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Outbreak of scrub typhus in Pondicherry.
J Assoc Physicians India 2010; 58:24-8JA

Abstract

AIM

To describe the diverse clinical and laboratory manifestations of scrub typhus diagnosed in Pondicherry Institute of Medical Sciences, Pondicherry.

MATERIALS AND METHODS

All cases of febrile illness diagnosed as scrub typhus over a period of 2 years were analysed. Diagnosis was based on the presence of the eschar and/or positive Weil Felix test with a titre of > 1:80.

RESULTS

Fifty cases of scrub typhus were seen over a period of 2 years (April 2006 and April 2008). Common symptoms were high grade fever of 7-14 days duration, nausea, vomiting, headache, myalgia, cough and breathlessness. Eschar was seen in 23 cases (46%) and the common sites were axilla, breast and groin. Weil Felix test was positive in 39 cases (78%). Liver enzymes were elevated in nearly all cases (95.9%). Multiple Organ Dysfunction Syndrome (MODS) was present in one third of our patients (17 out of 50, 34%). Hypotension (8 patients, 16%), renal impairment (6 patients, 12%), ARDS (4 patients, 8%) and meningitis (7 patients, 14%) were some of the important complications. There was a dramatic response to doxycycline in nearly all the patients.

CONCLUSION

Scrub typhus has emerged as an important cause of febrile illness in Pondicherry. Empirical treatment with doxycycline is justified in endemic areas.

Authors+Show Affiliations

Department of Medicine & Microbiology, Pondicherry Institute of Medical Sciences, Kalapet, Pondicherry - 605 014.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20649095

Citation

Vivekanandan, M, et al. "Outbreak of Scrub Typhus in Pondicherry." The Journal of the Association of Physicians of India, vol. 58, 2010, pp. 24-8.
Vivekanandan M, Mani A, Priya YS, et al. Outbreak of scrub typhus in Pondicherry. J Assoc Physicians India. 2010;58:24-8.
Vivekanandan, M., Mani, A., Priya, Y. S., Singh, A. P., Jayakumar, S., & Purty, S. (2010). Outbreak of scrub typhus in Pondicherry. The Journal of the Association of Physicians of India, 58, pp. 24-8.
Vivekanandan M, et al. Outbreak of Scrub Typhus in Pondicherry. J Assoc Physicians India. 2010;58:24-8. PubMed PMID: 20649095.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Outbreak of scrub typhus in Pondicherry. AU - Vivekanandan,M, AU - Mani,Anna, AU - Priya,Yamini Sundara, AU - Singh,Ajai Pratap, AU - Jayakumar,Samuel, AU - Purty,Shashikala, PY - 2010/7/24/entrez PY - 2010/7/24/pubmed PY - 2010/8/6/medline SP - 24 EP - 8 JF - The Journal of the Association of Physicians of India JO - J Assoc Physicians India VL - 58 N2 - AIM: To describe the diverse clinical and laboratory manifestations of scrub typhus diagnosed in Pondicherry Institute of Medical Sciences, Pondicherry. MATERIALS AND METHODS: All cases of febrile illness diagnosed as scrub typhus over a period of 2 years were analysed. Diagnosis was based on the presence of the eschar and/or positive Weil Felix test with a titre of > 1:80. RESULTS: Fifty cases of scrub typhus were seen over a period of 2 years (April 2006 and April 2008). Common symptoms were high grade fever of 7-14 days duration, nausea, vomiting, headache, myalgia, cough and breathlessness. Eschar was seen in 23 cases (46%) and the common sites were axilla, breast and groin. Weil Felix test was positive in 39 cases (78%). Liver enzymes were elevated in nearly all cases (95.9%). Multiple Organ Dysfunction Syndrome (MODS) was present in one third of our patients (17 out of 50, 34%). Hypotension (8 patients, 16%), renal impairment (6 patients, 12%), ARDS (4 patients, 8%) and meningitis (7 patients, 14%) were some of the important complications. There was a dramatic response to doxycycline in nearly all the patients. CONCLUSION: Scrub typhus has emerged as an important cause of febrile illness in Pondicherry. Empirical treatment with doxycycline is justified in endemic areas. SN - 0004-5772 UR - https://www.unboundmedicine.com/medline/citation/20649095/Outbreak_of_scrub_typhus_in_Pondicherry_ L2 - http://www.diseaseinfosearch.org/result/7277 DB - PRIME DP - Unbound Medicine ER -