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Dietary unsaturated fatty acids and risk of mild cognitive impairment.

Abstract

An increasing body of epidemiological evidence suggested that elevated saturated fatty acids could have negative effects on age-related cognitive decline (ARCD) and mild cognitive impairment (MCI). Furthermore, a clear reduction of risk for cognitive decline has been found in population samples with elevated fish consumption, high intake of monounsaturated fatty acids, and polyunsaturated fatty acids (PUFA), particularly n-3 PUFA. In the present article, on the basis of increasing body of evidence from cross-sectional and longitudinal population-based studies, we discussed the issue of the possible impact of dietary PUFA (both n-6 and n-3) on ARCD, MCI, and Alzheimer's disease.

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  • Authors+Show Affiliations

    ,

    Geriatric Unit and Gerontology-Geriatric Research Laboratory, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.

    , , , ,

    Source

    MeSH

    Cognition Disorders
    Dietary Fats
    Fatty Acids, Unsaturated
    Humans
    Risk

    Pub Type(s)

    Comment
    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    20693628

    Citation

    Panza, Francesco, et al. "Dietary Unsaturated Fatty Acids and Risk of Mild Cognitive Impairment." Journal of Alzheimer's Disease : JAD, vol. 21, no. 3, 2010, pp. 867-70.
    Panza F, Frisardi V, Seripa D, et al. Dietary unsaturated fatty acids and risk of mild cognitive impairment. J Alzheimers Dis. 2010;21(3):867-70.
    Panza, F., Frisardi, V., Seripa, D., Imbimbo, B. P., Pilotto, A., & Solfrizzi, V. (2010). Dietary unsaturated fatty acids and risk of mild cognitive impairment. Journal of Alzheimer's Disease : JAD, 21(3), pp. 867-70. doi:10.3233/JAD-2010-100777.
    Panza F, et al. Dietary Unsaturated Fatty Acids and Risk of Mild Cognitive Impairment. J Alzheimers Dis. 2010;21(3):867-70. PubMed PMID: 20693628.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Dietary unsaturated fatty acids and risk of mild cognitive impairment. AU - Panza,Francesco, AU - Frisardi,Vincenza, AU - Seripa,Davide, AU - Imbimbo,Bruno P, AU - Pilotto,Alberto, AU - Solfrizzi,Vincenzo, PY - 2010/8/10/entrez PY - 2010/8/10/pubmed PY - 2011/1/19/medline SP - 867 EP - 70 JF - Journal of Alzheimer's disease : JAD JO - J. Alzheimers Dis. VL - 21 IS - 3 N2 - An increasing body of epidemiological evidence suggested that elevated saturated fatty acids could have negative effects on age-related cognitive decline (ARCD) and mild cognitive impairment (MCI). Furthermore, a clear reduction of risk for cognitive decline has been found in population samples with elevated fish consumption, high intake of monounsaturated fatty acids, and polyunsaturated fatty acids (PUFA), particularly n-3 PUFA. In the present article, on the basis of increasing body of evidence from cross-sectional and longitudinal population-based studies, we discussed the issue of the possible impact of dietary PUFA (both n-6 and n-3) on ARCD, MCI, and Alzheimer's disease. SN - 1875-8908 UR - https://www.unboundmedicine.com/medline/citation/20693628/Dietary_unsaturated_fatty_acids_and_risk_of_mild_cognitive_impairment_ L2 - https://content.iospress.com/openurl?genre=article&id=doi:10.3233/JAD-2010-100777 DB - PRIME DP - Unbound Medicine ER -