in particular on the dermatophytes, where Trichophyton rubrum was the most inhibited fungus also at the lowest dose of 5 microL. Less sensitive to treatment were the phytopathogens. SN - 1744-5116 UR - https://www.unboundmedicine.com/medline/citation/20645785/Antifungal_activity_of_essential_oil_from_fruits_of_Indian_Cuminum_cyminum_ L2 - https://www.tandfonline.com/doi/full/10.3109/13880200903283715 DB - PRIME DP - Unbound Medicine ER -