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[Contact eczema and epicutaneous tests--distribution of allergens and changes in the spectrum in Vienna].
Wien Klin Wochenschr. 1991; 103(9):263-7.WK

Abstract

Thousands of contact antigens have been defined. It is, however, remarkable that only a small group of substances (15 to 20) have proved to be frequent or otherwise important causes of allergic contact dermatitis. In agreement with reports from comparable centres, metals are high up on the "hitlist" of frequent allergens (nickel 24%, cobalt 9%, chromates 6%), followed by ingredients of cosmetics and toiletries (fragrances 16%, balsam of Peru 10%, Kathon 5%), whilst already way back are topical medicines (neomycin 4%, parabens 3%, lanolin 2%, benzocaine 1%) and rubber additives (thiuram-mix 2% and carba-mix 1%). Almost all other substances lie below the 1% limit. There was only one remarkable exception in comparison with the results of most other European studies, namely thiomersal, which is widely distributed as a preservative in vaccines in Austria and climbed to second place, with a sensitization rate of 18%. Although the phenylborate mercurials (historic sensitizations due to topical antiseptics) still reached a surprisingly high incidence of 6%, there were hardly any cases of cross-sensitization with thiomersal. A comparison with the international literature illustrates Austria-specific trends and a change in the spectrum over the past years. Interpretation of patch testing requires great specialist knowledge and experience.

Authors+Show Affiliations

Aberer W
I. Universitäts-Hautklinik, Wien.
Reiter E
No affiliation info available

MeSH

AdolescentAdultAge FactorsAgedAged, 80 and overAllergensChildData Interpretation, StatisticalDermatitis, ContactFemaleHumansMaleMiddle AgedOccupational ExposurePatch TestsSex Factors

Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

2068817

Citation

Aberer, W, and E Reiter. "[Contact Eczema and Epicutaneous Tests--distribution of Allergens and Changes in the Spectrum in Vienna]." Wiener Klinische Wochenschrift, vol. 103, no. 9, 1991, pp. 263-7.
Aberer W, Reiter E. [Contact eczema and epicutaneous tests--distribution of allergens and changes in the spectrum in Vienna]. Wien Klin Wochenschr. 1991;103(9):263-7.
Aberer, W., & Reiter, E. (1991). [Contact eczema and epicutaneous tests--distribution of allergens and changes in the spectrum in Vienna]. Wiener Klinische Wochenschrift, 103(9), 263-7.
Aberer W, Reiter E. [Contact Eczema and Epicutaneous Tests--distribution of Allergens and Changes in the Spectrum in Vienna]. Wien Klin Wochenschr. 1991;103(9):263-7. PubMed PMID: 2068817.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Contact eczema and epicutaneous tests--distribution of allergens and changes in the spectrum in Vienna]. AU - Aberer,W, AU - Reiter,E, PY - 1991/1/1/pubmed PY - 1991/1/1/medline PY - 1991/1/1/entrez SP - 263 EP - 7 JF - Wiener klinische Wochenschrift JO - Wien Klin Wochenschr VL - 103 IS - 9 N2 - Thousands of contact antigens have been defined. It is, however, remarkable that only a small group of substances (15 to 20) have proved to be frequent or otherwise important causes of allergic contact dermatitis. In agreement with reports from comparable centres, metals are high up on the "hitlist" of frequent allergens (nickel 24%, cobalt 9%, chromates 6%), followed by ingredients of cosmetics and toiletries (fragrances 16%, balsam of Peru 10%, Kathon 5%), whilst already way back are topical medicines (neomycin 4%, parabens 3%, lanolin 2%, benzocaine 1%) and rubber additives (thiuram-mix 2% and carba-mix 1%). Almost all other substances lie below the 1% limit. There was only one remarkable exception in comparison with the results of most other European studies, namely thiomersal, which is widely distributed as a preservative in vaccines in Austria and climbed to second place, with a sensitization rate of 18%. Although the phenylborate mercurials (historic sensitizations due to topical antiseptics) still reached a surprisingly high incidence of 6%, there were hardly any cases of cross-sensitization with thiomersal. A comparison with the international literature illustrates Austria-specific trends and a change in the spectrum over the past years. Interpretation of patch testing requires great specialist knowledge and experience. SN - 0043-5325 UR - https://www.unboundmedicine.com/medline/citation/2068817/[Contact_eczema_and_epicutaneous_tests__distribution_of_allergens_and_changes_in_the_spectrum_in_Vienna]_ DB - PRIME DP - Unbound Medicine ER -