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Chemical composition, antibacterial and antioxidant activity of the essential oil of Bupleurum longiradiatum.
Nat Prod Commun. 2010 Jul; 5(7):1139-42.NP

Abstract

The essential oil from the roots of Bupleurum longiradiatum, obtained by hydro-distillation was analyzed by gas chromatography/mass spectrometry (GC/MS) and evaluated for antimicrobial activity and antioxidant activity. Fifty-one compounds were identified, representing 99.3% of the total oil. The major constituents were thymol (7.0%), butylidene phthalide (6.8%), 5-indolol (5.6%), heptanal (5.3%), 4-hydroxy-2-methylacetophenone (5.3%), 4,5-diethyl-octane (5.3%), bormeol (5.1%) and hexanoic acid (5.1%). The oil was tested against 4 bacteria at different concentrations using disc diffusion and 96-well dilution methods. The inhibition zones and minimum inhibitory concentration values for bacterial strains were in the range of 7.0-18.0 mm and 250 -500 microg/mL, respectively. The in vitro antioxidant activity was assessed by DPPH radical scavenging and inhibition of lipid peroxidation methods. The oil showed a potent free radical scavenging activity, as evidenced by the low IC50 value for DPPH radical (566.2 microg/mL) and inhibition of lipid peroxidation (induced by FeSO4, H2O2 and CCl4) with IC50 values of 275.2 microg/mL, 296.9 microg/mL and 118.7 microg/mL, respectively.

Authors+Show Affiliations

Shi B
Institute of Pesticide, Northwest A&F University, Yangling, Shaanxi 712100, China.
Liu W
No affiliation info available
Wei SP
No affiliation info available
Wu WJ
No affiliation info available

MeSH

Anti-Bacterial AgentsAntioxidantsBacteriaBupleurumFree Radical ScavengersMicrobial Sensitivity TestsOils, Volatile

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

20734959

Citation

Shi, Baojun, et al. "Chemical Composition, Antibacterial and Antioxidant Activity of the Essential Oil of Bupleurum Longiradiatum." Natural Product Communications, vol. 5, no. 7, 2010, pp. 1139-42.
Shi B, Liu W, Wei SP, et al. Chemical composition, antibacterial and antioxidant activity of the essential oil of Bupleurum longiradiatum. Nat Prod Commun. 2010;5(7):1139-42.
Shi, B., Liu, W., Wei, S. P., & Wu, W. J. (2010). Chemical composition, antibacterial and antioxidant activity of the essential oil of Bupleurum longiradiatum. Natural Product Communications, 5(7), 1139-42.
Shi B, et al. Chemical Composition, Antibacterial and Antioxidant Activity of the Essential Oil of Bupleurum Longiradiatum. Nat Prod Commun. 2010;5(7):1139-42. PubMed PMID: 20734959.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chemical composition, antibacterial and antioxidant activity of the essential oil of Bupleurum longiradiatum. AU - Shi,Baojun, AU - Liu,Wei, AU - Wei,Shao-Peng, AU - Wu,Wen-Jun, PY - 2010/8/26/entrez PY - 2010/8/26/pubmed PY - 2010/9/18/medline SP - 1139 EP - 42 JF - Natural product communications JO - Nat Prod Commun VL - 5 IS - 7 N2 - The essential oil from the roots of Bupleurum longiradiatum, obtained by hydro-distillation was analyzed by gas chromatography/mass spectrometry (GC/MS) and evaluated for antimicrobial activity and antioxidant activity. Fifty-one compounds were identified, representing 99.3% of the total oil. The major constituents were thymol (7.0%), butylidene phthalide (6.8%), 5-indolol (5.6%), heptanal (5.3%), 4-hydroxy-2-methylacetophenone (5.3%), 4,5-diethyl-octane (5.3%), bormeol (5.1%) and hexanoic acid (5.1%). The oil was tested against 4 bacteria at different concentrations using disc diffusion and 96-well dilution methods. The inhibition zones and minimum inhibitory concentration values for bacterial strains were in the range of 7.0-18.0 mm and 250 -500 microg/mL, respectively. The in vitro antioxidant activity was assessed by DPPH radical scavenging and inhibition of lipid peroxidation methods. The oil showed a potent free radical scavenging activity, as evidenced by the low IC50 value for DPPH radical (566.2 microg/mL) and inhibition of lipid peroxidation (induced by FeSO4, H2O2 and CCl4) with IC50 values of 275.2 microg/mL, 296.9 microg/mL and 118.7 microg/mL, respectively. SN - 1934-578X UR - https://www.unboundmedicine.com/medline/citation/20734959/Chemical_composition_antibacterial_and_antioxidant_activity_of_the_essential_oil_of_Bupleurum_longiradiatum_ L2 - https://medlineplus.gov/antibiotics.html DB - PRIME DP - Unbound Medicine ER -