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Alcohol intake and risk of incident psoriasis in US women: a prospective study.

Abstract

OBJECTIVES

To evaluate the independent association between alcohol consumption and risk of developing psoriasis and to determine if this risk is associated with different types of alcoholic beverages.

DESIGN

A prospective study of female nurses who were followed up from 1991 to 2005.

SETTING

Nurses' Health Study II, a cohort of 116,671 US women aged 27 to 44 years in 1991.

PARTICIPANTS

The study population included 82,869 women who reported amount and type of alcohol intake on biennial questionnaires. We excluded participants with a history of psoriasis prior to 1991.

MAIN OUTCOME MEASURE

Self-report of incident physician-diagnosed psoriasis. For a sensitivity analysis, we had a subset of confirmed psoriasis cases.

RESULTS

There were 1150 cases of incident psoriasis, 1069 of which were used for analysis. Compared with women who did not drink alcohol, the multivariate relative risk (RR) of psoriasis was 1.72 (95% confidence interval [CI], 1.15-2.57) for an alcohol consumption of 2.3 drinks/wk or more. When examined by type of alcoholic beverage, there was an association between psoriasis and nonlight beer intake (multivariate RR for ≥ 5 drinks/wk, 1.76; 95% CI, 1.15-2.69); light beer, red wine, white wine, and liquor were not significantly associated with psoriasis risk. The association with nonlight beer intake became stronger in a subset of confirmed psoriasis cases (multivariate RR for ≥ 5 drinks/wk, 2.29; 95% CI, 1.36-3.85).

CONCLUSIONS

Nonlight beer intake is associated with an increased risk of developing psoriasis among women. Other alcoholic beverages did not increase the risk of psoriasis in this study.

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  • Authors+Show Affiliations

    ,

    Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA. abrar.qureshi@channing.harvard.edu

    , , ,

    Source

    Archives of dermatology 146:12 2010 Dec pg 1364-9

    MeSH

    Adult
    Alcohol Drinking
    Alcoholic Beverages
    Female
    Humans
    Incidence
    Prospective Studies
    Psoriasis
    Risk Factors
    Surveys and Questionnaires
    United States

    Pub Type(s)

    Comparative Study
    Journal Article
    Research Support, N.I.H., Extramural

    Language

    eng

    PubMed ID

    20713772

    Citation

    Qureshi, Abrar A., et al. "Alcohol Intake and Risk of Incident Psoriasis in US Women: a Prospective Study." Archives of Dermatology, vol. 146, no. 12, 2010, pp. 1364-9.
    Qureshi AA, Dominguez PL, Choi HK, et al. Alcohol intake and risk of incident psoriasis in US women: a prospective study. Arch Dermatol. 2010;146(12):1364-9.
    Qureshi, A. A., Dominguez, P. L., Choi, H. K., Han, J., & Curhan, G. (2010). Alcohol intake and risk of incident psoriasis in US women: a prospective study. Archives of Dermatology, 146(12), pp. 1364-9. doi:10.1001/archdermatol.2010.204.
    Qureshi AA, et al. Alcohol Intake and Risk of Incident Psoriasis in US Women: a Prospective Study. Arch Dermatol. 2010;146(12):1364-9. PubMed PMID: 20713772.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Alcohol intake and risk of incident psoriasis in US women: a prospective study. AU - Qureshi,Abrar A, AU - Dominguez,Patrick L, AU - Choi,Hyon K, AU - Han,Jiali, AU - Curhan,Gary, Y1 - 2010/08/16/ PY - 2010/8/18/entrez PY - 2010/8/18/pubmed PY - 2011/3/16/medline SP - 1364 EP - 9 JF - Archives of dermatology JO - Arch Dermatol VL - 146 IS - 12 N2 - OBJECTIVES: To evaluate the independent association between alcohol consumption and risk of developing psoriasis and to determine if this risk is associated with different types of alcoholic beverages. DESIGN: A prospective study of female nurses who were followed up from 1991 to 2005. SETTING: Nurses' Health Study II, a cohort of 116,671 US women aged 27 to 44 years in 1991. PARTICIPANTS: The study population included 82,869 women who reported amount and type of alcohol intake on biennial questionnaires. We excluded participants with a history of psoriasis prior to 1991. MAIN OUTCOME MEASURE: Self-report of incident physician-diagnosed psoriasis. For a sensitivity analysis, we had a subset of confirmed psoriasis cases. RESULTS: There were 1150 cases of incident psoriasis, 1069 of which were used for analysis. Compared with women who did not drink alcohol, the multivariate relative risk (RR) of psoriasis was 1.72 (95% confidence interval [CI], 1.15-2.57) for an alcohol consumption of 2.3 drinks/wk or more. When examined by type of alcoholic beverage, there was an association between psoriasis and nonlight beer intake (multivariate RR for ≥ 5 drinks/wk, 1.76; 95% CI, 1.15-2.69); light beer, red wine, white wine, and liquor were not significantly associated with psoriasis risk. The association with nonlight beer intake became stronger in a subset of confirmed psoriasis cases (multivariate RR for ≥ 5 drinks/wk, 2.29; 95% CI, 1.36-3.85). CONCLUSIONS: Nonlight beer intake is associated with an increased risk of developing psoriasis among women. Other alcoholic beverages did not increase the risk of psoriasis in this study. SN - 1538-3652 UR - https://www.unboundmedicine.com/medline/citation/20713772/full_citation L2 - https://jamanetwork.com/journals/jamadermatology/fullarticle/10.1001/archdermatol.2010.204 DB - PRIME DP - Unbound Medicine ER -