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Community-based availability of misoprostol: is it safe?

Abstract

This paper evaluates the safety and acceptability of long-term community-based use of misoprostol for management of postpartum hemorrhage (PPH) in home-births, by comparing deliveries with and without misoprostol use in communities of Kigoma, Tanzania. We administered a standardized survey instrument to women who delivered between August 2004 and May 2007. 940 women completed questionnaires, corresponding to 950 deliveries. Findings showed that the majority of TBAs administered misoprostol at the correct time (76%). Receipt of three or five tablets was most commonly reported (47% and 43% respectively). Misoprostol users were significantly more likely to experience shivering, high temperature, nausea, and vomiting after delivery; adjustment for gynecological history and delivery characteristics revealed no significant differences in experience of symptoms. Misoprostol was highly acceptable to all women surveyed. Misoprostol at the community level is a safe intervention.

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  • Authors+Show Affiliations

    ,

    School of Public Health, University of California, Berkeley, University Hall, Berkeley, CA 94720-7360, USA. ndola@berkeley.edu

    , , ,

    Source

    MeSH

    Adult
    Delivery, Obstetric
    Female
    Humans
    Maternal Health Services
    Midwifery
    Misoprostol
    Oxytocics
    Patient Acceptance of Health Care
    Postpartum Hemorrhage
    Pregnancy
    Premedication
    Tanzania

    Pub Type(s)

    Comparative Study
    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    20690255

    Citation

    Prata, Ndola, et al. "Community-based Availability of Misoprostol: Is It Safe?" African Journal of Reproductive Health, vol. 13, no. 2, 2009, pp. 117-28.
    Prata N, Mbaruku G, Grossman AA, et al. Community-based availability of misoprostol: is it safe? Afr J Reprod Health. 2009;13(2):117-28.
    Prata, N., Mbaruku, G., Grossman, A. A., Holston, M., & Hsieh, K. (2009). Community-based availability of misoprostol: is it safe? African Journal of Reproductive Health, 13(2), pp. 117-28.
    Prata N, et al. Community-based Availability of Misoprostol: Is It Safe. Afr J Reprod Health. 2009;13(2):117-28. PubMed PMID: 20690255.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Community-based availability of misoprostol: is it safe? AU - Prata,Ndola, AU - Mbaruku,Godfrey, AU - Grossman,Amy A, AU - Holston,Martine, AU - Hsieh,Kristina, PY - 2010/8/10/entrez PY - 2009/6/1/pubmed PY - 2010/9/10/medline SP - 117 EP - 28 JF - African journal of reproductive health JO - Afr J Reprod Health VL - 13 IS - 2 N2 - This paper evaluates the safety and acceptability of long-term community-based use of misoprostol for management of postpartum hemorrhage (PPH) in home-births, by comparing deliveries with and without misoprostol use in communities of Kigoma, Tanzania. We administered a standardized survey instrument to women who delivered between August 2004 and May 2007. 940 women completed questionnaires, corresponding to 950 deliveries. Findings showed that the majority of TBAs administered misoprostol at the correct time (76%). Receipt of three or five tablets was most commonly reported (47% and 43% respectively). Misoprostol users were significantly more likely to experience shivering, high temperature, nausea, and vomiting after delivery; adjustment for gynecological history and delivery characteristics revealed no significant differences in experience of symptoms. Misoprostol was highly acceptable to all women surveyed. Misoprostol at the community level is a safe intervention. SN - 1118-4841 UR - https://www.unboundmedicine.com/medline/citation/20690255/Community_based_availability_of_misoprostol:_is_it_safe L2 - https://medlineplus.gov/childbirth.html DB - PRIME DP - Unbound Medicine ER -