TY - JOUR T1 - [Flavonoids and phenolic acid derivatives from flos farfarae]. AU - Wu,Di, AU - Zhang,Mian, AU - Zhang,Chaofeng, AU - Wang,Zhengtao, PY - 2010/8/17/entrez PY - 2010/8/17/pubmed PY - 2010/9/18/medline SP - 1142 EP - 4 JF - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica JO - Zhongguo Zhong Yao Za Zhi VL - 35 IS - 9 N2 - OBJECTIVE: To investigate the chemical constituents of the flower buds of Tussilago farfara. METHOD: The chemical constituents were isolated by silica gel and Sephadex LH-20 column chromatography, and structurally elucidated by spectral evidence together with physiochemical properties. RESULT: Seven flavonoids, quercetin (1), quercetin-3-O-beta-D-glucopyranoside (2), quercetin-4'-O-beta-D-glucopyranoside (3), hyperoside (4), rutin (5), kaempferol (6), kaempferol-3-O-alpha-L-rhamnopyranosyl-(1-6)-beta-D-glucopyranoside (7), together with eight phenolic acid derivatives, caffeic acid (8), methyl caffeate (9), ethyl caffeate (10), (E)-2,5-dihydroxycinnamic acid (11), 3,4-di-O-caffeoylquinic acid (12), 4,5-di-O-caffeoylquinic acid (13), methyl4,5-di-O-caffeoylquinate (14) and chlorogenic acid (15) were isolated from the flower buds of Tussilago farfara. CONCLUSION: Compounds 7, 9-14 are isolated from this plant, also from this genus, for the first time. SN - 1001-5302 UR - https://www.unboundmedicine.com/medline/citation/20707069/[Flavonoids_and_phenolic_acid_derivatives_from_flos_farfarae]_ DB - PRIME DP - Unbound Medicine ER -