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Antibacterial properties of essential oils and methanol extracts of sweet basil Ocimum basilicum occurring in Bangladesh.
Pharm Biol. 2010 May; 48(5):504-11.PB

Abstract

The antibacterial potential of essential oils and methanol extracts of sweet basil Ocimum basilicum L. (Lamiaceae) was evaluated for controlling the growth range of food-borne pathogenic bacteria. Essential oils extracted by hydrodistillation from the leaves and stems were analyzed by GC-MS. Fifty-seven compounds representing 94.9 and 96.1% of the total leaf and stem oils, respectively, were identified, of which methyl chavicol (36.7 and 29.9%), gitoxigenin (9.3 and 10.2%), trimethoquinol (10.3 and 8.4%), beta-guaiene (3.7 and 4.1%), aciphyllene (3.4 and 3.0%), alizarin (3.2 and 4.4%), naphthaline (2.2 and 3.8%), (-)-caryophyllene (2.0 and 1.9%), and mequinol (1.6 and 1.8%) were the major compounds. The essential oils (10 microL/disc of 1:5, v/v dilution with methanol) and methanol extracts (300 microg/disc) of O. basilicum displayed a great potential of antibacterial activity against Bacillius cereus, B. subtilis, B. megaterium, Staphylococcus aureus, Listeria monocytogenes, Escherichia coli, Shigella boydii, S. dysenteriae, Vibrio parahaemolyticus, V. mimicus, and Salmonella typhi with their respective zones of inhibition of 11.2-21.1 mm and MIC values of 62.5-500 microg/mL. The results of this study suggest that the natural products derived from O. basilicum may have potential use in the food and/or pharmaceutical industries as antimicrobial agents.

Authors+Show Affiliations

Chemistry Division, Atomic Energy Centre, Ramna, Dhaka, Bangladesh.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

20645791

Citation

Hossain, M Amzad, et al. "Antibacterial Properties of Essential Oils and Methanol Extracts of Sweet Basil Ocimum Basilicum Occurring in Bangladesh." Pharmaceutical Biology, vol. 48, no. 5, 2010, pp. 504-11.
Hossain MA, Kabir MJ, Salehuddin SM, et al. Antibacterial properties of essential oils and methanol extracts of sweet basil Ocimum basilicum occurring in Bangladesh. Pharm Biol. 2010;48(5):504-11.
Hossain, M. A., Kabir, M. J., Salehuddin, S. M., Rahman, S. M., Das, A. K., Singha, S. K., Alam, M. K., & Rahman, A. (2010). Antibacterial properties of essential oils and methanol extracts of sweet basil Ocimum basilicum occurring in Bangladesh. Pharmaceutical Biology, 48(5), 504-11. https://doi.org/10.3109/13880200903190977
Hossain MA, et al. Antibacterial Properties of Essential Oils and Methanol Extracts of Sweet Basil Ocimum Basilicum Occurring in Bangladesh. Pharm Biol. 2010;48(5):504-11. PubMed PMID: 20645791.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antibacterial properties of essential oils and methanol extracts of sweet basil Ocimum basilicum occurring in Bangladesh. AU - Hossain,M Amzad, AU - Kabir,M J, AU - Salehuddin,S M, AU - Rahman,S M Mizanur, AU - Das,A K, AU - Singha,Sandip Kumar, AU - Alam,Md Khorshed, AU - Rahman,Atiqur, PY - 2010/7/22/entrez PY - 2010/7/22/pubmed PY - 2011/4/26/medline SP - 504 EP - 11 JF - Pharmaceutical biology JO - Pharm Biol VL - 48 IS - 5 N2 - The antibacterial potential of essential oils and methanol extracts of sweet basil Ocimum basilicum L. (Lamiaceae) was evaluated for controlling the growth range of food-borne pathogenic bacteria. Essential oils extracted by hydrodistillation from the leaves and stems were analyzed by GC-MS. Fifty-seven compounds representing 94.9 and 96.1% of the total leaf and stem oils, respectively, were identified, of which methyl chavicol (36.7 and 29.9%), gitoxigenin (9.3 and 10.2%), trimethoquinol (10.3 and 8.4%), beta-guaiene (3.7 and 4.1%), aciphyllene (3.4 and 3.0%), alizarin (3.2 and 4.4%), naphthaline (2.2 and 3.8%), (-)-caryophyllene (2.0 and 1.9%), and mequinol (1.6 and 1.8%) were the major compounds. The essential oils (10 microL/disc of 1:5, v/v dilution with methanol) and methanol extracts (300 microg/disc) of O. basilicum displayed a great potential of antibacterial activity against Bacillius cereus, B. subtilis, B. megaterium, Staphylococcus aureus, Listeria monocytogenes, Escherichia coli, Shigella boydii, S. dysenteriae, Vibrio parahaemolyticus, V. mimicus, and Salmonella typhi with their respective zones of inhibition of 11.2-21.1 mm and MIC values of 62.5-500 microg/mL. The results of this study suggest that the natural products derived from O. basilicum may have potential use in the food and/or pharmaceutical industries as antimicrobial agents. SN - 1744-5116 UR - https://www.unboundmedicine.com/medline/citation/20645791/Antibacterial_properties_of_essential_oils_and_methanol_extracts_of_sweet_basil_Ocimum_basilicum_occurring_in_Bangladesh_ DB - PRIME DP - Unbound Medicine ER -