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Three cases of acute fatty liver of pregnancy: postpartum clinical course depends on interval between onset of symptoms and termination of pregnancy.
J Matern Fetal Neonatal Med. 2010 Sep; 23(9):1047-9.JM

Abstract

We report our experience with three cases of acute fatty liver of pregnancy. Case 1 complained of hydrodipsia 4 days before delivery. Case 2 presented with nausea, vomiting and dizziness 6 days before delivery. Case 3 developed loss of appetite and general fatigue with jaundice 10 days before delivery. They underwent termination of pregnancy after diagnosis was made. Case 3 still developed hepatic encephalopathy, and finally she required liver transplantation. We hypothesise that the interval between the onset of symptoms and termination of pregnancy is an important factor for acuity of the disorder and patient morbidity or mortality.

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Authors+Show Affiliations

Aso K
Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Hojo S
No affiliation info available
Yumoto Y
No affiliation info available
Fukushima K
No affiliation info available
Miyazaki M
No affiliation info available
Kotoh K
No affiliation info available
Wake N
No affiliation info available

MeSH

Acute DiseaseAdultDelivery, ObstetricFatty LiverFemaleGestational AgeHumansPostpartum PeriodPregnancyPregnancy ComplicationsPregnancy OutcomeTime FactorsYoung Adult

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

20718581

Citation

Aso, Kaai, et al. "Three Cases of Acute Fatty Liver of Pregnancy: Postpartum Clinical Course Depends On Interval Between Onset of Symptoms and Termination of Pregnancy." The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, vol. 23, no. 9, 2010, pp. 1047-9.
Aso K, Hojo S, Yumoto Y, et al. Three cases of acute fatty liver of pregnancy: postpartum clinical course depends on interval between onset of symptoms and termination of pregnancy. J Matern Fetal Neonatal Med. 2010;23(9):1047-9.
Aso, K., Hojo, S., Yumoto, Y., Fukushima, K., Miyazaki, M., Kotoh, K., & Wake, N. (2010). Three cases of acute fatty liver of pregnancy: postpartum clinical course depends on interval between onset of symptoms and termination of pregnancy. The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 23(9), 1047-9. https://doi.org/10.3109/14767050903353232
Aso K, et al. Three Cases of Acute Fatty Liver of Pregnancy: Postpartum Clinical Course Depends On Interval Between Onset of Symptoms and Termination of Pregnancy. J Matern Fetal Neonatal Med. 2010;23(9):1047-9. PubMed PMID: 20718581.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Three cases of acute fatty liver of pregnancy: postpartum clinical course depends on interval between onset of symptoms and termination of pregnancy. AU - Aso,Kaai, AU - Hojo,Satoshi, AU - Yumoto,Yasuo, AU - Fukushima,Kotaro, AU - Miyazaki,Masayuki, AU - Kotoh,Kazuhiro, AU - Wake,Norio, PY - 2010/8/20/entrez PY - 2010/8/20/pubmed PY - 2010/12/16/medline SP - 1047 EP - 9 JF - The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians JO - J Matern Fetal Neonatal Med VL - 23 IS - 9 N2 - We report our experience with three cases of acute fatty liver of pregnancy. Case 1 complained of hydrodipsia 4 days before delivery. Case 2 presented with nausea, vomiting and dizziness 6 days before delivery. Case 3 developed loss of appetite and general fatigue with jaundice 10 days before delivery. They underwent termination of pregnancy after diagnosis was made. Case 3 still developed hepatic encephalopathy, and finally she required liver transplantation. We hypothesise that the interval between the onset of symptoms and termination of pregnancy is an important factor for acuity of the disorder and patient morbidity or mortality. SN - 1476-4954 UR - https://www.unboundmedicine.com/medline/citation/20718581/Three_cases_of_acute_fatty_liver_of_pregnancy:_postpartum_clinical_course_depends_on_interval_between_onset_of_symptoms_and_termination_of_pregnancy_ L2 - https://www.tandfonline.com/doi/full/10.3109/14767050903353232 DB - PRIME DP - Unbound Medicine ER -