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[Toxic effects of dichloromethane and dichloroethane to Chlorella pyrenoidosa].
Huan Jing Ke Xue. 2010 Jun; 31(6):1655-61.HJ

Abstract

The acute toxic and biochemical effects of dichloromethane and 1,2-dichloroethane to Chlorella pyrenoidosa were assessed. The experimental results showed that dichloromethane and 1, 2-dichloroethane had some inhibition to growth of the algae. With increasing concentration of the organic toxicant, the cell density decreased. The 96 h-EC50 of dichloromethane to Chlorella pyrenoidosa was 550.1 mg/L; the 96 h-EC50 of 1,2-dichloroethane to Chlorella pyrenoidosa was 276.0 mg/L, toxicity of 1,2-dichloroethane is a little stronger than that of dichloromethane; the joint toxicity of two organic toxicants was showed as antagonism. Content of chlorophyll a, activities of superoxide dismutase (SOD), catalase (CAT) and content of malondialdehyde (MDA) in algae had been significantly affected under the organic toxicant exposure. The activities of SOD and CAT were increased at first and then decreased remarkably with the increasing concentration of the organic toxicant, showed as "Bell Shaped Curve". The content of malondialdehyde (MDA) flared up and lipid peroxidant aggregated with the increasing concentration of the organic toxicant. The results suggested that the primary mechanism of two organic toxicants on Chlorella pyrenoidosa cells may be related to oxidation damage of lipid and other biological large molecules caused by dichloromethane and 1,2-dichloroethane.

Authors+Show Affiliations

Wu SJ
College of Biology and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China. wujan28@zjut.edu.cn
Yu X
No affiliation info available
Wu EM
No affiliation info available
Chen JM
No affiliation info available

MeSH

ChlorellaEnvironmental MonitoringEthylene DichloridesMethylene ChlorideSuperoxide DismutaseWater Pollutants, Chemical

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

20698286

Citation

Wu, Shi-Jin, et al. "[Toxic Effects of Dichloromethane and Dichloroethane to Chlorella Pyrenoidosa]." Huan Jing Ke Xue= Huanjing Kexue, vol. 31, no. 6, 2010, pp. 1655-61.
Wu SJ, Yu X, Wu EM, et al. [Toxic effects of dichloromethane and dichloroethane to Chlorella pyrenoidosa]. Huan Jing Ke Xue. 2010;31(6):1655-61.
Wu, S. J., Yu, X., Wu, E. M., & Chen, J. M. (2010). [Toxic effects of dichloromethane and dichloroethane to Chlorella pyrenoidosa]. Huan Jing Ke Xue= Huanjing Kexue, 31(6), 1655-61.
Wu SJ, et al. [Toxic Effects of Dichloromethane and Dichloroethane to Chlorella Pyrenoidosa]. Huan Jing Ke Xue. 2010;31(6):1655-61. PubMed PMID: 20698286.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Toxic effects of dichloromethane and dichloroethane to Chlorella pyrenoidosa]. AU - Wu,Shi-Jin, AU - Yu,Xiang, AU - Wu,Er-Miao, AU - Chen,Jian-Meng, PY - 2010/8/12/entrez PY - 2010/8/12/pubmed PY - 2011/4/26/medline SP - 1655 EP - 61 JF - Huan jing ke xue= Huanjing kexue JO - Huan Jing Ke Xue VL - 31 IS - 6 N2 - The acute toxic and biochemical effects of dichloromethane and 1,2-dichloroethane to Chlorella pyrenoidosa were assessed. The experimental results showed that dichloromethane and 1, 2-dichloroethane had some inhibition to growth of the algae. With increasing concentration of the organic toxicant, the cell density decreased. The 96 h-EC50 of dichloromethane to Chlorella pyrenoidosa was 550.1 mg/L; the 96 h-EC50 of 1,2-dichloroethane to Chlorella pyrenoidosa was 276.0 mg/L, toxicity of 1,2-dichloroethane is a little stronger than that of dichloromethane; the joint toxicity of two organic toxicants was showed as antagonism. Content of chlorophyll a, activities of superoxide dismutase (SOD), catalase (CAT) and content of malondialdehyde (MDA) in algae had been significantly affected under the organic toxicant exposure. The activities of SOD and CAT were increased at first and then decreased remarkably with the increasing concentration of the organic toxicant, showed as "Bell Shaped Curve". The content of malondialdehyde (MDA) flared up and lipid peroxidant aggregated with the increasing concentration of the organic toxicant. The results suggested that the primary mechanism of two organic toxicants on Chlorella pyrenoidosa cells may be related to oxidation damage of lipid and other biological large molecules caused by dichloromethane and 1,2-dichloroethane. SN - 0250-3301 UR - https://www.unboundmedicine.com/medline/citation/20698286/[Toxic_effects_of_dichloromethane_and_dichloroethane_to_Chlorella_pyrenoidosa]_ DB - PRIME DP - Unbound Medicine ER -