Enantioselective α-Chlorination of Aldehydes with Recyclable Fluorous (S)-Pyrrolidine-Thiourea Bifunctional Organocatalyst.Synlett. 2010 Jan 01; 3(2010):433-436.S
Abstract
A novel fluorous (S)-pyrrolidine-thiourea bifunctional organocatalyst is prepared. The catalyst shows good activity and enantioselectivity for direct α-chlorination of aldehydes using N-chlorosuccinimide (NCS) as the chlorine source. It can be recovered from the reaction mixture by fluorous solid-phase extraction with excellent purity for direct reuse.
Links
Pub Type(s)
Journal Article
Language
eng
PubMed ID
20717504
Citation
Wang, Liang, et al. "Enantioselective α-Chlorination of Aldehydes With Recyclable Fluorous (S)-Pyrrolidine-Thiourea Bifunctional Organocatalyst." Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry, vol. 3, no. 2010, 2010, pp. 433-436.
Wang L, Cai C, Curran DP, et al. Enantioselective α-Chlorination of Aldehydes with Recyclable Fluorous (S)-Pyrrolidine-Thiourea Bifunctional Organocatalyst. Synlett. 2010;3(2010):433-436.
Wang, L., Cai, C., Curran, D. P., & Zhang, W. (2010). Enantioselective α-Chlorination of Aldehydes with Recyclable Fluorous (S)-Pyrrolidine-Thiourea Bifunctional Organocatalyst. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry, 3(2010), 433-436.
Wang L, et al. Enantioselective α-Chlorination of Aldehydes With Recyclable Fluorous (S)-Pyrrolidine-Thiourea Bifunctional Organocatalyst. Synlett. 2010 Jan 1;3(2010):433-436. PubMed PMID: 20717504.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Enantioselective α-Chlorination of Aldehydes with Recyclable Fluorous (S)-Pyrrolidine-Thiourea Bifunctional Organocatalyst.
AU - Wang,Liang,
AU - Cai,Chun,
AU - Curran,Dennis P,
AU - Zhang,Wei,
PY - 2010/8/19/entrez
PY - 2010/8/19/pubmed
PY - 2010/8/19/medline
SP - 433
EP - 436
JF - Synlett : accounts and rapid communications in synthetic organic chemistry
JO - Synlett
VL - 3
IS - 2010
N2 - A novel fluorous (S)-pyrrolidine-thiourea bifunctional organocatalyst is prepared. The catalyst shows good activity and enantioselectivity for direct α-chlorination of aldehydes using N-chlorosuccinimide (NCS) as the chlorine source. It can be recovered from the reaction mixture by fluorous solid-phase extraction with excellent purity for direct reuse.
SN - 0936-5214
UR - https://www.unboundmedicine.com/medline/citation/20717504/Enantioselective_α_Chlorination_of_Aldehydes_with_Recyclable_Fluorous__S__Pyrrolidine_Thiourea_Bifunctional_Organocatalyst_
L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20717504/
DB - PRIME
DP - Unbound Medicine
ER -
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