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Size selection and concentration of silver nanoparticles by tangential flow ultrafiltration for SERS-based biosensors.
J Am Chem Soc. 2010 Aug 18; 132(32):10970-2.JA

Abstract

A proposed tangential flow ultrafiltration method was compared to the widely used ultracentrifugation method for efficiency and efficacy in concentrating, size selecting, and minimizing the aggregation state of a silver nanoparticle (AgNP) colloid while probing the AgNPs' SERS-based sensing capabilities. The ultrafiltration method proved to be more efficient and more effective and was found to tremendously boost the SERS-based sensing capabilities of these AgNPs through the increased number of homogeneous SERS hot spots available for a biotarget molecule within a minimal focal volume. Future research studies and applications addressing the physiochemical properties or biological impact of AgNPs would greatly benefit from ultrafiltration for its ability to generate monodisperse colloidal nanoparticles, to eliminate excess toxic chemicals from nanoparticle synthesis, and to obtain minimum levels of aggregation during nanoparticle concentration.

Authors+Show Affiliations

Department of Neuroscience, Cell Biology, and Physiology, Wright State University, 3640 Colonel Glenn Highway, Dayton, Ohio 45435, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20698645

Citation

Trefry, John C., et al. "Size Selection and Concentration of Silver Nanoparticles By Tangential Flow Ultrafiltration for SERS-based Biosensors." Journal of the American Chemical Society, vol. 132, no. 32, 2010, pp. 10970-2.
Trefry JC, Monahan JL, Weaver KM, et al. Size selection and concentration of silver nanoparticles by tangential flow ultrafiltration for SERS-based biosensors. J Am Chem Soc. 2010;132(32):10970-2.
Trefry, J. C., Monahan, J. L., Weaver, K. M., Meyerhoefer, A. J., Markopolous, M. M., Arnold, Z. S., Wooley, D. P., & Pavel, I. E. (2010). Size selection and concentration of silver nanoparticles by tangential flow ultrafiltration for SERS-based biosensors. Journal of the American Chemical Society, 132(32), 10970-2. https://doi.org/10.1021/ja103809c
Trefry JC, et al. Size Selection and Concentration of Silver Nanoparticles By Tangential Flow Ultrafiltration for SERS-based Biosensors. J Am Chem Soc. 2010 Aug 18;132(32):10970-2. PubMed PMID: 20698645.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Size selection and concentration of silver nanoparticles by tangential flow ultrafiltration for SERS-based biosensors. AU - Trefry,John C, AU - Monahan,Jennifer L, AU - Weaver,Kent M, AU - Meyerhoefer,Allie J, AU - Markopolous,Marjorie M, AU - Arnold,Zachary S, AU - Wooley,Dawn P, AU - Pavel,Ioana E, PY - 2010/8/12/entrez PY - 2010/8/12/pubmed PY - 2010/12/14/medline SP - 10970 EP - 2 JF - Journal of the American Chemical Society JO - J Am Chem Soc VL - 132 IS - 32 N2 - A proposed tangential flow ultrafiltration method was compared to the widely used ultracentrifugation method for efficiency and efficacy in concentrating, size selecting, and minimizing the aggregation state of a silver nanoparticle (AgNP) colloid while probing the AgNPs' SERS-based sensing capabilities. The ultrafiltration method proved to be more efficient and more effective and was found to tremendously boost the SERS-based sensing capabilities of these AgNPs through the increased number of homogeneous SERS hot spots available for a biotarget molecule within a minimal focal volume. Future research studies and applications addressing the physiochemical properties or biological impact of AgNPs would greatly benefit from ultrafiltration for its ability to generate monodisperse colloidal nanoparticles, to eliminate excess toxic chemicals from nanoparticle synthesis, and to obtain minimum levels of aggregation during nanoparticle concentration. SN - 1520-5126 UR - https://www.unboundmedicine.com/medline/citation/20698645/Size_selection_and_concentration_of_silver_nanoparticles_by_tangential_flow_ultrafiltration_for_SERS_based_biosensors_ L2 - https://doi.org/10.1021/ja103809c DB - PRIME DP - Unbound Medicine ER -