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Controversies in the treatment of chronic rhinosinusitis.
Expert Rev Respir Med. 2010 Aug; 4(4):463-77.ER

Abstract

Chronic rhinosinusitis (CRS) including nasal polyps is a chronic inflammatory disease involving the mucosa of the nose and one or more paranasal sinuses. Despite differing hypotheses, the cause remains poorly understood. The key issue is the maintaining of ostial patency. CRS with nasal polyps is considered to be a subgroup of CRS. Major symptoms are nasal congestion or blockage, loss of smell, rhinorrhea, post-nasal drip, and facial pain or pressure. CRS is associated with lower airway disease such asthma, chronic obstructive pulmonary disease and bronchiectasis. In CRS with and without nasal polyps, medical treatment, including nasal and oral corticosteroids, is the first therapeutic option. The treatment of CRS still remains an unmet need. Corticosteroids are the mainstay of treatment and are the most effective drugs for treating airway inflammatory diseases such as asthma, allergic rhinitis and CRS. Endoscopic sinus surgery is only recommended when medical treatment fails. After surgery, medical treatment, including nasal and oral corticosteroids, is recommended.

Authors+Show Affiliations

Rhinology Unit and Smell Clinic, Department of Otorhinolaryngology-Head & Neck Surgery, Hospital Clínic i Universitari de Barcelona, c/ Villarroel, 170, Barcelona 08036, Catalonia, Spain. guilemany@gmail.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

20658908

Citation

Guilemany, José Maria, et al. "Controversies in the Treatment of Chronic Rhinosinusitis." Expert Review of Respiratory Medicine, vol. 4, no. 4, 2010, pp. 463-77.
Guilemany JM, Alobid I, Mullol J. Controversies in the treatment of chronic rhinosinusitis. Expert Rev Respir Med. 2010;4(4):463-77.
Guilemany, J. M., Alobid, I., & Mullol, J. (2010). Controversies in the treatment of chronic rhinosinusitis. Expert Review of Respiratory Medicine, 4(4), 463-77. https://doi.org/10.1586/ers.10.49
Guilemany JM, Alobid I, Mullol J. Controversies in the Treatment of Chronic Rhinosinusitis. Expert Rev Respir Med. 2010;4(4):463-77. PubMed PMID: 20658908.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Controversies in the treatment of chronic rhinosinusitis. AU - Guilemany,José Maria, AU - Alobid,Isam, AU - Mullol,Joaquim, PY - 2010/7/28/entrez PY - 2010/7/28/pubmed PY - 2010/11/16/medline SP - 463 EP - 77 JF - Expert review of respiratory medicine JO - Expert Rev Respir Med VL - 4 IS - 4 N2 - Chronic rhinosinusitis (CRS) including nasal polyps is a chronic inflammatory disease involving the mucosa of the nose and one or more paranasal sinuses. Despite differing hypotheses, the cause remains poorly understood. The key issue is the maintaining of ostial patency. CRS with nasal polyps is considered to be a subgroup of CRS. Major symptoms are nasal congestion or blockage, loss of smell, rhinorrhea, post-nasal drip, and facial pain or pressure. CRS is associated with lower airway disease such asthma, chronic obstructive pulmonary disease and bronchiectasis. In CRS with and without nasal polyps, medical treatment, including nasal and oral corticosteroids, is the first therapeutic option. The treatment of CRS still remains an unmet need. Corticosteroids are the mainstay of treatment and are the most effective drugs for treating airway inflammatory diseases such as asthma, allergic rhinitis and CRS. Endoscopic sinus surgery is only recommended when medical treatment fails. After surgery, medical treatment, including nasal and oral corticosteroids, is recommended. SN - 1747-6356 UR - https://www.unboundmedicine.com/medline/citation/20658908/Controversies_in_the_treatment_of_chronic_rhinosinusitis_ L2 - http://www.tandfonline.com/doi/full/10.1586/ers.10.49 DB - PRIME DP - Unbound Medicine ER -