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Efficient assembly of 1-methylene-1H-indenes via palladium-catalyzed tandem reaction of 1-(2,2-dibromovinyl)-2-alkenylbenzene with arylboronic acid.
J Comb Chem. 2010 Sep 13; 12(5):670-5.JC

Abstract

Highly efficient palladium-catalyzed reaction of 1-(2,2-dibromovinyl)-2-alkenylbenzene with arylboronic acid is disclosed, which generates the functionalized 1-methylene-1H-indenes in good yields. Tandem Suzuki-Miyaura coupling and Heck reactions are involved in this process.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Ye S
Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China.
Ren H
No affiliation info available
Wu J
No affiliation info available

MeSH

AcetatesBoronic AcidsCatalysisCinnamatesCombinatorial Chemistry TechniquesCyclizationIndenesMolecular StructureOrganometallic CompoundsStereoisomerismVinyl Compounds

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20681516

Citation

Ye, Shengqing, et al. "Efficient Assembly of 1-methylene-1H-indenes Via Palladium-catalyzed Tandem Reaction of 1-(2,2-dibromovinyl)-2-alkenylbenzene With Arylboronic Acid." Journal of Combinatorial Chemistry, vol. 12, no. 5, 2010, pp. 670-5.
Ye S, Ren H, Wu J. Efficient assembly of 1-methylene-1H-indenes via palladium-catalyzed tandem reaction of 1-(2,2-dibromovinyl)-2-alkenylbenzene with arylboronic acid. J Comb Chem. 2010;12(5):670-5.
Ye, S., Ren, H., & Wu, J. (2010). Efficient assembly of 1-methylene-1H-indenes via palladium-catalyzed tandem reaction of 1-(2,2-dibromovinyl)-2-alkenylbenzene with arylboronic acid. Journal of Combinatorial Chemistry, 12(5), 670-5. https://doi.org/10.1021/cc1000693
Ye S, Ren H, Wu J. Efficient Assembly of 1-methylene-1H-indenes Via Palladium-catalyzed Tandem Reaction of 1-(2,2-dibromovinyl)-2-alkenylbenzene With Arylboronic Acid. J Comb Chem. 2010 Sep 13;12(5):670-5. PubMed PMID: 20681516.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Efficient assembly of 1-methylene-1H-indenes via palladium-catalyzed tandem reaction of 1-(2,2-dibromovinyl)-2-alkenylbenzene with arylboronic acid. AU - Ye,Shengqing, AU - Ren,Hui, AU - Wu,Jie, PY - 2010/8/5/entrez PY - 2010/8/5/pubmed PY - 2010/12/25/medline SP - 670 EP - 5 JF - Journal of combinatorial chemistry JO - J Comb Chem VL - 12 IS - 5 N2 - Highly efficient palladium-catalyzed reaction of 1-(2,2-dibromovinyl)-2-alkenylbenzene with arylboronic acid is disclosed, which generates the functionalized 1-methylene-1H-indenes in good yields. Tandem Suzuki-Miyaura coupling and Heck reactions are involved in this process. SN - 1520-4774 UR - https://www.unboundmedicine.com/medline/citation/20681516/Efficient_assembly_of_1_methylene_1H_indenes_via_palladium_catalyzed_tandem_reaction_of_1__22_dibromovinyl__2_alkenylbenzene_with_arylboronic_acid_ L2 - https://doi.org/10.1021/cc1000693 DB - PRIME DP - Unbound Medicine ER -