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Drug-induced subacute cutaneous lupus erythematosus associated with omeprazole.
Clin Exp Dermatol. 2011 Apr; 36(3):281-3.CE

Abstract

Subacute cutaneous lupus erythematosus (SCLE) is characterized by annular scaly erythematous plaques in a photosensitive distribution, and the presence of anti-Ro (SSA) and/or anti-La (SSB) antibodies. Most cases of SCLE are idiopathic, but occasional cases may be drug-induced or associated with a hereditary deficiency of complement components. We report two cases of drug-induced SCLE precipitated by the proton pump inhibitor, omeprazole. Drug-induced disease should be considered in all atypical or extensive cases of SCLE, especially in elderly patients.

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Authors+Show Affiliations

Toms-Whittle LM
Department of Dermatology, Great Western Hospital NHS Foundation Trust, Swindon, Wiltshire, UK.
John LH
No affiliation info available
Buckley DA
No affiliation info available

MeSH

AgedAged, 80 and overAnti-Ulcer AgentsDrug EruptionsFemaleHumansLupus Erythematosus, CutaneousOmeprazoleProton Pump Inhibitors

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

20738320

Citation

Toms-Whittle, L M., et al. "Drug-induced Subacute Cutaneous Lupus Erythematosus Associated With Omeprazole." Clinical and Experimental Dermatology, vol. 36, no. 3, 2011, pp. 281-3.
Toms-Whittle LM, John LH, Buckley DA. Drug-induced subacute cutaneous lupus erythematosus associated with omeprazole. Clin Exp Dermatol. 2011;36(3):281-3.
Toms-Whittle, L. M., John, L. H., & Buckley, D. A. (2011). Drug-induced subacute cutaneous lupus erythematosus associated with omeprazole. Clinical and Experimental Dermatology, 36(3), 281-3. https://doi.org/10.1111/j.1365-2230.2010.03926.x
Toms-Whittle LM, John LH, Buckley DA. Drug-induced Subacute Cutaneous Lupus Erythematosus Associated With Omeprazole. Clin Exp Dermatol. 2011;36(3):281-3. PubMed PMID: 20738320.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Drug-induced subacute cutaneous lupus erythematosus associated with omeprazole. AU - Toms-Whittle,L M, AU - John,L H, AU - Buckley,D A, Y1 - 2010/08/25/ PY - 2010/8/27/entrez PY - 2010/8/27/pubmed PY - 2011/5/25/medline SP - 281 EP - 3 JF - Clinical and experimental dermatology JO - Clin Exp Dermatol VL - 36 IS - 3 N2 - Subacute cutaneous lupus erythematosus (SCLE) is characterized by annular scaly erythematous plaques in a photosensitive distribution, and the presence of anti-Ro (SSA) and/or anti-La (SSB) antibodies. Most cases of SCLE are idiopathic, but occasional cases may be drug-induced or associated with a hereditary deficiency of complement components. We report two cases of drug-induced SCLE precipitated by the proton pump inhibitor, omeprazole. Drug-induced disease should be considered in all atypical or extensive cases of SCLE, especially in elderly patients. SN - 1365-2230 UR - https://www.unboundmedicine.com/medline/citation/20738320/Drug_induced_subacute_cutaneous_lupus_erythematosus_associated_with_omeprazole_ L2 - https://doi.org/10.1111/j.1365-2230.2010.03926.x DB - PRIME DP - Unbound Medicine ER -