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The correlation of osteoporosis to clinical features: a study of 4382 female cases of a hospital cohort with musculoskeletal symptoms in southwest China.
BMC Musculoskelet Disord. 2010 Aug 16; 11:183.BM

Abstract

BACKGROUND

By analyzing the clinical features and risk factors in female patients with musculoskeletal symptoms of Southwest China, this report presents the initial analysis of characteristics in this region and compared with international evaluative criteria.

METHODS

Diagnosis of osteoporosis (OP) was made in female hospital patients age > or = 18 years admitted from January 1998 to December 2008 according to WHO definition. Case data were analyzed by symptoms, age, disease course and risk factors to reveal correlation with diagnosis of OP. Logistic regression was used to identify the risks of osteoporosis.

RESULTS

A total of 4382 patients were included in the analysis of the baseline characteristics, among which 1455 in the OP group and 2927 in the non-OP group. The morbidity of OP is significantly increased in females' > or = 50 years. Both groups had symptoms related to pain and numbness; no significant difference was found in reported upper and lower back pain, or leg pain between two groups (p > 0.05). Neck, shoulder and arm pain, leg and arm numbness were more common in the non-osteoporosis group (p < 0.05, OR < 1, and upper limit of 95% CI of OR < 1). Hypertension, diabetes, hyperostosis were major risk factors for the patients with OP. The most common lifestyle-related risk factors for osteoporosis were smoking, body mass index, lack of physical activity and menopause.

CONCLUSIONS

The present study offers the first reference data of the relationship between epidemiologic distribution of osteoporosis and associated factors in adults Chinese women. These findings provide a theoretical basis for its prevention and treatment in developing country.

Links

PMC Free PDF

Authors+Show Affiliations

Li S
Department of Rehabilitation Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
He H
No affiliation info available
Ding M
No affiliation info available
He C
No affiliation info available

MeSH

AdultAsian PeopleChinaCohort StudiesComorbidityFemaleHospitalsHumansMiddle AgedMusculoskeletal DiseasesObesityOsteoporosis, PostmenopausalPainPrevalenceRetrospective StudiesRisk FactorsSedentary Behavior

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20712872

Citation

Li, Shasha, et al. "The Correlation of Osteoporosis to Clinical Features: a Study of 4382 Female Cases of a Hospital Cohort With Musculoskeletal Symptoms in Southwest China." BMC Musculoskeletal Disorders, vol. 11, 2010, p. 183.
Li S, He H, Ding M, et al. The correlation of osteoporosis to clinical features: a study of 4382 female cases of a hospital cohort with musculoskeletal symptoms in southwest China. BMC Musculoskelet Disord. 2010;11:183.
Li, S., He, H., Ding, M., & He, C. (2010). The correlation of osteoporosis to clinical features: a study of 4382 female cases of a hospital cohort with musculoskeletal symptoms in southwest China. BMC Musculoskeletal Disorders, 11, 183. https://doi.org/10.1186/1471-2474-11-183
Li S, et al. The Correlation of Osteoporosis to Clinical Features: a Study of 4382 Female Cases of a Hospital Cohort With Musculoskeletal Symptoms in Southwest China. BMC Musculoskelet Disord. 2010 Aug 16;11:183. PubMed PMID: 20712872.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The correlation of osteoporosis to clinical features: a study of 4382 female cases of a hospital cohort with musculoskeletal symptoms in southwest China. AU - Li,Shasha, AU - He,Hongchen, AU - Ding,Mingfu, AU - He,Chengqi, Y1 - 2010/08/16/ PY - 2010/03/20/received PY - 2010/08/16/accepted PY - 2010/8/18/entrez PY - 2010/8/18/pubmed PY - 2011/2/4/medline SP - 183 EP - 183 JF - BMC musculoskeletal disorders JO - BMC Musculoskelet Disord VL - 11 N2 - BACKGROUND: By analyzing the clinical features and risk factors in female patients with musculoskeletal symptoms of Southwest China, this report presents the initial analysis of characteristics in this region and compared with international evaluative criteria. METHODS: Diagnosis of osteoporosis (OP) was made in female hospital patients age > or = 18 years admitted from January 1998 to December 2008 according to WHO definition. Case data were analyzed by symptoms, age, disease course and risk factors to reveal correlation with diagnosis of OP. Logistic regression was used to identify the risks of osteoporosis. RESULTS: A total of 4382 patients were included in the analysis of the baseline characteristics, among which 1455 in the OP group and 2927 in the non-OP group. The morbidity of OP is significantly increased in females' > or = 50 years. Both groups had symptoms related to pain and numbness; no significant difference was found in reported upper and lower back pain, or leg pain between two groups (p > 0.05). Neck, shoulder and arm pain, leg and arm numbness were more common in the non-osteoporosis group (p < 0.05, OR < 1, and upper limit of 95% CI of OR < 1). Hypertension, diabetes, hyperostosis were major risk factors for the patients with OP. The most common lifestyle-related risk factors for osteoporosis were smoking, body mass index, lack of physical activity and menopause. CONCLUSIONS: The present study offers the first reference data of the relationship between epidemiologic distribution of osteoporosis and associated factors in adults Chinese women. These findings provide a theoretical basis for its prevention and treatment in developing country. SN - 1471-2474 UR - https://www.unboundmedicine.com/medline/citation/20712872/The_correlation_of_osteoporosis_to_clinical_features:_a_study_of_4382_female_cases_of_a_hospital_cohort_with_musculoskeletal_symptoms_in_southwest_China_ DB - PRIME DP - Unbound Medicine ER -