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[Parkinson's disease: Is there a strong environmental contribution?].
Rev Neurol (Paris) 2010; 166(10):757-63RN

Abstract

Parkinson's disease (PD) is the most common cause of the parkinsonian syndromes and the most frequent neurodegenerative disease after Alzheimer's disease. Only a minority of PD cases is due to a single factor, in particular a genetic mutation. In the large majority of cases, it is considered that PD is a complex or multifactorial disease that results from the effect of multiple risk or protective factors, either genetic or environmental, and, possibly, from their interaction. Epidemiological studies, through a variety of approaches, have brought important evidence in favour of the contribution of environmental factors to the etiology of PD. In this review, we will present current evidence by focusing on specific illustrative examples.

Authors+Show Affiliations

Inserm, Unité 708, Service de Neuroépidémiologie, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital, 75651 Paris Cedex 13, France. alexis.elbaz@upmc.frNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

fre

PubMed ID

20739042

Citation

Elbaz, A, and F Moisan. "[Parkinson's Disease: Is There a Strong Environmental Contribution?]." Revue Neurologique, vol. 166, no. 10, 2010, pp. 757-63.
Elbaz A, Moisan F. [Parkinson's disease: Is there a strong environmental contribution?]. Rev Neurol (Paris). 2010;166(10):757-63.
Elbaz, A., & Moisan, F. (2010). [Parkinson's disease: Is there a strong environmental contribution?]. Revue Neurologique, 166(10), pp. 757-63. doi:10.1016/j.neurol.2010.07.008.
Elbaz A, Moisan F. [Parkinson's Disease: Is There a Strong Environmental Contribution?]. Rev Neurol (Paris). 2010;166(10):757-63. PubMed PMID: 20739042.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Parkinson's disease: Is there a strong environmental contribution?]. AU - Elbaz,A, AU - Moisan,F, Y1 - 2010/08/23/ PY - 2010/07/15/received PY - 2010/07/19/accepted PY - 2010/8/27/entrez PY - 2010/8/27/pubmed PY - 2010/12/14/medline SP - 757 EP - 63 JF - Revue neurologique JO - Rev. Neurol. (Paris) VL - 166 IS - 10 N2 - Parkinson's disease (PD) is the most common cause of the parkinsonian syndromes and the most frequent neurodegenerative disease after Alzheimer's disease. Only a minority of PD cases is due to a single factor, in particular a genetic mutation. In the large majority of cases, it is considered that PD is a complex or multifactorial disease that results from the effect of multiple risk or protective factors, either genetic or environmental, and, possibly, from their interaction. Epidemiological studies, through a variety of approaches, have brought important evidence in favour of the contribution of environmental factors to the etiology of PD. In this review, we will present current evidence by focusing on specific illustrative examples. SN - 0035-3787 UR - https://www.unboundmedicine.com/medline/citation/20739042/[Parkinson's_disease:_Is_there_a_strong_environmental_contribution]_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0035-3787(10)00334-6 DB - PRIME DP - Unbound Medicine ER -