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[Micronutrients and their relevance for the eye--function of lutein, zeaxanthin and omega-3 fatty acids].
Klin Monbl Augenheilkd. 2011 Jun; 228(6):537-43.KM

Abstract

Micronutrients play an important role in function and health maintenance for the eye. Especially lutein, zeaxanthin and omega-3 fatty acids perform remarkable functions: lutein together with zeaxanthin forms the macular pigment, these carotenoids filter out the damaging blue light component from the sunlight as well as the ultraviolet light which leads to improved contrast sensitivity and less problems with screen glare. Furthermore, the macular pigment has antioxidant and anti-inflammatory effects. The omega-3 fatty acids also possess anti-inflammatory effects and, when converted into neuroprotectin, they protect against oxidative induced apoptosis in the retina. They are also responsible for the fluidity and supply to the photoreceptor membrane. These properties are important for the prevention and treatment of degenerative eye diseases like age-related macular degeneration. However, older people are often not sufficiently supplied of micronutrients in their diet. Because the supply of nutrients can hardly be achieved by dietary change, the additional intake in the form of food supplements is useful in this age group. Scientific studies have shown the positive effects of supplementation with micronutrients such as lutein/zeaxanthin, vitamin C, vitamin E, zinc and omega-3 fatty acids, docosahexaenoic acid and eicosapentaenoic acid (DHA and EPA). Currently available nutritional products are based in part on the ingredients of the ARED study (Age Related Eye Disease Study). According to more recent studies formulations containing lutein and omega-3 fatty acids in physiologically meaningful doses without additional beta-carotene should be preferred. 10 to 20 mg of lutein and zeaxanthin represent a safe daily dose Regarding to the context above, beta-carotene in high doses plays a minor role to the eye and is especially critical for the health of smokers. This paper summarises the functions of the presented micronutrients in the eye and can assist ophthalmologists in advising their patients.

Authors+Show Affiliations

Institut für Ernährungswissenschaft, Universität Potsdam, Arthur-Scheunert-Allee 114-116, Nuthetal. fjschwei@uni-potsdam.deNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

ger

PubMed ID

20740395

Citation

Schweigert, F J., and J Reimann. "[Micronutrients and Their Relevance for the Eye--function of Lutein, Zeaxanthin and Omega-3 Fatty Acids]." Klinische Monatsblatter Fur Augenheilkunde, vol. 228, no. 6, 2011, pp. 537-43.
Schweigert FJ, Reimann J. [Micronutrients and their relevance for the eye--function of lutein, zeaxanthin and omega-3 fatty acids]. Klin Monbl Augenheilkd. 2011;228(6):537-43.
Schweigert, F. J., & Reimann, J. (2011). [Micronutrients and their relevance for the eye--function of lutein, zeaxanthin and omega-3 fatty acids]. Klinische Monatsblatter Fur Augenheilkunde, 228(6), 537-43. https://doi.org/10.1055/s-0029-1245527
Schweigert FJ, Reimann J. [Micronutrients and Their Relevance for the Eye--function of Lutein, Zeaxanthin and Omega-3 Fatty Acids]. Klin Monbl Augenheilkd. 2011;228(6):537-43. PubMed PMID: 20740395.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Micronutrients and their relevance for the eye--function of lutein, zeaxanthin and omega-3 fatty acids]. AU - Schweigert,F J, AU - Reimann,J, Y1 - 2010/08/25/ PY - 2010/8/27/entrez PY - 2010/8/27/pubmed PY - 2012/3/16/medline SP - 537 EP - 43 JF - Klinische Monatsblatter fur Augenheilkunde JO - Klin Monbl Augenheilkd VL - 228 IS - 6 N2 - Micronutrients play an important role in function and health maintenance for the eye. Especially lutein, zeaxanthin and omega-3 fatty acids perform remarkable functions: lutein together with zeaxanthin forms the macular pigment, these carotenoids filter out the damaging blue light component from the sunlight as well as the ultraviolet light which leads to improved contrast sensitivity and less problems with screen glare. Furthermore, the macular pigment has antioxidant and anti-inflammatory effects. The omega-3 fatty acids also possess anti-inflammatory effects and, when converted into neuroprotectin, they protect against oxidative induced apoptosis in the retina. They are also responsible for the fluidity and supply to the photoreceptor membrane. These properties are important for the prevention and treatment of degenerative eye diseases like age-related macular degeneration. However, older people are often not sufficiently supplied of micronutrients in their diet. Because the supply of nutrients can hardly be achieved by dietary change, the additional intake in the form of food supplements is useful in this age group. Scientific studies have shown the positive effects of supplementation with micronutrients such as lutein/zeaxanthin, vitamin C, vitamin E, zinc and omega-3 fatty acids, docosahexaenoic acid and eicosapentaenoic acid (DHA and EPA). Currently available nutritional products are based in part on the ingredients of the ARED study (Age Related Eye Disease Study). According to more recent studies formulations containing lutein and omega-3 fatty acids in physiologically meaningful doses without additional beta-carotene should be preferred. 10 to 20 mg of lutein and zeaxanthin represent a safe daily dose Regarding to the context above, beta-carotene in high doses plays a minor role to the eye and is especially critical for the health of smokers. This paper summarises the functions of the presented micronutrients in the eye and can assist ophthalmologists in advising their patients. SN - 1439-3999 UR - https://www.unboundmedicine.com/medline/citation/20740395/[Micronutrients_and_their_relevance_for_the_eye__function_of_lutein_zeaxanthin_and_omega_3_fatty_acids]_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-0029-1245527 DB - PRIME DP - Unbound Medicine ER -