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Copper(I)-secondary diamine complex-catalyzed enantioselective conjugate boration of linear β,β-disubstituted enones.
Org Lett. 2010 Sep 17; 12(18):4098-101.OL

Abstract

A copper(I)-chiral secondary diamine (L-e) complex catalyzes an enantioselective conjugate boration of β,β-disubstituted enones in high yields and up to 99% ee. Product chiral tertiary organoboronates can be converted to enantiomerically enriched cross-aldol products between ketones without any racemization.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Chen IH
Institute of Microbial Chemistry, Tokyo, Kamiosaki 3-14-23, Shinagawa-ku, Tokyo 141-0021, Japan.
Kanai M
No affiliation info available
Shibasaki M
No affiliation info available

MeSH

Boron CompoundsCatalysisCopperDiaminesMolecular StructureStereoisomerism

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20722382

Citation

Chen, I-Hon, et al. "Copper(I)-secondary Diamine Complex-catalyzed Enantioselective Conjugate Boration of Linear Β,β-disubstituted Enones." Organic Letters, vol. 12, no. 18, 2010, pp. 4098-101.
Chen IH, Kanai M, Shibasaki M. Copper(I)-secondary diamine complex-catalyzed enantioselective conjugate boration of linear β,β-disubstituted enones. Org Lett. 2010;12(18):4098-101.
Chen, I. H., Kanai, M., & Shibasaki, M. (2010). Copper(I)-secondary diamine complex-catalyzed enantioselective conjugate boration of linear β,β-disubstituted enones. Organic Letters, 12(18), 4098-101. https://doi.org/10.1021/ol101691p
Chen IH, Kanai M, Shibasaki M. Copper(I)-secondary Diamine Complex-catalyzed Enantioselective Conjugate Boration of Linear Β,β-disubstituted Enones. Org Lett. 2010 Sep 17;12(18):4098-101. PubMed PMID: 20722382.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Copper(I)-secondary diamine complex-catalyzed enantioselective conjugate boration of linear β,β-disubstituted enones. AU - Chen,I-Hon, AU - Kanai,Motomu, AU - Shibasaki,Masakatsu, PY - 2010/8/21/entrez PY - 2010/8/21/pubmed PY - 2010/12/22/medline SP - 4098 EP - 101 JF - Organic letters JO - Org Lett VL - 12 IS - 18 N2 - A copper(I)-chiral secondary diamine (L-e) complex catalyzes an enantioselective conjugate boration of β,β-disubstituted enones in high yields and up to 99% ee. Product chiral tertiary organoboronates can be converted to enantiomerically enriched cross-aldol products between ketones without any racemization. SN - 1523-7052 UR - https://www.unboundmedicine.com/medline/citation/20722382/Copper_I__secondary_diamine_complex_catalyzed_enantioselective_conjugate_boration_of_linear_ββ_disubstituted_enones_ L2 - https://doi.org/10.1021/ol101691p DB - PRIME DP - Unbound Medicine ER -