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Performance evaluation of the DrugWipe® 5/5+ on-site oral fluid screening device.
Int J Legal Med. 2011 Sep; 125(5):675-83.IJ

Abstract

This study presents a retrospective performance evaluation of an on-site oral fluid drug screening device DrugWipe® 5/5+ (Securetec). The results obtained by the device were compared with gas chromatography-mass spectrometry confirmation analysis results in whole blood. Data used in the comparison were based on 1,807 real cases in which the Finnish police had conducted an on-site drug test on persons suspected of driving under the influence of drugs. The present data cover only cases wherein the DrugWipe device has shown a positive result for at least one substance. The data were compiled from the databases of Alcohol and Drug Analytics Unit at the National Institute for Health and Welfare. The performance of the DrugWipe was evaluated for its relevant drug groups: amphetamines, cannabis, opiates, and cocaine. The evaluation was carried out by calculating the sensitivity, specificity, and accuracy as well as the positive and negative predictive values. These calculations were based on the classification of the results as true positives, false positives, true negatives, and false negatives. Additionally, the demographics of the cases and analytical findings in whole blood are discussed. According to this study, the DrugWipe device performed quite well in detecting amphetamines, the most frequently encountered group of illicit drugs in Finnish traffic. The performance of the cannabis, opiate, and cocaine tests was not at the same level.

Authors+Show Affiliations

Alcohol and Drug Analytics Unit, National Institute for Health and Welfare, Helsinki, Finland.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20652713

Citation

Pehrsson, Anna, et al. "Performance Evaluation of the DrugWipe® 5/5+ On-site Oral Fluid Screening Device." International Journal of Legal Medicine, vol. 125, no. 5, 2011, pp. 675-83.
Pehrsson A, Blencowe T, Vimpari K, et al. Performance evaluation of the DrugWipe® 5/5+ on-site oral fluid screening device. Int J Legal Med. 2011;125(5):675-83.
Pehrsson, A., Blencowe, T., Vimpari, K., Impinen, A., Gunnar, T., & Lillsunde, P. (2011). Performance evaluation of the DrugWipe® 5/5+ on-site oral fluid screening device. International Journal of Legal Medicine, 125(5), 675-83. https://doi.org/10.1007/s00414-010-0493-x
Pehrsson A, et al. Performance Evaluation of the DrugWipe® 5/5+ On-site Oral Fluid Screening Device. Int J Legal Med. 2011;125(5):675-83. PubMed PMID: 20652713.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Performance evaluation of the DrugWipe® 5/5+ on-site oral fluid screening device. AU - Pehrsson,Anna, AU - Blencowe,Tom, AU - Vimpari,Kari, AU - Impinen,Antti, AU - Gunnar,Teemu, AU - Lillsunde,Pirjo, Y1 - 2010/07/23/ PY - 2010/04/08/received PY - 2010/07/06/accepted PY - 2010/7/24/entrez PY - 2010/7/24/pubmed PY - 2011/12/24/medline SP - 675 EP - 83 JF - International journal of legal medicine JO - Int J Legal Med VL - 125 IS - 5 N2 - This study presents a retrospective performance evaluation of an on-site oral fluid drug screening device DrugWipe® 5/5+ (Securetec). The results obtained by the device were compared with gas chromatography-mass spectrometry confirmation analysis results in whole blood. Data used in the comparison were based on 1,807 real cases in which the Finnish police had conducted an on-site drug test on persons suspected of driving under the influence of drugs. The present data cover only cases wherein the DrugWipe device has shown a positive result for at least one substance. The data were compiled from the databases of Alcohol and Drug Analytics Unit at the National Institute for Health and Welfare. The performance of the DrugWipe was evaluated for its relevant drug groups: amphetamines, cannabis, opiates, and cocaine. The evaluation was carried out by calculating the sensitivity, specificity, and accuracy as well as the positive and negative predictive values. These calculations were based on the classification of the results as true positives, false positives, true negatives, and false negatives. Additionally, the demographics of the cases and analytical findings in whole blood are discussed. According to this study, the DrugWipe device performed quite well in detecting amphetamines, the most frequently encountered group of illicit drugs in Finnish traffic. The performance of the cannabis, opiate, and cocaine tests was not at the same level. SN - 1437-1596 UR - https://www.unboundmedicine.com/medline/citation/20652713/Performance_evaluation_of_the_DrugWipe®_5/5+_on_site_oral_fluid_screening_device_ L2 - https://dx.doi.org/10.1007/s00414-010-0493-x DB - PRIME DP - Unbound Medicine ER -