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Triterpene saponins from Cyclamen persicum.
Nat Prod Commun. 2010 Jul; 5(7):1023-5.NP

Abstract

A new triterpene saponin 3-O-beta-D-glucopyranosyl-(1 --> 4)-alpha-L-arabinopyranosyl-16alpha-hydroxy-13beta,28-epoxy-oleanan-30-al (1), along with four known triterpene glycosides (2-5) were isolated from Cyclamen persicum. Their structures were characterized by a combination of 1D- and 2D-NMR (1H-1H COSY, TOCSY, NOESY, HSQC, and HMBC) and MS spectrocopic data. The cytotoxicity of compounds 2 and 4 was evaluated using two human colon cancer cell lines HT-29 and HCT 116.

Authors+Show Affiliations

Mihci-Gaidi G
Laboratoire de Pharmacognosie, Unité de Molécules d'Intérĉt Biologique (UMIB UPRES EA 3660), Faculté de Pharmacie, Universitá de Bourgogne, BP 87900, 21079 Dijon Cedex, France.
Pertuit D
No affiliation info available
Miyamoto T
No affiliation info available
Mirjolet JF
No affiliation info available
Duchamp O
No affiliation info available
Mitaine-Offer AC
No affiliation info available
Lacaille-Dubois MA
No affiliation info available

MeSH

Cell Line, TumorCyclamenHumansInhibitory Concentration 50Magnetic Resonance SpectroscopyMolecular StructureSaponinsTriterpenes

Pub Type(s)

Journal Article

Language

eng

PubMed ID

20734932

Citation

Mihci-Gaidi, Ghezala, et al. "Triterpene Saponins From Cyclamen Persicum." Natural Product Communications, vol. 5, no. 7, 2010, pp. 1023-5.
Mihci-Gaidi G, Pertuit D, Miyamoto T, et al. Triterpene saponins from Cyclamen persicum. Nat Prod Commun. 2010;5(7):1023-5.
Mihci-Gaidi, G., Pertuit, D., Miyamoto, T., Mirjolet, J. F., Duchamp, O., Mitaine-Offer, A. C., & Lacaille-Dubois, M. A. (2010). Triterpene saponins from Cyclamen persicum. Natural Product Communications, 5(7), 1023-5.
Mihci-Gaidi G, et al. Triterpene Saponins From Cyclamen Persicum. Nat Prod Commun. 2010;5(7):1023-5. PubMed PMID: 20734932.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Triterpene saponins from Cyclamen persicum. AU - Mihci-Gaidi,Ghezala, AU - Pertuit,David, AU - Miyamoto,Tomofumi, AU - Mirjolet,Jean-François, AU - Duchamp,Olivier, AU - Mitaine-Offer,Anne-Claire, AU - Lacaille-Dubois,Marie-Aleth, PY - 2010/8/26/entrez PY - 2010/8/26/pubmed PY - 2010/9/18/medline SP - 1023 EP - 5 JF - Natural product communications JO - Nat Prod Commun VL - 5 IS - 7 N2 - A new triterpene saponin 3-O-beta-D-glucopyranosyl-(1 --> 4)-alpha-L-arabinopyranosyl-16alpha-hydroxy-13beta,28-epoxy-oleanan-30-al (1), along with four known triterpene glycosides (2-5) were isolated from Cyclamen persicum. Their structures were characterized by a combination of 1D- and 2D-NMR (1H-1H COSY, TOCSY, NOESY, HSQC, and HMBC) and MS spectrocopic data. The cytotoxicity of compounds 2 and 4 was evaluated using two human colon cancer cell lines HT-29 and HCT 116. SN - 1934-578X UR - https://www.unboundmedicine.com/medline/citation/20734932/Triterpene_saponins_from_Cyclamen_persicum_ DB - PRIME DP - Unbound Medicine ER -