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Combined effects of muscular dystrophy, ecological stress, and selenium on blood antioxidant status in broiler chickens.
Biol Trace Elem Res. 2011 Sep; 142(3):532-45.BT

Abstract

The results obtained in this study demonstrated that experimentally induced alimentary muscular dystrophy (MD) in Cobb 500 broiler chickens resulted in increased plasma concentrations of malondialdehyde (MDA), deviations in activities of erythrocyte antioxidant enzymes Cu,Zn-SOD (decrease), and CAT (increase) as well as reduction in plasma concentrations of trace elements Cu, Zn, and Se in affected birds. These data evidenced the presence of oxidative stress in birds with MD, reared both under conditions of ecological comfort and ecological stress. The increased MDA and САТ levels and the reduced Cu,Zn-SOD, Cu, Zn, and Se concentrations in healthy chickens reared under unfavorable microclimatic conditions such as higher air temperature and humidity, higher ammonia concentrations, and lower light intensity were indicative about an induced ecological stress. After the 10-day oral treatment with a selenium-containing preparation, the levels of MDA, Cu,Zn-SOD, CAT, Cu, Zn, and Se attained their normal values in chickens with MD, reared under ecologically comfortable conditions. According to our results, ecological stress was shown to exert independently a significant adverse effect upon the levels of the studied parameters and possibly to be a cause for their slower and not complete normalization despite the selenium therapy in experimental broiler chickens.

Authors+Show Affiliations

Department of Pharmacology, Physiology of Animals and Physiologic Chemistry, Faculty of Veterinary Medicine, Trakia University, Student's Campus, 6000 Stara Zagora, Bulgaria. nvgeorgieva@vmf.uni-sz.bgNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20668960

Citation

Georgieva, Nedyalka V., et al. "Combined Effects of Muscular Dystrophy, Ecological Stress, and Selenium On Blood Antioxidant Status in Broiler Chickens." Biological Trace Element Research, vol. 142, no. 3, 2011, pp. 532-45.
Georgieva NV, Stoyanchev K, Bozakova N, et al. Combined effects of muscular dystrophy, ecological stress, and selenium on blood antioxidant status in broiler chickens. Biol Trace Elem Res. 2011;142(3):532-45.
Georgieva, N. V., Stoyanchev, K., Bozakova, N., & Jotova, I. (2011). Combined effects of muscular dystrophy, ecological stress, and selenium on blood antioxidant status in broiler chickens. Biological Trace Element Research, 142(3), 532-45. https://doi.org/10.1007/s12011-010-8782-2
Georgieva NV, et al. Combined Effects of Muscular Dystrophy, Ecological Stress, and Selenium On Blood Antioxidant Status in Broiler Chickens. Biol Trace Elem Res. 2011;142(3):532-45. PubMed PMID: 20668960.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Combined effects of muscular dystrophy, ecological stress, and selenium on blood antioxidant status in broiler chickens. AU - Georgieva,Nedyalka V, AU - Stoyanchev,Krasimir, AU - Bozakova,Nadia, AU - Jotova,Ivanka, Y1 - 2010/07/29/ PY - 2010/04/20/received PY - 2010/07/15/accepted PY - 2010/7/30/entrez PY - 2010/7/30/pubmed PY - 2012/1/24/medline SP - 532 EP - 45 JF - Biological trace element research JO - Biol Trace Elem Res VL - 142 IS - 3 N2 - The results obtained in this study demonstrated that experimentally induced alimentary muscular dystrophy (MD) in Cobb 500 broiler chickens resulted in increased plasma concentrations of malondialdehyde (MDA), deviations in activities of erythrocyte antioxidant enzymes Cu,Zn-SOD (decrease), and CAT (increase) as well as reduction in plasma concentrations of trace elements Cu, Zn, and Se in affected birds. These data evidenced the presence of oxidative stress in birds with MD, reared both under conditions of ecological comfort and ecological stress. The increased MDA and САТ levels and the reduced Cu,Zn-SOD, Cu, Zn, and Se concentrations in healthy chickens reared under unfavorable microclimatic conditions such as higher air temperature and humidity, higher ammonia concentrations, and lower light intensity were indicative about an induced ecological stress. After the 10-day oral treatment with a selenium-containing preparation, the levels of MDA, Cu,Zn-SOD, CAT, Cu, Zn, and Se attained their normal values in chickens with MD, reared under ecologically comfortable conditions. According to our results, ecological stress was shown to exert independently a significant adverse effect upon the levels of the studied parameters and possibly to be a cause for their slower and not complete normalization despite the selenium therapy in experimental broiler chickens. SN - 1559-0720 UR - https://www.unboundmedicine.com/medline/citation/20668960/Combined_effects_of_muscular_dystrophy_ecological_stress_and_selenium_on_blood_antioxidant_status_in_broiler_chickens_ DB - PRIME DP - Unbound Medicine ER -