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Antioxidant potential and radical scavenging effects of various extracts from Abutilon indicum and Abutilon muticum.
Pharm Biol. 2010 Mar; 48(3):282-9.PB

Abstract

Abutilon indicum L. (Malvaceae) and Abutilon muticum DC. (Malvaceae) are traditional medicinal herbs used for analgesic, anthelmintic, hepatoprotective, and hypoglycemic properties. These effects may be correlated with the presence of antioxidant compounds. Extracts in organic solvents from the aerial parts and roots of both species were prepared and evaluated for their total antioxidant capacity (TAC), total phenolic content, and total flavonoid content. The Trolox equivalent antioxidant capacity (TEAC) of all the extracts of both plants was found, employing ABTS and FRAP assays. TEAC values ranged from 3.019 to 10.5 muM for n-hexane and butanol fractions of Abutilon indicum and from 2.247 to 14.208 muM for n-hexane and butanol fractions of Abutilon muticum, respectively, using the ABTS assay. The FRAP assay showed reducing powers of the fractions in the order of butanol > ethyl acetate > chloroform > n-hexane and butanol > chloroform > hexane > ethyl acetate for Abutilon indicum and Abutilon muticum, respectively. EC(50) and T(EC50) values for the extracts of both plants were determined using the DPPH free radical assay. The reaction kinetics with this free radical indicated the presence of both slow reacting and fast reacting antioxidant components in the extracts of both plants. The antioxidant/radical scavenging capacity of the extracts was found to be a dose-dependent activity. The results obtained in the present study indicate that both Abutilon species are potential sources of natural antioxidants.

Authors+Show Affiliations

Center for Natural Product Research, Department of Chemistry, GC University, Lahore, Pakistan. sammiayasmin@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20645814

Citation

Yasmin, Sammia, et al. "Antioxidant Potential and Radical Scavenging Effects of Various Extracts From Abutilon Indicum and Abutilon Muticum." Pharmaceutical Biology, vol. 48, no. 3, 2010, pp. 282-9.
Yasmin S, Kashmiri MA, Asghar MN, et al. Antioxidant potential and radical scavenging effects of various extracts from Abutilon indicum and Abutilon muticum. Pharm Biol. 2010;48(3):282-9.
Yasmin, S., Kashmiri, M. A., Asghar, M. N., Ahmad, M., & Mohy-ud-Din, A. (2010). Antioxidant potential and radical scavenging effects of various extracts from Abutilon indicum and Abutilon muticum. Pharmaceutical Biology, 48(3), 282-9. https://doi.org/10.3109/13880200903110769
Yasmin S, et al. Antioxidant Potential and Radical Scavenging Effects of Various Extracts From Abutilon Indicum and Abutilon Muticum. Pharm Biol. 2010;48(3):282-9. PubMed PMID: 20645814.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antioxidant potential and radical scavenging effects of various extracts from Abutilon indicum and Abutilon muticum. AU - Yasmin,Sammia, AU - Kashmiri,Muhammad Akram, AU - Asghar,Muhammad Nadeem, AU - Ahmad,Mushtaq, AU - Mohy-ud-Din,Ayesha, PY - 2010/7/22/entrez PY - 2010/7/22/pubmed PY - 2010/12/14/medline SP - 282 EP - 9 JF - Pharmaceutical biology JO - Pharm Biol VL - 48 IS - 3 N2 - Abutilon indicum L. (Malvaceae) and Abutilon muticum DC. (Malvaceae) are traditional medicinal herbs used for analgesic, anthelmintic, hepatoprotective, and hypoglycemic properties. These effects may be correlated with the presence of antioxidant compounds. Extracts in organic solvents from the aerial parts and roots of both species were prepared and evaluated for their total antioxidant capacity (TAC), total phenolic content, and total flavonoid content. The Trolox equivalent antioxidant capacity (TEAC) of all the extracts of both plants was found, employing ABTS and FRAP assays. TEAC values ranged from 3.019 to 10.5 muM for n-hexane and butanol fractions of Abutilon indicum and from 2.247 to 14.208 muM for n-hexane and butanol fractions of Abutilon muticum, respectively, using the ABTS assay. The FRAP assay showed reducing powers of the fractions in the order of butanol > ethyl acetate > chloroform > n-hexane and butanol > chloroform > hexane > ethyl acetate for Abutilon indicum and Abutilon muticum, respectively. EC(50) and T(EC50) values for the extracts of both plants were determined using the DPPH free radical assay. The reaction kinetics with this free radical indicated the presence of both slow reacting and fast reacting antioxidant components in the extracts of both plants. The antioxidant/radical scavenging capacity of the extracts was found to be a dose-dependent activity. The results obtained in the present study indicate that both Abutilon species are potential sources of natural antioxidants. SN - 1744-5116 UR - https://www.unboundmedicine.com/medline/citation/20645814/Antioxidant_potential_and_radical_scavenging_effects_of_various_extracts_from_Abutilon_indicum_and_Abutilon_muticum_ L2 - https://www.tandfonline.com/doi/full/10.3109/13880200903110769 DB - PRIME DP - Unbound Medicine ER -